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金子 新

Kaneko, Shin

iPS細胞研究所 増殖分化機構研究部門 免疫再生治療分野 , 教授
Regenerative Immunotherapy (Shin Kaneko Lab), Dept. Cell Growth and Differentiation, Center for iPS cell Research and Application (CiRA) , Professor

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  1. 1. Current Landscape of Adoptive Cell Therapy and Challenge to Develop "Off-The-Shelf" Therapy for Hepatocellular Carcinoma. Seung Kak Shin; Yuta Mishima; Yoonseok Lee; Oh Sang Kwon (+2 著者) Shin Kaneko
      Journal of gastroenterology and hepatology 40: 791 (2025)
  2. 2. Development of chimeric antigen receptor T cells targeting cancer-expressing podocalyxin. Yuta Mishima; Shintaro Okada; Akihiro Ishikawa; Bo Wang (+3 著者) Shin Kaneko
      Regenerative therapy 28: 292 (2025)
  3. 3. Human iPSC-derived CD4+ Treg-like cells engineered with chimeric antigen receptors control GvHD in a xenograft model. Hisashi Yano; Keiko Koga; Takayuki Sato; Tokuyuki Shinohara (+7 著者) Shin Kaneko
      Cell stem cell 31: 795 (2024) Semantic Scholar
  4. 4. A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism. Shin-Ichiro Takayanagi; Sayaka Chuganji; Masahiro Tanaka; Bo Wang (+14 著者) Shin Kaneko
      Communications biology 7: 685 (2024) Semantic Scholar
  5. 5. Downregulating the immune synapses of iPSC-derived T cells to escape the NK cell-mediated killing(タイトル和訳中) 張 静; 王 博; 蟹江 慶太郎; 吉田 宗弘金子 新
      日本がん免疫学会総会・日本バイオセラピィ学会学術集会総会合同大会プログラム・抄録集 28回・37回: 127 - 127 (2024)
  6. 6. Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy. Sota Kurihara; Akihiro Ishikawa; Shin Kaneko
      Inflammation and regeneration 44: 20 (2024) Semantic Scholar
  7. 7. Differentiation of BCMA-specific induced pluripotent stem cells into rejuvenated CD8αβ+ T cells targeting multiple myeloma. Jooeun Bae; Shuichi Kitayama; Zach Herbert; Laurence Daheron (+10 著者) Kenneth C Anderson
      Blood 143: 895 (2024) Semantic Scholar
  8. 8. Effective and stable gene transduction in rhesus macaque iPSCs capable of T-lineage differentiation utilizing the piggyBac system. Masahiro Tanaka; Yoshihiro Iwamoto; Bo Wang; Eri Imai (+2 著者) Shin Kaneko
      Regenerative therapy 27: 104 (2024) Semantic Scholar
  9. 9. Lineage tracing of T cell differentiation from T-iPSC by 2D feeder-free culture and 3D organoid culture. Yoshitaka Ishiguro; Shoichi Iriguchi; Shinya Asano; Tokuyuki Shinohara (+5 著者) Shin Kaneko
      Frontiers in immunology 14: 1303713 (2023) Semantic Scholar
  10. 10. Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity Alessia Gravina; Grigol Tediashvili; Yueting Zheng; Kumiko A. Iwabuchi (+6 著者) Tobias Deuse
      Cell Stem Cell 30: 1538 (2023) Semantic Scholar
  11. 11. Mini-TCRs: Truncated T cell receptors to generate T cells from induced pluripotent stem cells Shin-ichiro Takayanagi; Bo Wang; Saki Hasegawa; Satoshi Nishikawa (+8 著者) Shin Kaneko
      Molecular Therapy - Methods & Clinical Development 31: 101109 (2023) Semantic Scholar
  12. 12. Humanized mouse models with endogenously developed human natural killer cells for in vivo immunogenicity testing of HLA class I-edited iPSC-derived cells. Charlotte Flahou; Tatsuya Morishima; Natsumi Higashi; Yoshikazu Hayashi (+13 著者) Naoshi Sugimoto
      Biochemical and biophysical research communications 662: 76 (2023) Semantic Scholar
