ホーム > 柳沢 裕美/ Yanagisawa, Hiromi
柳沢 裕美
Yanagisawa, Hiromi
生存ダイナミクス研究センター , 教授 Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA) , Professor

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血管のしなやかさを生む「弾性線維」の立体構築に成功 ―三次元血管モデルを確立―
2025-11-17
柳沢 裕美

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血管内皮細胞異常とマクロファージ集積が大動脈解離発症を引き起こす
2025-05-20
木村 健一 柳沢 裕美

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血管狭窄時の新生内膜形成に内皮間葉転換が寄与する〜血管リモデリングの仕組みを解明〜
2022-12-22
柳沢 裕美

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ラマン分光法における大動脈瘤の診断マーカースペクトルを同定
2021-06-08
柳沢 裕美

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血管障害後の新生内膜形成に関わる細胞の役割を解明
2021-06-08
木村 健一 柳沢 裕美

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How blood vessels feel the pressure
2021-05-31
柳沢 裕美 山城 義人

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細胞外環境から生命現象を捉える | 柳沢 裕美 | 筑波大学研究者カタログ
2021-01-06
柳沢 裕美 山城 義人 木村 健一

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大動脈瘤発症の分子機構解明と新しい治療標的分子の探索
2020-09-25
柳沢 裕美 山城 義人 平松 祐司

