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大﨑 芳典

Osaki, Yoshinori

医学医療系 , 講師
Institute of Medicine , Assistant Professor

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  1. 1. Early insulin averts hyperglycemic crisis in slow-onset durvalumab-induced checkpoint inhibitor-associated autoimmune diabetes mellitus Matsuda, Takaaki; Osaki, Yoshinori; Sekiya, Motohiro; Shimano, Hitoshi
      Journal of rural medicine : JRM 20: 150 (2025)
  2. 2. Longitudinal association of SGLT2 inhibitors and GLP-1RAs on falls in persons with type 2 diabetes Suzuki, Yasuhiro; Suzuki, Hiroaki; Maruo, Kazushi; Matsuda, Takaaki (+6 著者) Shimano, Hitoshi
      Scientific reports 15: 9178 (2025)
  3. 3. Case-based learning: a case of maturity-onset diabetes of the young 5 (MODY5) due to 17q12 microdeletion with a diminished plasma glucagon level Sugano, Yoko; Sekiya, Motohiro; Murayama, Yuki; Osaki, Yoshinori (+5 著者) Shimano, Hitoshi
      DIABETOLOGY INTERNATIONAL Epub: (2025)
  4. 4. Paradoxical cerebral embolism caused by patent foramen ovale in a patient with multiple endocrine neoplasia type 1 and severe primary hyperparathyroidism Matsuda, Takaaki; Osaki, Yoshinori; Sekiya, Motohiro; Shimano, Hitoshi
      BMJ CASE REPORTS 17: (2024)
  5. 5. Variability of urinary albumin to creatinine ratio and eGFR are independently associated with eGFR slope in Japanese with type 2 diabetes: a three-year, single-center, retrospective cohort study Matsuda, Takaaki; Osaki, Yoshinori; Maruo, Kazushi; Matsuda, Erika (+5 著者) Masakazu
      BMC nephrology 25: 264 (2024) Semantic Scholar
  6. 6. Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia Furuta, Yasuhisa; Osaki, Yoshinori; Nakagawa, Yoshimi; Han, Song-Iee (+27 著者) Shimano, Hitoshi
      Journal of atherosclerosis and thrombosis Epub: (2024) Semantic Scholar
  7. 7. Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids Han, Song-Iee; Nakakuki, Masanori; Nakagawa, Yoshimi; Wang, Yunong (+20 著者) Shimano, Hitoshi
      PNAS NEXUS 2: pgad351 (2023) Semantic Scholar
  8. 8. Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function Sekiya, Motohiro; Ma, Yang; Kainoh, Kenta; Yamazaki, Daichi (+18 著者) Shimano, Hitoshi
      CELL REPORTS 42: (2023) Semantic Scholar
  9. 9. Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity Saito, Kenji; Sekiya, Motohiro; Kainoh, Kenta; Yoshino, Ryunosuke (+21 著者) Shimano, Hitoshi
      J Biol Chem 299: 104890 (2023) Semantic Scholar
  10. 10. Takotsubo cardiomyopathy with left ventricle thrombus caused by subacute thyroiditis Yamazaki, Daichi; Osaki, Yoshinori; Suzuki, Hiroaki; Shimano, Hitoshi
      BMJ CASE REPORTS 16: (2023) Semantic Scholar
  11. 11. Identification of key microRNAs regulating ELOVL6 and glioblastoma tumorigenesis Istiqamah, Nurani; Takashi, Matsuzaka; Shimizu, Momo; Motomura, Kaori (+7 著者) Shimano, Hitoshi
      BBA Advances 3: 100078 (2023) Semantic Scholar
  12. 12. A case of NASH with genetic predisposition successfully treated with an SGLT2 inhibitor: a possible involvement of mitochondrial dysfunction Nakajima, Rikako; Sekiya, Motohiro; Furuta, Yasuhisa; Miyamoto, Takafumi (+24 著者) Shimano, Hitoshi
