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大﨑 芳典

Osaki, Yoshinori

医学医療系 , 講師
Faculty of Medicine , Assistant Professor

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  1. 1. Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia Furuta, Yasuhisa; Osaki, Yoshinori; Nakagawa, Yoshimi; Han, Song-Iee (+27 著者) Shimano, Hitoshi
      Journal of atherosclerosis and thrombosis (2024) Semantic Scholar
  2. 2. Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids Han, Song-Iee; Nakakuki, Masanori; Nakagawa, Yoshimi; Wang, Yunong (+20 著者) Shimano, Hitoshi
      PNAS nexus 2: pgad351 (2023) Semantic Scholar
  3. 3. Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function Sekiya, Motohiro; Ma, Yang; Kainoh, Kenta; Saito, Kenji (+19 著者) Shimano, Hitoshi
      CELL REPORTS 42: (2023) Semantic Scholar
  4. 4. Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity Saito, Kenji; Sekiya, Motohiro; Kainoh, Kenta; Yoshino, Ryunosuke (+21 著者) Shimano, Hitoshi
      J Biol Chem 299: 104890 (2023) Semantic Scholar
  5. 5. Takotsubo cardiomyopathy with left ventricle thrombus caused by subacute thyroiditis Yamazaki, Daichi; Osaki, Yoshinori; Suzuki, Hiroaki; Shimano, Hitoshi
      BMJ CASE REPORTS 16: (2023) Semantic Scholar
  6. 6. Identification of key microRNAs regulating ELOVL6 and glioblastoma tumorigenesis Istiqamah, Nurani; Takashi, Matsuzaka; Shimizu, Momo; Motomura, Kaori (+7 著者) Shimano, Hitoshi
      BBA Advances 3: 100078 - 100078 (2023) Semantic Scholar
  7. 7. A case of NASH with genetic predisposition successfully treated with an SGLT2 inhibitor: a possible involvement of mitochondrial dysfunction Nakajima, Rikako; Sekiya, Motohiro; Furuta, Yasuhisa; Miyamoto, Takafumi (+24 著者) Shimano, Hitoshi
      Endocrinology, diabetes & metabolism case reports 2022: (2022) Semantic Scholar
  8. 8. Effects of Branched-Chain Amino Acids on Skeletal Muscle, Glycemic Control, and Neuropsychological Performance in Elderly Persons with Type 2 Diabetes Mellitus: An Exploratory Randomized Controlled Trial Matsuda, Takaaki; Suzuki, Hiroaki; Sugano, Yoko; Suzuki, Yasuhiro (+10 著者) Shimano, Hitoshi
      NUTRIENTS 14: (2022) Semantic Scholar
  9. 9. A case of early-onset diabetes with impaired insulin secretion carrying a PAX6 gene Gln135* mutation Sekiya, Motohiro; Yuhara, Mikiko; Murayama, Yuki; Ohyama Osawa, Mariko (+10 著者) Shimano, Hitoshi
      ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS 2022: (2022) Semantic Scholar
  10. 10. Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice Okajima, Yuka; Matsuzaka, Takashi; Miyazaki, Shun; Motomura, Kaori (+18 著者) Shimano, Hitoshi
      Biochimica et biophysica acta. Molecular basis of disease 1868: 166339 - 166339 (2022) Semantic Scholar
  11. 11. CtBP2 confers protection against oxidative stress through interactions with NRF1 and NRF2 Kainoh, Kenta; Takano, Ryo; Sekiya, Motohiro; Saito, Kenji (+12 著者) Shimano, Hitoshi
