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木村健一

Kimura, Kenichi

生存ダイナミクス研究センター , 助教
Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA) , Assistant Professor

http://saggymouse.tara.tsukuba.ac.jp/

オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。

1. Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice Hossain; ASM Sakhawa; Clarin; Maria Thea (+17 著者) Yanagisawa, Hiromi
MATRIX BIOLOGY 135: 24 (2024)
2. descSPIM: an affordable and easy-to-build light-sheet microscope optimized for tissue clearing techniques Otomo, Kohei; Omura, Takaki; Nozawa, Yuki; Edwards (+41 著者) Susaki, Etsuo A
Nature communications 15: 4941 (2024) Semantic Scholar
3. A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi (+17 著者) Yanagisawa, Hiromi
Biorxiv (2024) Semantic Scholar
4. Bone marrow CD73+ mesenchymal stem cells display increased stemness in vitro and promote fracture healing in vivo Kenichi Kimura; Martin Breitbach; Frank A. Schildberg; Michael HesseBernd K. Fleischmann
Bone Reports 15: 101133 (2021) Semantic Scholar
5. Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy. Kenichi, Kimura; Astrid, Ooms; Kathrin, Graf-Riesen; Maithreyan, Kuppusamy (+20 著者) Michael, Hesse
Nature Communications (2021) Semantic Scholar
6. Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels Kenichi Kimura; Karina Ramirez; Tram Anh Vu Nguyen; Yoshito Yamashiro (+1 著者) Hiromi Yanagisawa
Scientific Reports 11: 8683 (2021) Semantic Scholar
7. Tetrahydroimidazo[1,2-a]pyrazine Derivatives: Synthesis and Evaluation As Gαq-Protein Ligands. Michael Gütschow; Jim Küppers; Tobias Benkel; Suvi Annala (+3 著者) Evi Kostenis
Chemistry (Weinheim an der Bergstrasse, Germany) (2020) Semantic Scholar
8. PECAM/eGFP transgenic mice for monitoring of angiogenesis in health and disease. Florian Winkler; Katia Herz; Sarah Rieck; Kenichi Kimura (+4 著者) Daniela Wenzel
Scientific reports 8: 17582 (2018) Semantic Scholar
9. Midbody Positioning and Distance Between Daughter Nuclei Enable Unequivocal Identification of Cardiomyocyte Cell Division in Mice. Michael Hesse; Michael Doengi; Alexandra Becker; Kenichi Kimura (+2 著者) Bernd K Fleischmann
Circulation research 123: 1039 (2018) Semantic Scholar
10. Overexpression of Cx43 in cells of the myocardial scar: Correction of post-infarct arrhythmias through heterotypic cell-cell coupling. Wilhelm Roell; Alexandra M Klein; Martin Breitbach; Torsten S Becker (+19 著者) Bernd K Fleischmann
Scientific reports 8: 7145 (2018) Semantic Scholar
11. In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche. Martin Breitbach; Kenichi Kimura; Tiago C Luis; Christopher J Fuegemann (+13 著者) Bernd K Fleischmann
Cell stem cell 22: 262 (2018) Semantic Scholar
12. Elevated Expression of Dkk-1 by Glucocorticoid Treatment Impairs Bone Regenerative Capacity of Adipose Tissue-Derived Mesenchymal Stem Cells. Toshiki Kato; Vuong Cat Khanh; Kazutoshi Sato; Kenichi Kimura (+4 著者) Osamu Ohneda
Stem cells and development 27: 85 (2018) Semantic Scholar
13. Increased Expression of EGR-1 in Diabetic Human Adipose Tissue-Derived Mesenchymal Stem Cells Reduces Their Wound Healing Capacity. Nhu-Thuy Trinh; Toshiharu Yamashita; Kinuko Ohneda; Kenichi Kimura (+2 著者) Osamu Ohneda
Stem cells and development 25: 760 (2016) Semantic Scholar
14. A Chemokine Receptor, CXCR4, Which Is Regulated by Hypoxia-Inducible Factor 2α, Is Crucial for Functional Endothelial Progenitor Cells Migration to Ischemic Tissue and Wound Repair. Tran Cam Tu; Masumi Nagano; Toshiharu Yamashita; Hiromi Hamada (+2 著者) Osamu Ohneda
Stem cells and development 25: 266 (2016) Semantic Scholar
15. Impaired expression of HIF-2α induces compensatory expression of HIF-1α for the recovery from anemia. Ikki Tsuboi; Toshiharu Yamashita; Masumi Nagano; Kenichi Kimura (+1 著者) Osamu Ohneda
Journal of cellular physiology 230: 1534 (2015) Semantic Scholar
16. Hypoxia-inducible factor-3α promotes angiogenic activity of pulmonary endothelial cells by repressing the expression of the VE-cadherin gene. Satomi Kobayashi; Toshiharu Yamashita; Kinuko Ohneda; Masumi Nagano (+3 著者) Osamu Ohneda
Genes to cells : devoted to molecular & cellular mechanisms 20: 224 (2015) Semantic Scholar
17. Dual functions of hypoxia-inducible factor 1 alpha for the commitment of mouse embryonic stem cells toward a neural lineage. Yang Zhao; Mami Matsuo-Takasaki; Ikki Tsuboi; Kenichi Kimura (+2 著者) Osamu Ohneda
Stem cells and development 23: 2143 (2014) Semantic Scholar
18. The role of CCL5 in the ability of adipose tissue-derived mesenchymal stem cells to support repair of ischemic regions. Kenichi Kimura; Masumi Nagano; Georgina Salazar; Toshiharu Yamashita (+5 著者) Osamu Ohneda
Stem cells and development 23: 488 (2014) Semantic Scholar
19. Functional endothelial progenitor cells selectively recruit neurovascular protective monocyte-derived F4/80(+) /Ly6c(+) macrophages in a mouse model of retinal degeneration. Shinichi Fukuda; Masumi Nagano; Toshiharu Yamashita; Kenichi Kimura (+6 著者) Osamu Ohneda
Stem cells (Dayton, Ohio) 31: 2149 (2013) Semantic Scholar
20. Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation. Keiko Akimoto; Kenichi Kimura; Masumi Nagano; Shingo Takano (+2 著者) Osamu Ohneda
Stem cells and development 22: 1370 (2013) Semantic Scholar