      Endocrinology, diabetes & metabolism case reports 2022: (2022) Semantic Scholar
  13. 13. Effects of Branched-Chain Amino Acids on Skeletal Muscle, Glycemic Control, and Neuropsychological Performance in Elderly Persons with Type 2 Diabetes Mellitus: An Exploratory Randomized Controlled Trial Matsuda, Takaaki; Suzuki, Hiroaki; Sugano, Yoko; Suzuki, Yasuhiro (+10 著者) Shimano, Hitoshi
      NUTRIENTS 14: (2022) Semantic Scholar
  14. 14. A case of early-onset diabetes with impaired insulin secretion carrying a PAX6 gene Gln135* mutation Sekiya, Motohiro; Yuhara, Mikiko; Murayama, Yuki; Ohyama Osawa, Mariko (+10 著者) Shimano, Hitoshi
      ENDOCRINOLOGY DIABETES AND METABOLISM CASE REPORTS 2022: (2022) Semantic Scholar
  15. 15. Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice Okajima, Yuka; Matsuzaka, Takashi; Miyazaki, Shun; Motomura, Kaori (+18 著者) Shimano, Hitoshi
      Biochimica et biophysica acta. Molecular basis of disease 1868: 166339 (2022) Semantic Scholar
  16. 16. CtBP2 confers protection against oxidative stress through interactions with NRF1 and NRF2 Kainoh, Kenta; Takano, Ryo; Sekiya, Motohiro; Saito, Kenji (+12 著者) Shimano, Hitoshi
      Biochemical and biophysical research communications 562: 146 (2021) Semantic Scholar
  17. 17. Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice Matsuzaka, Takashi; Kuba, Motoko; Koyasu, Saori; Yamamoto, Yuta (+22 著者) Shimano, Hitoshi
      Hepatology (Baltimore, Md.) 71: 1609 (2020) Semantic Scholar
  18. 18. Deciphering genetic signatures by whole exome sequencing in a case of co-prevalence of severe renal hypouricemia and diabetes with impaired insulin secretion Sekiya, Motohiro; Matsuda, Takaaki; Yamamoto, Yuki; Furuta, Yasuhisa (+8 著者) Shimano, Hitoshi
      BMC MEDICAL GENETICS 21: 91 (2020) Semantic Scholar
  19. 19. Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1 Ma, Yang; Sekiya, Motohiro; Kainoh, Kenta; Matsuda, Takaaki (+9 著者) Shimano, Hitoshi
      Biochemical and biophysical research communications 523: 354 (2020) Semantic Scholar
  20. 20. CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms Satoh, Aoi; Han, Song-Iee; Araki, Masaya; Nakagawa, Yoshimi (+11 著者) Shimano, Hitoshi
      iScience 23: 100930 (2020) Semantic Scholar
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  1. 1. カレントテラピー 大﨑,芳典 (担当:分担執筆, 範囲:【脂質異常症治療の最新動向-スタチンを軸とした展開】スタチンの薬理・薬効)
    ライフメディコム 2019年10月
  2. 2. そうだったんだ！脂質異常症 大﨑,芳典 (担当:分担執筆, 範囲:I正常な脂質代謝を理解しよう-3コレステロールの代謝を理解しよう)
    文光堂 2016年9月 (ISBN: 9784830619328)
  3. 3. 日本臨牀 大﨑,芳典 (担当:分担執筆, 範囲:【脂質異常症-基礎・臨床研究の最新知見】リポ蛋白代謝 リポ蛋白代謝にかかわる核内受容体およびリポ蛋白受容体)
    日本臨牀社 2013年6月
  4. 4. 糖尿病の分子標的と治療薬事典 大﨑,芳典 (担当:分担執筆, 範囲:第1部-8章 URAT1)
    羊土社 2013年5月 (ISBN: 9784758120425)
  5. 5. メディカルプラクティス 大﨑,芳典 (担当:分担執筆, 範囲:【実地医家のための 臨床検査のすすめかた・評価のしかた】脂質代謝異常-疑いから確定診断までの検査項目の選択と総合評価)
    文光堂 2012年5月
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  3. 3. 亜急性甲状腺炎に甲状腺クリーゼとたこつぼ型心筋症を伴った一例 山崎, 大地; 松本, なこ; 大崎, 芳典; 大内, 奈美; 山本, 由季; 大山, 真理子; 村山, 友樹; 菅野, 洋子; 岩崎, 仁; 関谷, 元博; 矢作, 直也; 鈴木, 浩明; 島野, 仁
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