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木村健一

Kimura, Kenichi

生存ダイナミクス研究センター , 准教授
Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA) , Associate Professor

http://saggymouse.tara.tsukuba.ac.jp/

1. Circadian regulation of bladder capacity and extracellular matrix variation independent of central clock–driven behavioral rhythms Suzuki, Shuhei; Negoro, Hiromitsu; Nonaka, Haruna; Chihara, Ichiro (+5 著者) Nishiyama, Hiroyuki
Communications biology (2026)
2. Structural and transcriptomic alterations underlying the progression of aortic dissection in Fbn1G234D/G234D mice Sheikh, Md Al Amin; KIMURA, Kenichi; Motoyama, Eri; Asano, Keiichi (+12 著者) Yanagisawa, Hiromi
Scientific Reports (2026)
3. Blockage of autophagy causes severe skeletal muscle disruption in a mouse model for myofibrillar myopathy 6 Filippi, Kerstin; Graf-Riesen, Kathrin; Kuppusamy, Maithreyan; Unger, Andreas (+14 著者) Hesse, Michael
Nature communications 17: (2026) Semantic Scholar
4. The epidermal stem cell-supporting matricellular protein fibulin 7 modulates skin inflammatory response in a psoriasis model Erna, Raja; Tomoko, Machida; Narenmandula; Karolina, Edlund (+9 著者) Hiromi, Yanagisawa
Biorxiv (2026)
5. Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut Qian, Qingyin; Nagai, Hiroki; Sanaki, Yuya; Hayashi, Makoto (+2 著者) Niwa, Ryusuke
Development (Cambridge, England) 153: dev205225 (2026)
6. Spatiotemporal dynamics of CD73 in mouse retina under physiological conditions Ishii, Ryutaro; Sakurai, Keisuke; Hosomi, Nao; Fleischmann, Bernd K. (+2 著者) Yanagisawa, Hiromi
Development (Cambridge, England) 153: (2026) Semantic Scholar
7. Skeletal muscle disruption and mitochondrial dysfunction cause BAG3P209L-myofibrillar myopathy Filippi, K.; Graf-Riesen, K.; Kuppusamy, M.; Unger, A. (+10 著者) Hesse, M.
ACTA PHYSIOLOGICA 241: (2025)
8. Novel Aortic Dissection Model Links Endothelial Dysfunction and Immune Infiltration Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi (+16 著者) Yanagisawa, Hiromi
Circulation research 137: 26 (2025) Semantic Scholar
9. Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice Hossain; ASM Sakhawa; Clarin; Maria Thea (+17 著者) Yanagisawa, Hiromi
MATRIX BIOLOGY 135: 24 (2025)
10. descSPIM: an affordable and easy-to-build light-sheet microscope optimized for tissue clearing techniques Otomo, Kohei; Omura, Takaki; Nozawa, Yuki; Edwards (+41 著者) Susaki, Etsuo A.
Nature communications 15: 4941 (2024) Semantic Scholar
11. A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi (+17 著者) Yanagisawa, Hiromi
Biorxiv (2024) Semantic Scholar
12. Bone marrow CD73+ mesenchymal stem cells display increased stemness in vitro and promote fracture healing in vivo Kenichi Kimura; Martin Breitbach; Frank A. Schildberg; Michael HesseBernd K. Fleischmann
Bone Reports 15: 101133 (2021) Semantic Scholar
13. Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy. Kenichi, Kimura; Astrid, Ooms; Kathrin, Graf-Riesen; Maithreyan, Kuppusamy (+20 著者) Michael, Hesse
Nature Communications (2021) Semantic Scholar
14. Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels Kenichi Kimura; Karina Ramirez; Tram Anh Vu Nguyen; Yoshito Yamashiro (+1 著者) Hiromi Yanagisawa
Scientific Reports 11: 8683 (2021) Semantic Scholar
15. Tetrahydroimidazo[1,2-a]pyrazine Derivatives: Synthesis and Evaluation As Gαq-Protein Ligands. Michael Gütschow; Jim Küppers; Tobias Benkel; Suvi Annala (+3 著者) Evi Kostenis
Chemistry (Weinheim an der Bergstrasse, Germany) (2020) Semantic Scholar
16. PECAM/eGFP transgenic mice for monitoring of angiogenesis in health and disease. Florian Winkler; Katia Herz; Sarah Rieck; Kenichi Kimura (+4 著者) Daniela Wenzel
Scientific reports 8: 17582 (2018) Semantic Scholar
17. Midbody Positioning and Distance Between Daughter Nuclei Enable Unequivocal Identification of Cardiomyocyte Cell Division in Mice. Michael Hesse; Michael Doengi; Alexandra Becker; Kenichi Kimura (+2 著者) Bernd K Fleischmann
Circulation research 123: 1039 (2018) Semantic Scholar
18. Overexpression of Cx43 in cells of the myocardial scar: Correction of post-infarct arrhythmias through heterotypic cell-cell coupling. Wilhelm Roell; Alexandra M Klein; Martin Breitbach; Torsten S Becker (+19 著者) Bernd K Fleischmann
Scientific reports 8: 7145 (2018) Semantic Scholar
19. In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche. Martin Breitbach; Kenichi Kimura; Tiago C Luis; Christopher J Fuegemann (+13 著者) Bernd K Fleischmann
Cell stem cell 22: 262 (2018) Semantic Scholar
20. Elevated Expression of Dkk-1 by Glucocorticoid Treatment Impairs Bone Regenerative Capacity of Adipose Tissue-Derived Mesenchymal Stem Cells. Toshiki Kato; Vuong Cat Khanh; Kazutoshi Sato; Kenichi Kimura (+4 著者) Osamu Ohneda
Stem cells and development 27: 85 (2018) Semantic Scholar

