ホーム > 柳沢 裕美/ Yanagisawa, Hiromi
柳沢 裕美
Yanagisawa, Hiromi
生存ダイナミクス研究センター , 教授 Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA) , Professor

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血管内皮細胞異常とマクロファージ集積が大動脈解離発症を引き起こす
2025-05-20
木村 健一 柳沢 裕美

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血管狭窄時の新生内膜形成に内皮間葉転換が寄与する〜血管リモデリングの仕組みを解明〜
2022-12-22
柳沢 裕美

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ラマン分光法における大動脈瘤の診断マーカースペクトルを同定
2021-06-08
柳沢 裕美

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血管障害後の新生内膜形成に関わる細胞の役割を解明
2021-06-08
木村 健一 柳沢 裕美

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How blood vessels feel the pressure
2021-05-31
柳沢 裕美 山城 義人

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細胞外環境から生命現象を捉える | 柳沢 裕美 | 筑波大学研究者カタログ
2021-01-06
柳沢 裕美 山城 義人 木村 健一

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大動脈瘤発症の分子機構解明と新しい治療標的分子の探索
2020-09-25
柳沢 裕美 山城 義人 平松 祐司

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慢性腎臓病に対する新規治療法の開発にむけた基礎研究
2020-09-25
柳沢 裕美
オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
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1.
Editorial: New trends in vascular biology 2024.
Chelvanambi, Sarvesh; Chen, Hong; Vries, Margreet R De; Fang, Yun (+5 著者) Aikawa, Masanori
Front Cardiovasc Med. 1649558 (2025)
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2.
Novel Aortic Dissection Model Links Endothelial Dysfunction and Immune Infiltration
Kimura, K.; Motoyama, E.; Kanki, S.; Asano, K. (+15 著者) Yanagisawa, H.
Circulation Research 137: (2025)
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3.
Spatiotemporal dynamics of CD73 in mouse retina under physiological conditions
ISHII, Ryutaro; Sakurai, Keisuke; Hosomi, Nao; Fleischmann, Bernd K. (+2 著者) Yanagisawa, Hiromi
bioRxiv (2025)
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4.
Editorial: New trends in vascular biology 2024
Chelvanambi, Sarvesh; Chen, Hong; De Vries; Margreet R. (+6 著者) Aikawa, Masanori
Frontiers in cardiovascular medicine 12: (2025)
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5.
Endothelial cell (EC)-specific Ctgf/Ccn2 expression increases EC reprogramming and atherosclerosis
Li, F.; Kumar, S.; Pokutta-Paskaleva, A.; Kang, D.-W. (+17 著者) Brewster, L.P.
Matrix Biology 136: 102 (2025)
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6.
The matricellular protein Fibulin-5 regulates R-cell proliferation in an autocrine/paracrine manner
Okuyama, Tomoko; Tsuno, Takahiro; Inoue, Ryota; Fukushima, Setsuko (+12 著者) Shirakawa, Jun
ISCIENCE 28: 111856 (2025)
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7.
Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice
Hossain, A.S.; Clarin; M.T.R.D.C.; Kimura, K. (+14 著者) Yanagisawa, H.
Matrix Biology 135: 24 (2025)
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8.
Novel Insights into the Aortic Mechanical Properties of Mice Modeling Hereditary Aortic Diseases
Dubacher, N.; Sugiyama, K.; Smith, J.D.; Nussbaumer, V. (+8 著者) Matyas, G.
Thrombosis and Haemostasis 125: (2024)
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9.
A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta
Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi (+17 著者) Yanagisawa, Hiromi
Biorxiv (2024) Semantic Scholar
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10.
Cardiac and perivascular myofibroblasts, matrifibrocytes, and immune fibrocytes in hypertension; commonalities and differences with myocardial infarction and other cardiovascular diseases
Torimoto, K.; Elliott, K.; Nakayama, Y.; Yanagisawa, H.Eguchi, S.
Cardiovascular Research 120: (2024) Semantic Scholar
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11.
Unraveling the Role of TGFβ Signaling in Thoracic Aortic Aneurysm and Dissection Using Fbn1 Mutant Mouse Models
Violette, Deleeuw; Carlson, Eric; Renard, Marjolijn; Zientek, Keith D (+13 著者) Sakai, Lynn Y
Matrix Biology 123: 17 (2023) Semantic Scholar
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12.
Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin
Raja, E.; Clarin; M.T.R.D.C.; Yanagisawa, H.
International Journal of Molecular Sciences 24: 14274 (2023) Semantic Scholar
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13.
Abstract P3026: Multimodal Imaging To Identify Pre-signals For Acute Aortic Dissection By Using Marfan Syndrome Model Mouse
KAORI SUGIYAMA; Masahiro Ando; Hiroko Matsunaga; Ryota Wagatsuma (+5 著者) Haruko Takeyama
Circulation Research 133: (2023) Semantic Scholar
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14.
Aortic rupture force in mice modelling hereditary aortic diseases
Dubacher, Nicolo; Sugiyama, Kaori; Smith, Jeffrey; Nussbaumer, Vanessa (+5 著者) Matyas, Gabor
EUROPEAN JOURNAL OF HUMAN GENETICS 31: 415 (2023)
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15.
Protective Role of Endothelial Fibulin-4 in Valvulo-Arterial Integrity
Nguyen; Tram Anh Vu; Lino, Caroline Antunes; Hang, Huynh Thuy (+7 著者) Yanagisawa, Hiromi
Journal of the American Heart Association 12: (2023) Semantic Scholar
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16.
Fibulin7 aggravates calcium oxalate-induced acute kidney injury by binding to calcium oxalate crystals
Sugiura, H.; Tsunezumi, J.; Yanagisawa, H.; Futaya, M. (+1 著者) Tsuchiya, K.
Journal of Cellular Physiology 238: 165 (2023) Semantic Scholar
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17.
Partial endothelial-to-mesenchymal transition mediated by HIF-induced CD45 in neointima formation upon carotid artery ligation
Yamashiro, Yoshito; Ramirez, Karina; Nagayama, Kazuaki; Hattori, Naoko (+4 著者) Yanagisawa, Hiromi
Cardiovascular research (2022) Semantic Scholar
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18.
TBX1 targets the miR-200-ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties.
Noriko Funato; Hiromi Yanagisawa
Scientific reports 12: 20188 (2022) Semantic Scholar
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19.
The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging
Erna Raja; Gopakumar Changarathil; Lalhaba Oinam; Jun Tsunezumi (+5 著者) Aiko Sada
EMBO reports (2022) Semantic Scholar
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20.
マルファン症候群モデルマウスを用いた急性大動脈解離シグナル探索とラベルフリーイメージング作製
杉山 夏緒里; 安藤 正浩; 我妻 竜太; 松永 浩子 (+1 著者) 竹山 春子
日本結合組織学会学術大会プログラム・抄録集 54回: 102 (2022)
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1.
Biomechanics of the Aorta: Modelling for Patient Care
Kailash, Keshav; Clarin; Maria Thea; Rane; Dela Cruz; Sheikh, Md Al Amin; Yanagisawa, Hiromi; Wagenseil; Jessica E.
Elsevier 2024年6月
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2.
血管・リンパ管の機能制御と疾患メカニズム
山城義人; 柳沢裕美
化学同人 2022年8月 (ISBN: 9784759817355)
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3.
心臓
木村, 健一; 柳沢裕美
(担当:分担執筆, 範囲:大動脈瘤への分子生物学的アプローチ)
日本医学出版 2022年6月
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4.
医学のあゆみ
大動脈瘤形成に関与するメカノトランスダクション機構
(担当:共著, 範囲:山城義人; 柳沢裕美)
2019年5月18日
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5.
Advances in Stem Cells and their Niches
Oinam, L; Changarathil, G; Ngo, YX; Yanagisawa, H; Sada, A
(担当:分担執筆, 範囲:Epidermal stem cell lineages)
2019年4月
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121.
Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection.
Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi; Sheikh, Md Al Amin; Deleeuw, Violette; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Yanagisawa, Hiromi
International Vascular Biology Meeting 2024
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122.
血管と血管外細胞の相互作用から読み解く大動脈解離の発症機序
柳沢, 裕美
第46回日本分子生物学会年会 日本分子生物学会 招待有り
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123.
解離大動脈壁に出現する細胞集団の時空間解析と病態解明
柳沢, 裕美
心血管代謝週間 日本血管生物医学会 招待有り
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124.
Abnormal mechanotransduction and its implication in aortic disease
柳沢, 裕美
IDWGIG symposium RIKEN 招待有り
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125.
Spatio-temporal analysis of cell populations in dissecting aortic wall
柳沢, 裕美
日本循環器病学会 Japanese Circulation Society 招待有り
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126.
Cell-matrix interactions in the maintenance of vascular wall