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慢性腎臓病に対する新規治療法の開発にむけた基礎研究
2020-09-25
柳沢 裕美
オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
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1.
Mouse models of aortic aneurysm and dissection: pathophysiological insights and translational perspectives
He, Chenyang; Yanagisawa, Hiromi; Hsiai, Tzung K.; Xu, Suowen
Journal of advanced research (2026) Semantic Scholar
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2.
Circadian regulation of bladder capacity and extracellular matrix variation independent of central clock–driven behavioral rhythms
Suzuki, Shuhei; Negoro, Hiromitsu; Nonaka, Haruna; Chihara, Ichiro (+5 著者) Nishiyama, Hiroyuki
Communications biology (2026)
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3.
Structural and transcriptomic alterations underlying the progression of aortic dissection in Fbn1G234D/G234D mice
Sheikh, Md Al Amin; KIMURA, Kenichi; Motoyama, Eri; Asano, Keiichi (+12 著者) Yanagisawa, Hiromi
Scientific Reports (2026)
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4.
The epidermal stem cell-supporting matricellular protein fibulin 7 modulates skin inflammatory response in a psoriasis model
Erna, Raja; Tomoko, Machida; Narenmandula; Karolina, Edlund (+9 著者) Hiromi, Yanagisawa
Biorxiv (2026)
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5.
Spatial organization of epithelial heterogeneity through undulating structures of the skin and oral mucosa
Mizuho Ishikawa; Yen Xuan Ngo; Ikuto Nishikawa; Hiroko Kato (+5 著者) Aiko Sada
Journal of Investigative Dermatology (2026) Semantic Scholar
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6.
Development of a three-dimensional experimental vascular model with smooth muscle cell-derived cross-linked elastic fiber assembly
Sawada, Yuri; Tanifuji, Shota; Nakamura, Takashi; Uchida, Keiko (+10 著者) Yokoyama, Utako
ACTA BIOMATERIALIA 208: 266 (2025) Semantic Scholar
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7.
Editorial: New trends in vascular biology 2024.
Chelvanambi, Sarvesh; Chen, Hong; Vries, Margreet R De; Fang, Yun (+5 著者) Aikawa, Masanori
Front Cardiovasc Med. 1649558 (2025)
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8.
Integrin-Binding Matricellular Protein Fibulin-5 Maintains Epidermal Stem Cell Heterogeneity During Skin Aging
Wenxin Fan; Mizuho Ishikawa; Erna Raja; Ahmed M. Hegazy (+5 著者) Aiko Sada
(2025)
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9.
Novel Aortic Dissection Model Links Endothelial Dysfunction and Immune Infiltration
Kimura, K.; Motoyama, E.; Kanki, S.; Asano, K. (+15 著者) Yanagisawa, H.
Circulation Research 137: (2025) Semantic Scholar
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10.
Spatiotemporal dynamics of CD73 in mouse retina under physiological conditions
ISHII, Ryutaro; Sakurai, Keisuke; Hosomi, Nao; Fleischmann, Bernd K. (+2 著者) Yanagisawa, Hiromi
bioRxiv (2025) Semantic Scholar
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11.
Editorial: New trends in vascular biology 2024
Chelvanambi, Sarvesh; Chen, Hong; De Vries; Margreet R. (+6 著者) Aikawa, Masanori
Frontiers in cardiovascular medicine 12: (2025) Semantic Scholar
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12.
Endothelial cell (EC)-specific Ctgf/Ccn2 expression increases EC reprogramming and atherosclerosis
Li, F.; Kumar, S.; Pokutta-Paskaleva, A.; Kang, D.-W. (+17 著者) Brewster, L.P.
Matrix Biology 136: 102 (2025) Semantic Scholar
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13.
The matricellular protein Fibulin-5 regulates R-cell proliferation in an autocrine/paracrine manner
Okuyama, Tomoko; Tsuno, Takahiro; Inoue, Ryota; Fukushima, Setsuko (+12 著者) Shirakawa, Jun
ISCIENCE 28: 111856 (2025) Semantic Scholar
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14.
Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice
Hossain, A.S.; Clarin; M.T.R.D.C.; Kimura, K. (+14 著者) Yanagisawa, H.
Matrix Biology 135: 24 (2025)
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15.
Defining epithelial stem cell heterogeneity through undulating structures of the skin and oral mucosa
Mizuho Ishikawa; Yen Xuan Ngo; Ikuto Nishikawa; Hiroko Kato (+5 著者) Aiko Sada
(2025) Semantic Scholar
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16.
Novel Insights into the Aortic Mechanical Properties of Mice Modeling Hereditary Aortic Diseases
Dubacher, N.; Sugiyama, K.; Smith, J.D.; Nussbaumer, V. (+8 著者) Matyas, G.
Thrombosis and Haemostasis 125: (2024)
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17.
A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta
Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi (+17 著者) Yanagisawa, Hiromi
Biorxiv (2024) Semantic Scholar
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18.
Cardiac and perivascular myofibroblasts, matrifibrocytes, and immune fibrocytes in hypertension; commonalities and differences with myocardial infarction and other cardiovascular diseases
Torimoto, K.; Elliott, K.; Nakayama, Y.; Yanagisawa, H.Eguchi, S.
Cardiovascular Research 120: (2024) Semantic Scholar
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19.
Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin
Raja, E.; Clarin; M.T.R.D.C.; Yanagisawa, H.
International Journal of Molecular Sciences 24: 14274 (2023) Semantic Scholar
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20.
Unraveling the Role of TGFβ Signaling in Thoracic Aortic Aneurysm and Dissection Using Fbn1 Mutant Mouse Models
Violette, Deleeuw; Carlson, Eric; Renard, Marjolijn; Zientek, Keith D (+13 著者) Sakai, Lynn Y
Matrix Biology 123: 17 (2023) Semantic Scholar
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1.
Biomechanics of the Aorta: Modelling for Patient Care
Kailash, Keshav; Clarin; Maria Thea; Rane; Dela Cruz; Sheikh, Md Al Amin; Yanagisawa, Hiromi; Wagenseil; Jessica E.
Elsevier 2024年6月