  13. 13. Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells. Tatsuki Ueda; Sara Shiina; Shoichi Iriguchi; Seitaro Terakura (+15 著者) Shin Kaneko
      Nature biomedical engineering 7: 24 (2023) Semantic Scholar
  14. 14. Improved anti-solid tumor response by humanized anti-podoplanin chimeric antigen receptor transduced human cytotoxic T cells in an animal model. Akihiro Ishikawa; Masazumi Waseda; Tomoko Ishii; Mika K Kaneko (+1 著者) Shin Kaneko
      Genes to cells : devoted to molecular & cellular mechanisms 27: 549 (2022) Semantic Scholar
  15. 15. Development of B-cell maturation antigen (BCMA)-specific CD8+ cytotoxic T lymphocytes using induced pluripotent stem cell technology for multiple myeloma. Jooeun Bae; Shuichi Kitayama; Zach Herbert; Laurence Daheron (+3 著者) Kenneth Carl Anderson
      Journal of Clinical Oncology 40: 2542 - 2542 (2022) Semantic Scholar
  16. 16. Sustainable Antiviral Efficacy of Rejuvenated HIV-Specific Cytotoxic T Lymphocytes Generated from Induced Pluripotent Stem Cells. Shoji Miki; Yohei Kawai; Kaori Nakayama-Hosoya; Ryutaro Iwabuchi (+5 著者) Ai Kawana-Tachikawa
      Journal of virology 96: e0221721 (2022) Semantic Scholar
  17. 17. The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells Takeshi Ito; Yohei Kawai; Yutaka Yasui; Shoichi Iriguchi (+7 著者) Shin Kaneko
      Communications Biology 4: (2021) Semantic Scholar
  18. 18. Induced pluripotent stem cell-derived natural killer cells gene-modified to express chimeric antigen receptor-targeting solid tumors Tatsuki Ueda; Shin Kaneko
      International Journal of Hematology 114: 572 (2021) Semantic Scholar
  19. 19. Generation of highly proliferative, rejuvenated cytotoxic T cell clones through pluripotency reprogramming for adoptive immunotherapy. Yohei Kawai; Ai Kawana-Tachikawa; Shuichi Kitayama; Tatsuki Ueda (+2 著者) Shin Kaneko
      Molecular therapy : the journal of the American Society of Gene Therapy 29: 3027 (2021) Semantic Scholar
  20. 20. Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy. Hiroaki Mashima; Rong Zhang; Tsuyoshi Kobayashi; Hirotake Tsukamoto (+10 著者) Yasushi Uemura
      Molecular therapy. Methods & clinical development 21: 171 (2021) Semantic Scholar
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  1. 1. In Vitro Detection of Cellular Adjuvant Properties of Human Invariant Natural Killer T Cells Rong Zhang; Shuichi Kitayama; Tianyi Liu; Norihiro Ueda; Yumi Tokumitsu; Hiroaki Mashima; Hideki Ohdan; Shin Kaneko; Yasushi Uemura (担当:分担執筆)
    Humana Press Inc. 2019年
  2. 2. In Vitro Differentiation of T Cells: From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells Shoichi Iriguchi; Shin Kaneko (担当:分担執筆)
    Humana Press Inc. 2019年
  3. 3. Differentiating CD8αβ T Cells from TCR-Transduced iPSCs for Cancer Immunotherapy Atsutaka Minagawa; Shin Kaneko (担当:分担執筆)
    Humana Press Inc. 2019年
  4. 4. In Vitro Differentiation of T Cells: From Nonhuman Primate-Induced Pluripotent Stem Cells Shoichi Iriguchi; Shin Kaneko (担当:分担執筆)
    Humana Press Inc. 2019年
  5. 5. In Vitro Differentiation of T Cell: From CAR-Modified T-iPSC Tatsuki Ueda; Shin Kaneko (担当:分担執筆)
    Humana Press Inc. 2019年
  6. 6. Redifferentiation of Adaptive Naïve-Like CTL from T-Cell-Derived iPSC Yohei Kawai; Shin Kaneko (担当:分担執筆)
    Humana Press Inc. 2019年

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