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1. 心臓木村, 健一; 柳沢裕美 (担当:分担執筆, 範囲:大動脈瘤への分子生物学的アプローチ)
日本医学出版 2022年6月

41. Investigation of the molecular pathogenesis of aortic dissection in new Fibrillin 1 mutant mice by synchrotron imaging and transcriptomics analysis Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Deleeuw, Violette; Kanki, Sachiko; Asano, Keiichi; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Yanagisawa, Hiromi
第56回日本結合組織学会学術大会
42. Fibrillin-1 G234D mutation links mouse skin tightness to elastic fiber defects and collagen cross-linking Hossain; ASM Sakhawa; Cruz, Maria Thea Rane Dela; Kimura, Kenichi; Taga, Yuki; Uto, Koichiro; Yamagishi, Ayana; Motoyama, Eri; Mizuno, Kazunori; Nakamura, Chikashi; Asano, Keiichi; Ohtsuki, Sumio; Nakamura, Tomoyuki; Kanki, Sachiko; Raja, Erna; Yanagisawa, Hiromi
第56回日本結合組織学会学術大会
43. Nanoparticles as a potential therapeutic tool for targeting M1 macrophages in Aortic Dissection Cruz, Maria Thea Rane Dela; Motoyama, Eri; Ahmed, Nabil; Uto, Koichiro; Kanki, Sachiko; Kimura, Kenichi; Asano, Keiichi; Ebara, Mitsuhiro; Yanagisawa, Hiromi
第56回日本結合組織学会学術大会
44. A Smart Nanofiber-based Therapeutic Approach for Aortic Dissection by Targeting Sympathetic Innervation LI, Kai; Kimura, Kenichi; Motoyama, Eri; Fujisawa, Nanami; Chen, Lili; Yanagisawa, Hiromi; Ebara, Mitsuhiro
第56回日本結合組織学会学術大会
45. CELL LINEAGE ANALYSIS OF CD73-POSITIVE CELLS IN OSTEOCHONDRAL TISSUE Kimura, Kenichi; Ishi, Ryutaro; Yanagisawa, Hiromi
The International Society for Stem Cell Research 2024
46. A Smart Nanofiber-based Therapeutic Approach for Aortic Dissection by Targeting Sympathetic Innervation LI, Kai; Chen, Lili; Fujisawa, Nanami; Kimura, Kenichi; Motoyama, Eri; Yanagisawa, Hiromi; Ebara, Mitsuhiro
The 40th annual meeting of JSDDS
47. Treatment for Aortic Dissection Using Nanoparticles to Target M1 Macrophages. Clarin; M.T.R.D.C; Motoyama, E; Nabil, A; Kanki, S; Kimura, Kenichi; Ebara, Mitsuhiro; Yanagisawa, H
つくば医工連携フォーラム2024
48. Investigation of the role of macrophages in Fbn1 mutant mice and development of therapeutic strategy for aortic dissection. Clarin; M.T.R.D.C; Motoyama, Eri; A, Nabil; Kanki, Sachiko; Kimura, Kenichi; M, Ebara; Yanagisawa, Hiromi
the annual Tsukuba Global Science Week (TGSW) 2023
49. Development of nanoparticles to induce M1-to-M2 switch as a treatment for aortic dissection in Fbn1 mutant mice. Clarin; M.T.R.D.C; E., Motoyama; A., Nabil; S., Kanki; Kimura, Kenichi; Ebara, Mitsuhiro; H., Yanagisawa
World Biomaterials Congress