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1. 心臓木村, 健一; 柳沢裕美 (担当:分担執筆, 範囲:大動脈瘤への分子生物学的アプローチ)
日本医学出版 2022年6月

41. マルファン症候群モデルマウスを用いた胸部大動脈瘤破裂関連因子の探索杉山, 夏緒里; 佐藤, 由弥; 安藤, 正浩; 松永, 浩子; 木村, 健一; 片岡, 孝介; 川内, 聡子; 有田, 誠; 柳沢, 裕美; 竹山, 春子
第9回エラスチン･関連分子研究会学術集会
42. Synchrotron Imaging and Transcriptomics Reveal 3D Remodeling and Molecular Pathogenesis of Aortic Dissection in Fbn1G234D/G234D Novel Mutant Mice Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Asano, Keiichi; Deleeuw, Violette; Kanki, Sachiko; Ryutaro, Ishii; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y.; Ozaki, Haruka; Yanagisawa, Hiromi
MBSJ 2025
43. Xrp1 promotes enteroendocrine cell plasticity in the regenerating Drosophila midgut Qian, Qingyin; Nagai, Hiroki; Sanaki, Yuya; Makoto, Hayashi; Kimura, Kenichi; Nakajima, Yuichiro; NIWA, Ryusuke
28th European Drosophila Research Conference
44. 骨軟骨組織の維持・再生に関わる間葉系幹細胞の同定木村, 健一
第11回MatriCellフォーラム招待有り
45. Novel Aortic Dissection Model Links Endothelial Dysfunction and Immune Infiltration KIMURA, Kenichi
TRR259 Seminar 招待有り
46. A novel genetic mouse model of aortic dissection linking endothelial dysfunction and immune cell infiltration. KIMURA, Kenichi
Elastin, Elastic Fibers and Microfibrils, Gordon Research Conference
47. A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta KIMURA, Kenichi
The 2nd internatinal symposium for Research Unit "Peripheral Central Interaction in Stress"
48. 大動脈瘤・解離における免疫細胞のダイナミクス：新規マルファン症候群マウスモデルからの知見浅野, 恵一; 本山絵理; 神吉佐智子; 木村健一; 柳沢, 裕美
第57回日本結合組織学会学術大会
49. 骨髄ニッチにおけるミクロフィブリルを介した造血制御機構の解明木村, 健一; 細見奈生; 本山絵理; 神吉佐智子; 柳沢裕美
第57回日本結合組織学会学術大会
50. A Smart Nanofiber-based Therapeutic Approach for Aortic Dissection by Targeting Sympathetic Innervation Kai, LI; Kenichi, Kimura; Eri, Motoyama; Nanami, Fujisawa; Lili, Chen; Hiromi, Yanagisawa; Mitsuhiro, Ebara
第57回日本結合組織学会学術大会
51. Elucidating the Role of Anti-aging Matrix Fibulin 7 in Skin Inflammatory Disease Psoriasis ERNA, Raja; Watanabe, Yukihide; Kimura, Kenichi; Yanagisawa, Hiromi
日本研究皮膚科学会第49回年次学術大会・総会（49th JSID）
52. Transformation of enteroendocrine cell identity by the stress-inducible transcription factor Xrp1 Qian, Qingyin; Hayashi, Makoto; Nagai, Hiroki; Sanaki, Yuya; Kimura, Kenichi; Kobayashi, Satoru; Nakajima, Yuichiro; NIWA, Ryusuke
66th Annual Drosophila Research Conference
53. Anti-inflammatory Nanoparticles as Potential Treatment for Aortic Dissection Clarin; M.T.R.D.C.; Motoyama, Eri; A., Nabil; Kanki, Sachiko; Uto, Koichiro; Kimura, Kenichi; H., Yanagisawa; Ebara, Mitsuhiro
つくば医工連携フォーラム2025
54. A stress-responsive transcriptional factor drives fate conversion of enteroendocrine cells in Drosophila melanogaster Qian, Qingyin; Hayashi, Makoto; Nagai, Hiroki; Kimura, Ken-ichi; Kobayashi, Satoru; Nakajima, Yuichiro; NIWA, Ryusuke
第47回日本分子生物学会年会
55. Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection. Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi; Sheikh, Md Al Amin; Deleeuw, Violette; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y.; Yanagisawa, Hiromi
第47回日本分子生物学会年会
56. 軟骨組織におけるCD73陽性細胞の細胞系譜解析松宮, 舞奈; 細見奈生; 柳沢裕美; 木村健一
第47回日本分子生物学会年会
57. 骨髄ニッチにおけるミクロフィブリルを介した造血制御機構の解明木村, 健一; 本山絵理; 神吉佐知子; 柳沢裕美
第8回エラスチン・関連分子研究会
58. フィブリリン１遺伝子変異による大動脈解離病態に関わる血管内皮細胞の機能解析本山絵理; 木村, 健一; 浅野恵一; 神吉佐知子; 中邨智之; 柳沢裕美
第8回エラスチン・関連分子研究会
59. 遺伝性胸部大動脈疾患におけるメカノトランスダクション異常柳沢裕美; 木村健一; 本山絵理; 浅野恵一; 神吉佐知子
CVMW 2024
60. Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection. Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi; Sheikh, Md Al Amin; Deleeuw, Violette; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y.; Yanagisawa, Hiromi
CVMW 2024