ホーム > 小林 麻己人/ Kobayashi, Makoto
小林 麻己人
Kobayashi, Makoto
医学医療系 , 教授 Institute of Medicine , Professor

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生活習慣病の原因となる小胞体ストレスを緩和するしくみ ~Nrf2システムの活性化~
2018-11-27
小林 麻己人

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#084:ゼブラフィッシュにこだわるわけ
2018-01-16
小林 麻己人

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血球をつくるしくみを解明 ~ヘマンジオブラストではたらくエピジェネティクス制御~
2016-09-27
小林 麻己人
オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
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1.
Enhancement of 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity by lipopolysaccharide in developing zebrafish lacking canonical pattern recognition pathways
Kitamura, Hayato; Tanaka, Katsuki; Wang, Huan; Nakamura, Tatsuro (+1 著者) Teraoka, Hiroki
Comp. Biochem. Physiol. C Toxicol. Pharmacol. 297: 110261 (2025)
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2.
Development of oral pH-sensitive redox nanotherapeutics for gastric ulcer therapy
Tang, Minh-Dat Quoc; Tran, Nhi Bao; Nguyen, Thu-Ha Thi; Nguyen, Khanh-Uyen Hoang (+5 著者) Vong, Long Binh
J. Control. Release 375: 758 (2024) Semantic Scholar
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3.
Novel Indirect Antioxidant Activity Independent of Nrf2 Exerted by Lactic Acid Bacteria
Sato, Ayaka; Watanabe, Asami; Muraki, Kyoji; Kimoto-Nira, HiromiKobayashi, Makoto
Int. J. Mol. Sci. 25: (2024) Semantic Scholar
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4.
Polarization-artifact reduction and accuracy improvement of Jones-matrix polarization-sensitive optical coherence tomography by multi-focus-averaging based multiple scattering reduction
Zhu, Lida; Makita, Shuichi; Tamaoki, Junya; Zhu, Yiqiang (+3 著者) Yasuno, Yoshiaki
Biomed. Opt. Express 15: 256 (2024) Semantic Scholar
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5.
Physical characteristics and flavor releases of spice pastes processed by micro wet milling
Ogawa, Natsumi; Bui, Thi Bao Chau; Kobayashi, Makoto; Kusano, Miyako (+1 著者) Kitamura, Yutaka
JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI 70: 575 - 582 (2023) Semantic Scholar
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6.
Congenital anaemia associated with loss-of-function variants in DNA polymerase epsilon 1
Takeuchi, Ichiro; Tanase-Nakao, Kanako; Ogawa, Ayame; Sugawara, Tohru (+20 著者) Ishiguro, Akira
J. Med. Genet. 61: 239 (2023) Semantic Scholar
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7.
研究者のビジュアルコミュニケーションデザイン力を育成するルーブリック案の検討
田中, 佐代子; 小林麻己人; 三輪, 佳宏
日本科学教育学会第47回年会論文集 47: 631 (2023)
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8.
LSD1 promotes the egress of hematopoietic stem and progenitor cells into the bloodstream during the endothelial-to-hematopoietic transition
Tamaoki, Junya; Maeda, Hiroki; Kobayashi, Isao; Takeuchi, Miki (+6 著者) Kobayashi, Makoto
Dev. Biol. 501: 92 (2023) Semantic Scholar
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9.
Multi-focus averaging for multiple scattering suppression in optical coherence tomography
Zhu, Lida; Makita, Shuichi; Tamaoki, Junya; Lichtenegger, Antonia (+3 著者) Yasuno, Yoshiaki
Biomed. Opt. Express 14: 4828 (2023) Semantic Scholar
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10.
Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging
Tomita, Kiriko; Makita, Shuichi; Fukutake, Naoki; Morishita, Rion (+8 著者) Yasuno, Yoshiaki
Biomed. Opt. Express 14: 3100 (2023) Semantic Scholar
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11.
Genetic hyperactivation of Nrf2 causes larval lethality in Keap1a and Keap1b-double-knockout zebrafish.
Lixuan Bian; Vu Thanh Nguyen; Junya Tamaoki; Yuka Endo (+2 著者) Makoto Kobayashi
Redox Biol. 62: 102673 (2023) Semantic Scholar
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12.
Design of a new self-assembling antioxidant nanomedicine to ameliorate oxidative stress in zebrafish embryos.
Babita Shashni; Junya Tamaoki; Makoto Kobayashi; Yukio Nagasaki
Acta Biomater. 159: 367 (2023) Semantic Scholar
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13.
Augmentation of Pectoral Fin Teratogenicity by Thalidomide in Human Cytochrome P450 3A-Expressing Zebrafish.
Wenjing Dong; Ippo Akasaka; Akifumi Komiyama; Tatsuro Nakamura (+4 著者) Hiroki Teraoka
Pharmaceuticals 16: (2023) Semantic Scholar
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14.
Transgenic Zebrafish Expressing Rat Cytochrome P450 2E1 (CYP2E1): Augmentation of Acetaminophen-Induced Toxicity in the Liver and Retina.
Yoshinori Sato; Wenjing Dong; Tatsuro Nakamura; Naohiro Mizoguchi (+5 著者) Hiroki Teraoka
Int. J. Mol. Sci. 24: (2023) Semantic Scholar
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15.
Longitudinal investigation of a xenograft tumor zebrafish model using polarization-sensitive optical coherence tomography
Lichtenegger, Antonia; Tamaoki, Junya; Licandro, Roxane; Mori, Tomoko (+8 著者) Yasuno, Yoshiaki
Sci. Rep. 12: (2022) Semantic Scholar
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16.
Soy-derived equol induces antioxidant activity in zebrafish in an Nrf2-independent manner
Watanabe, A; Muraki, K; Tamaoki, J; Kobayashi, Makoto
Int. J. Mol. Sci. 23: 5243 (2022) Semantic Scholar
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17.
Multicontrast investigation of in vivo wildtype zebrafish in three development stages using polarization-sensitive optical coherence tomography
Lichtenegger, Antonia; Mukherjee, Pradipta; Tamaoki, Junya; Bian, Lixuan (+7 著者) Yasuno, Yoshiaki
J. Biomed. Opt. 27: 016001 (2022) Semantic Scholar
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18.
Pathogenic variants in the survival of motor neurons complex gene GEMIN5 cause cerebellar atrophy
Saida, Ken; Tamaoki, Junya; Sasaki, Masayuki; Haniffa, Muzhirah (+15 著者) Matsumoto, Naomichi
Clin. Genet. 100: 722 (2021)
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19.
Oxidative stress inducers potentiate 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated pre-cardiac edema in larval zebrafish
Tanaka, Katsuki; Adachi, Hikaru; Akasaka, Hironobu; Tamaoki, Junya (+3 著者) Teraoka, Hiroki
J. Vet. Med. Sci. 83: 1050 (2021)
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20.
Generation and characterization of keap1a- and keap1b-knockout zebrafish.
Vu Thanh Nguyen; Lixuan Bian; Junya Tamaoki; Shiro Otsubo (+2 著者) Makoto Kobayashi
Redox Biol. 36: 101667 (2020) Semantic Scholar
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1.
動物実験代替法とNew Approach Methodologiesの開発・利用動向
佐藤, 綾香; 小林, 麻己人
2023年9月 (ISBN: 9784781317472)
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2.
スパイス・ハーブの機能と応用
小林麻己人
(担当:分担執筆, 範囲:酸化ストレス障害モデル動物を駆使した香辛料成分の研究)
恒星社厚生閣シーエムシー出版 2020年10月
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3.
魚類発生学の基礎
磯貝純夫; 小林麻己人; 森友忠昭; 齋藤絵里奈; 藤田深里; 出口友則
(担当:分担執筆, 範囲:循環系の発生)
恒星社厚生閣 2018年9月 (ISBN: 9784769914853)
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4.
南山堂 医学大辞典 20版
小林麻己人
(担当:分担執筆, 範囲:エピジェネティクス、遺伝学)
南山堂 2015年4月
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5.
ADVANCES IN ENZYME REGULATION, VOL 46, PROCEEDINGS
Kobayashi, Makoto; Yamamoto, Masayuki
(担当:分担執筆, 範囲:Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species)
ELSEVIER SCIENCE BV 2006年1月
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6.
転写因子・転写制御キーワードブック(田村隆明・山本雅之編)
小林麻己人
羊土社 2006年1月
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7.
シリーズバイオサイエンスの新世紀/第1巻 「遺伝子の構造と機能」(山本雅之編)
小林麻己人; 山本雅之
共立出版 2001年1月
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8.
The subunit-subunit contact sites of the influenza virus RNA polymerase
Toyoda;T; Adyshev;D.M; Kobayashi;M; Iwata;A; Ueda;S; Ishihama;A; 小林, 麻己人
(担当:監修)
Options for the control of influenza III Options for the control of influenza III Elsevier Science B. V. 1996年1月
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9.
Formation and control of influenza virus RNA polymerase
Ishihama;A; Toyoda;T; Kobayashi;M; Yasuda;J; Asano;Y; Nakayama;M; 小林, 麻己人
(担当:監修)
Option for the control of influenza II Option for the control of influenza II Elsevier Science Publishers B. V. 1993年1月
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261.
栄養士のための伝わるビジュアルデザイン入門
田中佐代子; 三輪佳宏; 小林麻己人
令和4年度 福祉保健局・東京都立病院機構 専門研修 職種職務専門研修「栄養士(病院・保健所)」 公益財団法人東京都福祉保健財団 招待有り
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262.
科学プレゼンテーション~研究者のためのビジュアルデザイン~
田中佐代子; 三輪, 佳宏; 小林麻己人
R4年度 農研機構 主任研究員研修 国立研究開発法人 農業・食品産業技術総合研究機構 招待有り
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263.
科学プレゼンテーション~研究者のためのビジュアルデザイン~
田中佐代子; 三輪, 佳宏; 小林麻己人
R4年度 農研機構 主任研究員研修 国立研究開発法人 農業・食品産業技術総合研究機構 招待有り
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264.
Disperse scatterer model of OCT and its application to design volumetric differential contrast imaging
Tomita, Kiriko; Makita, Shuichi; Fukutake, Naoki; Morishita, Rion; El-Sadek; Ibrahim G. Abd; Mukherjee, Pradipta; Lichtenegger, Antonia; Tamaoki, Junya; Bian, Lixuan; Kobayashi, Makoto; Mori, Tomoko; Matsusaka, Satoshi; Yasuno, Yoshiaki
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, Photonics West BiOS SPIE
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265.
Multiple scattering suppression by multi-focus averaging in Jones-matrix optical coherence tomography
Zhu, Lida; Makita, Shuichi; Lim, Yiheng; Tamaoki, Junya; Zhu, Yiqiang; Kobayashi, Makoto; Yasuno, Yoshiaki
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, Photonics West BiOS SPIE
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266.
Non-invasive and label-free zebrafish investigations using polarization-sensitive optical coherence tomography
Lichtenegger, Antonia; Tamaoki, Junya; Mukherjee, Pradipta; Licandro, Roxane; Zhu, Lida; Mori, Tomoko; Morishita, Rion; Bian, Lixuan; El-Sadek; Ibrahim G. Ab; Makita, Shuichi; Leskovar, Konrad; Matsusaka, Satoshi; Distel, Martin; Kobayashi, Makoto; Baumann, Bernhard; Yasuno, Yoshiaki
Label-free Biomedical Imaging and Sensing (LBIS) 2023, Photonics West BiOS SPIE
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267.
Volumetric differential contrast imaging by computationally augmented optical coherence tomography microscopy
Tomita, Kiriko; Makita, Shuichi; Fukutake, Naoki; Morishita, Rion; El-Sadek; Ibrahim G. Abd; Mukherjee, Pradipta; Lichtenegger, Antonia; Tamaoki, Junya; Bian, Lixuan; Kobayashi, Makoto; Mori, Tomoko; Matsusaka, Satoshi; Yasuno, Yoshiaki
Label-free Biomedical Imaging and Sensing (LBIS) 2023, Photonics West BiOS SPIE
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268.
Evaluation of scatterer density estimator for tissue phantom visualization of optical coherence tomography
Lichtenegger, Antonia; Mukherjee, Pradipta; Tamaoki, Junya; Zhu, Lida; Bian, Lixuan; Abd El-Sadek; Ibrahim; Makita, Shuichi; Leskovar, Konrad; Kobayashi, Makoto; Baumann, Bernhard; Yasuno, Yoshiaki
Optics and Photonics Japan
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269.
Multiple-scattering-noise reduction in Jones-matrix optical coherence tomography by focus-modulated averaging
Zhu, Lida; Makita, Shuichi; Lim, Yiheng; Tamaoki, Junya; Zhu, Yiqiang; Kobayashi, Makoto; Yasuno, Yoshiaki
Optics & Photonics Japan 2022 日本光学会
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270.
Differential contrast imaging by optical coherence tomography designed using new mathematical sample modeling
Tomita, Kiriko; Makita, Shuichi; Fukutake, Naoki; Morishita, Rion; El-Sadek; Ibrahim Abd; Mukherjee, Pradipta; Lichtenegger, Antonia; Tamaoki, Junya; Bian, Lixuan; Kobayashi, Makoto; Mori, Tomoko; Matsusaka, Satoshi; Yasuno, Yoshiaki
Optics & Photonics Japan 2022 日本光学会
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271.
Longitudinal xenograft zebrafish investigation using polarization-sensitive Jones-matrix optical coherence tomography
Lichtenegger, Antonia; Tamaoki, Junya; Mori, Tomoko; Mukherjee, Pradipta; Zhu, Lida; Bian, Lixuan; El-Sadek; Ibrahim Abd; Makita, Shuichi; Matsusaka, Satoshi; Kobayashi, Makoto; Baumann, Bernhard; Yasuno, Yoshiaki
Interferometry XXI, OPTICAL ENGINEERING + APPLICATIONS SPIE
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272.
In Vivo Investigation of a Tumor Xenograft Zebrafish Model Using Multicontrast Polarization-Sensitive Optical Coherence Tomography
Litchtenegger, Antonia; Tamaoki, Junya; Mukherjee, Pradipta; Mori, Tomoko; Zhu, Lida; Bian, Lixuan; El-Sadek; Ibrahim Abd; Makita, Shuichi; Matsusaka, Satoshi; Kobayashi, Makoto; Baumann, Bernhard; Yasuno, Yoshiaki
Optica Biophonics Congress: Biomedical Optics
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273.
多様な親電子性物質に応答するKeap1-Nrf2システムの感知機構
小林麻己人; 李麗; 岩本典子; 中島やえ子; 金子寛; 熊谷嘉人; 山本雅之
日本ケミカルバイオロジー研究会第3回年会
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274.
Mutation of histone demethylase Lsd1 in zebrafish leads to specific defects in hematopoiesis
Kobayashi;M; Takeuchi;M; Kaneko;H; Yamamoto;M; 小林, 麻己人
The 21st NAITO conference on Nuclear Dynamics and RNA [I]
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275.
A mutation in the histone demethylase gene lsd1 causes specific defects in zebrafish hematopoiesis
Takeuchi;M; Kaneko;H; Kobayashi-Osaki;M; Kobayashi;M; Yamamoto;M; 小林, 麻己人
8th International Conference on Zebrafish Development & Genetics
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276.
Activation of Nrf2 defense system relieves fatal ER stress caused by a genetic mutation in zebrafish
Tsujita;T; Li;L; Mukaigasa;K; Kobayashi;M; Yamamoto;M; 小林, 麻己人
8th International Conference on Zebrafish Development & Genetics
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277.
突然変異ゼブラフィッシュを用いた小胞体ストレス応答とNrf2 システムの解析
向笠勝貴; 辻田忠志; 李麗; 小林麻己人; 山本雅之
第14回小型魚類研究会
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278.
小胞体ストレスを自然発症する突然変異ゼブラフィッシュ
辻田忠志; 李麗; 向笠勝貴; 小林麻己人; 山本雅之
第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
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279.
A physiological study of ER stress using zebrafish mutants
Mukaigasa;K; Tsujita;T; Li;L; Kobayashi;M; Yamamoto;M; 小林, 麻己人
JSPS-DST Asian Academic Seminar 2008
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280.
Nrf2 activation by genetically induced endoplasmic reticulum stress in zebrafish
Mukaigasa;K; Tsujita;T; Li;L; Kobayashi;M; Yamamoto;M; 小林, 麻己人
International symposium on “Molecular mechanism of environmental response to food and oxygen III”
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1. 特願2021ー105594: 抗酸化剤
木元, 広実; 守谷, 直子; 小林, 麻己人
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