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2.
血管・リンパ管の機能制御と疾患メカニズム
山城義人; 柳沢裕美
化学同人 2022年8月 (ISBN: 9784759817355)
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3.
心臓
木村, 健一; 柳沢裕美
(担当:分担執筆, 範囲:大動脈瘤への分子生物学的アプローチ)
日本医学出版 2022年6月
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4.
医学のあゆみ
大動脈瘤形成に関与するメカノトランスダクション機構
(担当:共著, 範囲:山城義人; 柳沢裕美)
2019年5月18日
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5.
Advances in Stem Cells and their Niches
Oinam, L; Changarathil, G; Ngo, YX; Yanagisawa, H; Sada, A
(担当:分担執筆, 範囲:Epidermal stem cell lineages)
2019年4月
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141.
Development of nanoparticles to induce M1-to-M2 switch as a treatment for aortic dissection in Fbn1 mutant mice.
Clarin; M.T.R.D.C; E., Motoyama; A., Nabil; S., Kanki; Kimura, Kenichi; Ebara, Mitsuhiro; H., Yanagisawa
World Biomaterials Congress
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142.
Development of nanoparticles to induce M1-to-M2 switch as a treatment for aortic dissection in Fbn1 mutant mice.
Clarin; M.T.R.D.C; E., Motoyama; A., Nabil; S., Kanki; Uto, Koichiro; Kimura, Kenichi; Ebara, Mitsuhiro; H., Yanagisawa
International Vascular Biology Meeting 2024
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143.
Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection.
Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi; Sheikh, Md Al Amin; Deleeuw, Violette; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Yanagisawa, Hiromi
International Vascular Biology Meeting 2024
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144.
血管と血管外細胞の相互作用から読み解く大動脈解離の発症機序
柳沢, 裕美
第46回日本分子生物学会年会 日本分子生物学会 招待有り
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145.
解離大動脈壁に出現する細胞集団の時空間解析と病態解明
柳沢, 裕美
心血管代謝週間 日本血管生物医学会 招待有り
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146.
Abnormal mechanotransduction and its implication in aortic disease
柳沢, 裕美
IDWGIG symposium RIKEN 招待有り
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147.
Spatio-temporal analysis of cell populations in dissecting aortic wall
柳沢, 裕美
日本循環器病学会 Japanese Circulation Society 招待有り
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148.
Cell-matrix interactions in the maintenance of vascular wall
柳沢, 裕美
Korean Society for Biochemistry and Molecular Biology Korean Society for Biochemistry and Molecular Biology 招待有り
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149.
Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis
Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Deleeuw, Violette; Kanki, Sachiko; Asano, Keiichi; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Ozaki, Haruka; Yanagisawa, Hiromi
the annual Tsukuba Global Science Week (TGSW) 2023
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150.
A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes Tight Skin Phenotype
ASM; Sakhawat Hossain; Maria, Thea Rane; Dela Cruz; Koichiro, Uto; Eri, Motoyama; Sumio, Ohtsuki; Keiichi, Asano; Kenichi, Kimura; Yuki, Taga; Kazunori, Mizuno; Tomoyuki, Nakamura; Sachiko, Kanki; Erna, Raja; Hiromi, Yanagisawa
第7回エラスチン・関連分子研究会学術集会
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151.
Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis
Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Deleeuw, Violette; Kanki, Sachiko; Asano, Keiichi; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Ozaki, Haruka; Yanagisawa, Hiromi
第7回日本循環器学会 基礎研究フォーラム(BCVR)
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152.
骨髄微小環境におけるCD73陽性細胞の細胞系譜解析
木村, 健一; Bernd, Fleischmann; 柳沢, 裕美
第46回日本分子生物学会年会
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153.
Maintaining differentiated cell identity during aging -- insights from Drosophila enteroendocrine cells
Qian, Qingyin; Hayashi, Makoto; Kimura, Ken-ichi; Yanagisawa, Hiromi; Niwa, Ryusuke
第46回日本分子生物学会年会
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154.
Multimodal imaging to identify pre-signals for acute aortic dissection by using Marfan syndrome model mouse
Sugiyama, Kaori; Ando, Masahiro; Wagatsuma, Ryota; Matsunaga, Hiroko; Uchino, Haruki; Kimura, Kenichi; Ramirez, Francesco; Schenke-Layland, Katja; Arita, Makoto; Yanagisawa, Hiromi; Takeyama, Haruko
Basic Cardiovascular Sciences Scientific Sessions 2024
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155.
Investigation of the molecular mechanism of BAV-associated aortopathy
Liu, Chang; Tokunaga, Chiho; Sugiyama, Kaori; Kimura, Kenichi; Tsukda, Toru; Kato, Hideyuki; Matsubara, Muneaki; Osaka, Motoo; Sakamoto, Hiroaki; Matsunaga, Hiroko; Takeyama, Haruko; Yanagisawa, Hiromi; Hiramatsu, Yuji
The 76th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery
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156.
A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes an Abnormal Skin Phenotype
ASM; Sakhawat Hossain; Yuki, Taga; Maria, Thea Rane; Dela Cruz; Kazunori, Mizuno; Koichiro, Uto; Eri, Motoyama; Sumio, Ohtsuki; Keiichi, Asano; Kenichi, Kimura; Tomoyuki, Nakamura; Sachiko, Kanki; Erna, Raja; Hiromi, Yanagisawa
Tissue, Matrix, and Pathobiology: Joint Meeting of ASMB, HCS, and ASIP
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157.
A Novel Mouse Model of Aortic Dissection Caused by a Point Mutation in the Hybrid Domain of the Fibrillin-1 Gene
Yanagisawa, Hiromi
Gordon Research Conference on Elastin, Elastic Fibers and Microfibrils Gordon Research Conference 招待有り
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158.
The expanding roles of short fibulins: elastogenesis and beyond
Yanagisawa, Hiromi
Gordon Research Seminar on Elastin, Elastic Fibers and Microfibrils Gordon Research Conference 招待有り
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159.
新規Fibrillin-1点変異マウスモデルを用いた大動脈解離発症機序の解明
本山絵理; 木村, 健一; 神吉, 佐智子; 中邨, 智之; 柳沢, 裕美
第55回日本結合組織学会
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160.
細胞外マトリクスと血管壁の維持機構
柳沢, 裕美
CVEM オンラインセミナー CVEM 招待有り
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