50. Development of nanoparticles to induce M1-to-M2 switch as a treatment for aortic dissection in Fbn1 mutant mice. Clarin; M.T.R.D.C; E., Motoyama; A., Nabil; S., Kanki; Uto, Koichiro; Kimura, Kenichi; Ebara, Mitsuhiro; H., Yanagisawa
International Vascular Biology Meeting 2024
51. Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection. Kimura, Kenichi; Motoyama, Eri; Kanki, Sachiko; Asano, Keiichi; Sheikh, Md Al Amin; Deleeuw, Violette; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Yanagisawa, Hiromi
International Vascular Biology Meeting 2024
52. 骨軟骨組織の維持・再生に関わる間葉系幹細胞の同定木村, 健一
第23回日本再生医療学会総会
53. Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Deleeuw, Violette; Kanki, Sachiko; Asano, Keiichi; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Ozaki, Haruka; Yanagisawa, Hiromi
the annual Tsukuba Global Science Week (TGSW) 2023
54. A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes Tight Skin Phenotype ASM; Sakhawat Hossain; Maria, Thea Rane; Dela Cruz; Koichiro, Uto; Eri, Motoyama; Sumio, Ohtsuki; Keiichi, Asano; Kenichi, Kimura; Yuki, Taga; Kazunori, Mizuno; Tomoyuki, Nakamura; Sachiko, Kanki; Erna, Raja; Hiromi, Yanagisawa
第7回エラスチン・関連分子研究会学術集会
55. 新規Fibrillin-1点変異マウスモデルを⽤いた⼤動脈解離発症機序の解明木村, 健一
第1回大動脈研究会
56. Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis Sheikh, Md Al Amin; Kimura, Kenichi; Motoyama, Eri; Deleeuw, Violette; Kanki, Sachiko; Asano, Keiichi; Sips, Patrick; Backer, Julie De; Sakai, Lynn Y; Ozaki, Haruka; Yanagisawa, Hiromi
第7回日本循環器学会基礎研究フォーラム（BCVR）
57. 骨髄微小環境におけるCD73陽性細胞の細胞系譜解析木村, 健一; Bernd, Fleischmann; 柳沢, 裕美
第46回日本分子生物学会年会
58. Maintaining differentiated cell identity during aging -- insights from Drosophila enteroendocrine cells Qian, Qingyin; Hayashi, Makoto; Kimura, Ken-ichi; Yanagisawa, Hiromi; Niwa, Ryusuke
第46回日本分子生物学会年会
59. Multimodal imaging to identify pre-signals for acute aortic dissection by using Marfan syndrome model mouse Sugiyama, Kaori; Ando, Masahiro; Wagatsuma, Ryota; Matsunaga, Hiroko; Uchino, Haruki; Kimura, Kenichi; Ramirez, Francesco; Schenke-Layland, Katja; Arita, Makoto; Yanagisawa, Hiromi; Takeyama, Haruko
Basic Cardiovascular Sciences Scientific Sessions 2024
60. Investigation of the molecular mechanism of BAV-associated aortopathy Liu, Chang; Tokunaga, Chiho; Sugiyama, Kaori; Kimura, Kenichi; Tsukda, Toru; Kato, Hideyuki; Matsubara, Muneaki; Osaka, Motoo; Sakamoto, Hiroaki; Matsunaga, Hiroko; Takeyama, Haruko; Yanagisawa, Hiromi; Hiramatsu, Yuji
The 76th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery