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木村健一

Kimura, Kenichi

生存ダイナミクス研究センター , 助教
Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA) , Assistant Professor

http://saggymouse.tara.tsukuba.ac.jp/

オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。

1. Novel Aortic Dissection Model Links Endothelial Dysfunction and Immune Infiltration Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi (+16 著者) Yanagisawa, Hiromi
Circulation research (2025)
2. Spatiotemporal dynamics of CD73 in mouse retina under physiological conditions ISHII, Ryutaro; Sakurai, Keisuke; Hosomi, Nao; Fleischmann, Bernd K. (+2 著者) Yanagisawa, Hiromi
bioRxiv (2025)
3. Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice Hossain; ASM Sakhawa; Clarin; Maria Thea (+17 著者) Yanagisawa, Hiromi
MATRIX BIOLOGY 135: 24 (2025)
4. descSPIM: an affordable and easy-to-build light-sheet microscope optimized for tissue clearing techniques Otomo, Kohei; Omura, Takaki; Nozawa, Yuki; Edwards (+41 著者) Susaki, Etsuo A
Nature communications 15: 4941 (2024) Semantic Scholar
5. A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi (+17 著者) Yanagisawa, Hiromi
Biorxiv (2024) Semantic Scholar
6. Bone marrow CD73+ mesenchymal stem cells display increased stemness in vitro and promote fracture healing in vivo Kenichi Kimura; Martin Breitbach; Frank A. Schildberg; Michael HesseBernd K. Fleischmann
Bone Reports 15: 101133 (2021) Semantic Scholar
7. Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy. Kenichi, Kimura; Astrid, Ooms; Kathrin, Graf-Riesen; Maithreyan, Kuppusamy (+20 著者) Michael, Hesse
Nature Communications (2021) Semantic Scholar
8. Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels Kenichi Kimura; Karina Ramirez; Tram Anh Vu Nguyen; Yoshito Yamashiro (+1 著者) Hiromi Yanagisawa
Scientific Reports 11: 8683 (2021) Semantic Scholar
9. Tetrahydroimidazo[1,2-a]pyrazine Derivatives: Synthesis and Evaluation As Gαq-Protein Ligands. Michael Gütschow; Jim Küppers; Tobias Benkel; Suvi Annala (+3 著者) Evi Kostenis
Chemistry (Weinheim an der Bergstrasse, Germany) (2020) Semantic Scholar
10. PECAM/eGFP transgenic mice for monitoring of angiogenesis in health and disease. Florian Winkler; Katia Herz; Sarah Rieck; Kenichi Kimura (+4 著者) Daniela Wenzel
Scientific reports 8: 17582 (2018) Semantic Scholar
11. Midbody Positioning and Distance Between Daughter Nuclei Enable Unequivocal Identification of Cardiomyocyte Cell Division in Mice. Michael Hesse; Michael Doengi; Alexandra Becker; Kenichi Kimura (+2 著者) Bernd K Fleischmann
Circulation research 123: 1039 (2018) Semantic Scholar
12. Overexpression of Cx43 in cells of the myocardial scar: Correction of post-infarct arrhythmias through heterotypic cell-cell coupling. Wilhelm Roell; Alexandra M Klein; Martin Breitbach; Torsten S Becker (+19 著者) Bernd K Fleischmann
Scientific reports 8: 7145 (2018) Semantic Scholar
13. In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche. Martin Breitbach; Kenichi Kimura; Tiago C Luis; Christopher J Fuegemann (+13 著者) Bernd K Fleischmann
Cell stem cell 22: 262 (2018) Semantic Scholar
14. Elevated Expression of Dkk-1 by Glucocorticoid Treatment Impairs Bone Regenerative Capacity of Adipose Tissue-Derived Mesenchymal Stem Cells. Toshiki Kato; Vuong Cat Khanh; Kazutoshi Sato; Kenichi Kimura (+4 著者) Osamu Ohneda
Stem cells and development 27: 85 (2018) Semantic Scholar
15. Increased Expression of EGR-1 in Diabetic Human Adipose Tissue-Derived Mesenchymal Stem Cells Reduces Their Wound Healing Capacity. Nhu-Thuy Trinh; Toshiharu Yamashita; Kinuko Ohneda; Kenichi Kimura (+2 著者) Osamu Ohneda
Stem cells and development 25: 760 (2016) Semantic Scholar
16. A Chemokine Receptor, CXCR4, Which Is Regulated by Hypoxia-Inducible Factor 2α, Is Crucial for Functional Endothelial Progenitor Cells Migration to Ischemic Tissue and Wound Repair. Tran Cam Tu; Masumi Nagano; Toshiharu Yamashita; Hiromi Hamada (+2 著者) Osamu Ohneda
Stem cells and development 25: 266 (2016) Semantic Scholar
17. Impaired expression of HIF-2α induces compensatory expression of HIF-1α for the recovery from anemia. Ikki Tsuboi; Toshiharu Yamashita; Masumi Nagano; Kenichi Kimura (+1 著者) Osamu Ohneda
Journal of cellular physiology 230: 1534 (2015) Semantic Scholar
18. Hypoxia-inducible factor-3α promotes angiogenic activity of pulmonary endothelial cells by repressing the expression of the VE-cadherin gene. Satomi Kobayashi; Toshiharu Yamashita; Kinuko Ohneda; Masumi Nagano (+3 著者) Osamu Ohneda
Genes to cells : devoted to molecular & cellular mechanisms 20: 224 (2015) Semantic Scholar
19. Dual functions of hypoxia-inducible factor 1 alpha for the commitment of mouse embryonic stem cells toward a neural lineage. Yang Zhao; Mami Matsuo-Takasaki; Ikki Tsuboi; Kenichi Kimura (+2 著者) Osamu Ohneda
Stem cells and development 23: 2143 (2014) Semantic Scholar
20. The role of CCL5 in the ability of adipose tissue-derived mesenchymal stem cells to support repair of ischemic regions. Kenichi Kimura; Masumi Nagano; Georgina Salazar; Toshiharu Yamashita (+5 著者) Osamu Ohneda
Stem cells and development 23: 488 (2014) Semantic Scholar

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1. 心臓木村, 健一; 柳沢裕美 (担当:分担執筆, 範囲:大動脈瘤への分子生物学的アプローチ)
日本医学出版 2022年6月

41. Investigation of the molecular pathogenesis of aortic dissection in new Fibrillin 1 mutant mice by synchrotron imaging and transcriptomics analysis Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Deleeuw, Violette; Kanki, Sachiko; Asano, Keiichi; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y.; Ozaki, Haruka; Yanagisawa, Hiromi
Tsukuba Global Science Week 2024
42. Role of CD73-lineage cells in articular cartilage degeneration and remodeling in osteoarthritis Hosomi, Nao; Matsumiya, Marina; Yanagisawa, Hiromi; Kimura, Kenichi
Tsukuba Global Science Week 2024
43. Converting one differentiated cell identity into another: Insights from Drosophila enteroendocrine cells Qian, Qingyin; Hayashi, Makoto; Nagai, Hiroki; Kimura, Ken-ichi; Kobayashi, Satoru; Yanagisawa, Hiromi; Nakajima, Yuichiro; NIWA, Ryusuke
The 16th Japanese Drosophila Research Conference (JDRC16)
44. 新規Fibrillin-1点変異マウスモデルを⽤いた⼤動脈解離発症機序の解明木村, 健一
第10回MatriCellフォーラム
45. 新規Fibrillin-1点変異マウスモデルを用いた大動脈解離におけるメカノセンシング機構の解明本山, 絵理; 木村, 健一; Maria, Thea Rane; Dela Cruz Clarin; 浅野, 恵一; 神吉, 佐智子; 柳沢, 裕美
第56回日本結合組織学会学術大会
46. Investigation of the molecular pathogenesis of aortic dissection in new Fibrillin 1 mutant mice by synchrotron imaging and transcriptomics analysis Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Deleeuw, Violette; Kanki, Sachiko; Asano, Keiichi; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Yanagisawa, Hiromi
第56回日本結合組織学会学術大会
47. Fibrillin-1 G234D mutation links mouse skin tightness to elastic fiber defects and collagen cross-linking Hossain; ASM Sakhawa; Cruz, Maria Thea Rane Dela; Kimura, Kenichi; Taga, Yuki; Uto, Koichiro; Yamagishi, Ayana; Motoyama, Eri; Mizuno, Kazunori; Nakamura, Chikashi; Asano, Keiichi; Ohtsuki, Sumio; Nakamura, Tomoyuki; Kanki, Sachiko; Raja, Erna; Yanagisawa, Hiromi
第56回日本結合組織学会学術大会
48. Nanoparticles as a potential therapeutic tool for targeting M1 macrophages in Aortic Dissection Cruz, Maria Thea Rane Dela; Motoyama, Eri; Ahmed, Nabil; Uto, Koichiro; Kanki, Sachiko; Kimura, Kenichi; Asano, Keiichi; Ebara, Mitsuhiro; Yanagisawa, Hiromi
第56回日本結合組織学会学術大会
49. A Smart Nanofiber-based Therapeutic Approach for Aortic Dissection by Targeting Sympathetic Innervation LI, Kai; Kimura, Kenichi; Motoyama, Eri; Fujisawa, Nanami; Chen, Lili; Yanagisawa, Hiromi; Ebara, Mitsuhiro
第56回日本結合組織学会学術大会
50. CELL LINEAGE ANALYSIS OF CD73-POSITIVE CELLS IN OSTEOCHONDRAL TISSUE Kimura, Kenichi; Ishi, Ryutaro; Yanagisawa, Hiromi
The International Society for Stem Cell Research 2024
51. A Smart Nanofiber-based Therapeutic Approach for Aortic Dissection by Targeting Sympathetic Innervation LI, Kai; Chen, Lili; Fujisawa, Nanami; Kimura, Kenichi; Motoyama, Eri; Yanagisawa, Hiromi; Ebara, Mitsuhiro
The 40th annual meeting of JSDDS
52. Treatment for Aortic Dissection Using Nanoparticles to Target M1 Macrophages. Clarin; M.T.R.D.C; Motoyama, E; Nabil, A; Kanki, S; Kimura, Kenichi; Ebara, Mitsuhiro; Yanagisawa, H
つくば医工連携フォーラム2024
53. Investigation of the role of macrophages in Fbn1 mutant mice and development of therapeutic strategy for aortic dissection. Clarin; M.T.R.D.C; Motoyama, Eri; A, Nabil; Kanki, Sachiko; Kimura, Kenichi; M, Ebara; Yanagisawa, Hiromi
the annual Tsukuba Global Science Week (TGSW) 2023
54. Development of nanoparticles to induce M1-to-M2 switch as a treatment for aortic dissection in Fbn1 mutant mice. Clarin; M.T.R.D.C; E., Motoyama; A., Nabil; S., Kanki; Kimura, Kenichi; Ebara, Mitsuhiro; H., Yanagisawa
World Biomaterials Congress
55. Development of nanoparticles to induce M1-to-M2 switch as a treatment for aortic dissection in Fbn1 mutant mice. Clarin; M.T.R.D.C; E., Motoyama; A., Nabil; S., Kanki; Uto, Koichiro; Kimura, Kenichi; Ebara, Mitsuhiro; H., Yanagisawa
International Vascular Biology Meeting 2024
56. Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection. Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi; Sheikh, Md Al Amin; Deleeuw, Violette; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Yanagisawa, Hiromi
International Vascular Biology Meeting 2024
57. 骨軟骨組織の維持・再生に関わる間葉系幹細胞の同定木村, 健一
第23回日本再生医療学会総会
58. Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Deleeuw, Violette; Kanki, Sachiko; Asano, Keiichi; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Ozaki, Haruka; Yanagisawa, Hiromi
the annual Tsukuba Global Science Week (TGSW) 2023
59. A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes Tight Skin Phenotype ASM; Sakhawat Hossain; Maria, Thea Rane; Dela Cruz; Koichiro, Uto; Eri, Motoyama; Sumio, Ohtsuki; Keiichi, Asano; Kenichi, Kimura; Yuki, Taga; Kazunori, Mizuno; Tomoyuki, Nakamura; Sachiko, Kanki; Erna, Raja; Hiromi, Yanagisawa
第7回エラスチン・関連分子研究会学術集会
60. 新規Fibrillin-1点変異マウスモデルを⽤いた⼤動脈解離発症機序の解明木村, 健一
第1回大動脈研究会