      Biochemical and biophysical research communications 562: 146 - 153 (2021) Semantic Scholar
  12. 12. Deciphering genetic signatures by whole exome sequencing in a case of co-prevalence of severe renal hypouricemia and diabetes with impaired insulin secretion Sekiya, Motohiro; Matsuda, Takaaki; Yamamoto, Yuki; Furuta, Yasuhisa (+8 著者) Shimano, Hitoshi
      BMC MEDICAL GENETICS 21: 91 - 91 (2020) Semantic Scholar
  13. 13. Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice Matsuzaka, Takashi; Kuba, Motoko; Koyasu, Saori; Yamamoto, Yuta (+22 著者) Shimano, Hitoshi
      Hepatology (Baltimore, Md.) 71: 1609 - 1625 (2020) Semantic Scholar
  14. 14. CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms Satoh, Aoi; Han, Song-Iee; Araki, Masaya; Nakagawa, Yoshimi (+11 著者) Shimano, Hitoshi
      iScience 23: 100930 - 100930 (2020) Semantic Scholar
  15. 15. Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1 Ma, Yang; Sekiya, Motohiro; Kainoh, Kenta; Matsuda, Takaaki (+9 著者) Shimano, Hitoshi
      Biochemical and biophysical research communications 523: 354 - 360 (2020) Semantic Scholar
  16. 16. The selective PPARα modulator K-877 efficiently activates the PPARα pathway and improves lipid metabolism in mice Takei, Kenta; Han, Song-Iee; Murayama, Yuki; Satoh, Aoi (+11 著者) Shimano, Hitoshi
      Journal of diabetes investigation 8: 446 - 452 (2017) Semantic Scholar
  17. 17. Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression. Kikuchi, Takuya; Orihara, Kana; Oikawa, Fusaka; Han, Song-iee (+15 著者) 島野, 仁
      Mol Metab. 5: 1092 - 1102 (2016) Semantic Scholar
  18. 18. Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system. Yoshimi, Nakagawa; Fusaka, Oikawa; Seiya, Mizuno; Hiroshi, Ohno (+16 著者) Hitoshi, Shimano
      Sci Rep. 6: 27857 - 27857 (2016) Semantic Scholar
  19. 19. Familial Dysalbuminemic Hyperthyroxinemia in a Japanese Man Caused by a Point Albumin Gene Mutation (R218P) Osaki, Yoshinori; Hayashi, Yoshitaka; Nakagawa, Yoshinori; Yoshida, Katsumi (+1 著者) Fukazawa, Hiroshi
      Japanese clinical medicine 7: 9 - 13 (2016) Semantic Scholar
  20. 20. Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy Osaki, Yoshinori; Nakagawa, Yoshimi; Miyahara, Shoko; Iwasaki, Hitoshi (+11 著者) Shimano, Hitoshi
      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 466: 536 - 540 (2015) Semantic Scholar
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  1. 1. カレントテラピー 大﨑,芳典 (担当:分担執筆, 範囲:【脂質異常症治療の最新動向-スタチンを軸とした展開】スタチンの薬理・薬効)
    ライフメディコム 2019年10月
  2. 2. そうだったんだ！脂質異常症 大﨑,芳典 (担当:分担執筆, 範囲:I正常な脂質代謝を理解しよう-3コレステロールの代謝を理解しよう)
    文光堂 2016年9月 (ISBN: 9784830619328)
  3. 3. 日本臨牀 大﨑,芳典 (担当:分担執筆, 範囲:【脂質異常症-基礎・臨床研究の最新知見】リポ蛋白代謝 リポ蛋白代謝にかかわる核内受容体およびリポ蛋白受容体)
    日本臨牀社 2013年6月
  4. 4. 糖尿病の分子標的と治療薬事典 大﨑,芳典 (担当:分担執筆, 範囲:第1部-8章 URAT1)
    羊土社 2013年5月 (ISBN: 9784758120425)
  5. 5. メディカルプラクティス 大﨑,芳典 (担当:分担執筆, 範囲:【実地医家のための 臨床検査のすすめかた・評価のしかた】脂質代謝異常-疑いから確定診断までの検査項目の選択と総合評価)
    文光堂 2012年5月
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