柳沢, 裕美
Korean Society for Biochemistry and Molecular Biology Korean Society for Biochemistry and Molecular Biology 招待有り
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127.
Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis
Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Deleeuw, Violette; Kanki, Sachiko; Asano, Keiichi; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Ozaki, Haruka; Yanagisawa, Hiromi
the annual Tsukuba Global Science Week (TGSW) 2023
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128.
A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes Tight Skin Phenotype
ASM; Sakhawat Hossain; Maria, Thea Rane; Dela Cruz; Koichiro, Uto; Eri, Motoyama; Sumio, Ohtsuki; Keiichi, Asano; Kenichi, Kimura; Yuki, Taga; Kazunori, Mizuno; Tomoyuki, Nakamura; Sachiko, Kanki; Erna, Raja; Hiromi, Yanagisawa
第7回エラスチン・関連分子研究会学術集会
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129.
Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis
Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Deleeuw, Violette; Kanki, Sachiko; Asano, Keiichi; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Ozaki, Haruka; Yanagisawa, Hiromi
第7回日本循環器学会 基礎研究フォーラム(BCVR)
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130.
骨髄微小環境におけるCD73陽性細胞の細胞系譜解析
木村, 健一; Bernd, Fleischmann; 柳沢, 裕美
第46回日本分子生物学会年会
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131.
Maintaining differentiated cell identity during aging -- insights from Drosophila enteroendocrine cells
Qian, Qingyin; Hayashi, Makoto; Kimura, Ken-ichi; Yanagisawa, Hiromi; Niwa, Ryusuke
第46回日本分子生物学会年会
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132.
Multimodal imaging to identify pre-signals for acute aortic dissection by using Marfan syndrome model mouse
Sugiyama, Kaori; Ando, Masahiro; Wagatsuma, Ryota; Matsunaga, Hiroko; Uchino, Haruki; Kimura, Kenichi; Ramirez, Francesco; Schenke-Layland, Katja; Arita, Makoto; Yanagisawa, Hiromi; Takeyama, Haruko
Basic Cardiovascular Sciences Scientific Sessions 2024
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133.
Investigation of the molecular mechanism of BAV-associated aortopathy
Liu, Chang; Tokunaga, Chiho; Sugiyama, Kaori; Kimura, Kenichi; Tsukda, Toru; Kato, Hideyuki; Matsubara, Muneaki; Osaka, Motoo; Sakamoto, Hiroaki; Matsunaga, Hiroko; Takeyama, Haruko; Yanagisawa, Hiromi; Hiramatsu, Yuji
The 76th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery
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134.
A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes an Abnormal Skin Phenotype
ASM; Sakhawat Hossain; Yuki, Taga; Maria, Thea Rane; Dela Cruz; Kazunori, Mizuno; Koichiro, Uto; Eri, Motoyama; Sumio, Ohtsuki; Keiichi, Asano; Kenichi, Kimura; Tomoyuki, Nakamura; Sachiko, Kanki; Erna, Raja; Hiromi, Yanagisawa
Tissue, Matrix, and Pathobiology: Joint Meeting of ASMB, HCS, and ASIP
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135.
A Novel Mouse Model of Aortic Dissection Caused by a Point Mutation in the Hybrid Domain of the Fibrillin-1 Gene
Yanagisawa, Hiromi
Gordon Research Conference on Elastin, Elastic Fibers and Microfibrils Gordon Research Conference 招待有り
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136.
The expanding roles of short fibulins: elastogenesis and beyond
Yanagisawa, Hiromi
Gordon Research Seminar on Elastin, Elastic Fibers and Microfibrils Gordon Research Conference 招待有り
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137.
新規Fibrillin-1点変異マウスモデルを用いた大動脈解離発症機序の解明
本山絵理; 木村, 健一; 神吉, 佐智子; 中邨, 智之; 柳沢, 裕美
第55回日本結合組織学会
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138.
細胞外マトリクスと血管壁の維持機構
柳沢, 裕美
CVEM オンラインセミナー CVEM 招待有り
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139.
Matrix-cell Interactions and Aortic Aneurysms
Yanagisawa, Hiromi
European Circulation Society European Circulation Society 招待有り
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140.
Matrix-cell interactions and aortic diseases
Yanagisawa, Hiromi
International Vascular Biology Meeting IVBM 招待有り
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