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家田 真樹
ALUMNI
2026年6月現在、筑波大学が主たる所属機関ではありません
Ieda, Masaki
筑波大学 University of Tsukuba

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慢性心不全を心筋ダイレクトリプログラミングで改善〜新しい心臓再生医療に向けて〜
2022-12-12
家田 真樹

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マウスの心筋は心筋直接リプログラミングで心臓線維芽細胞から真に再生することを証明
2021-06-29
家田 真樹
オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
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1.
Response by Yamada et al to Letter Regarding Article, "Cardiac Reprogramming and Gata4 Overexpression Reduce Fibrosis and Improve Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction".
Yu Yamada; Taketaro Sadahiro; Masaki Ieda
Circulation 152: 1320 (2025) Semantic Scholar
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2.
Shortening and optimization of MEF2C and GATA4 promote cardiac reprogramming.
Seiichiro Honda; Taketaro Sadahiro; Yuto Abe; Yu Yamada (+8 著者) Masaki Ieda
Biochemical and biophysical research communications 781: 152511 (2025) Semantic Scholar
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3.
Heart failure-specific cardiac fibroblasts contribute to cardiac dysfunction via the MYC–CXCL1–CXCR2 axis
Jin Komuro; Hisayuki Hashimoto; Toshiomi Katsuki; Dai Kusumoto (+16 著者) Masaki Ieda
Nature Cardiovascular Research 4: 1135 (2025) Semantic Scholar
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4.
Inhibition of Scarb1 on Endothelial Cells Attenuates Pressure Overload-induced Heart Failure Progression
Toshiomi Katsuki; Dai Kusumoto; Yohei Akiba; Mai Kimura (+12 著者) Masaki Ieda
JACC: Basic to Translational Science 101308 (2025) Semantic Scholar
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5.
Sipa1 Drives a Maladaptive Fibroblast-Myeloid Axis After Myocardial Infarction.
Seien Ko; Xueyuan Liu; Yurika Taniguchi; Genki Ichihara (+10 著者) Masaki Ieda
Circulation research 137: 533 (2025) Semantic Scholar
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6.
CD300a immunoreceptor regulates ischemic tissue damage and adverse remodeling in the mouse heart and kidney
Nanako Nishiyama; Hitoshi Koizumi; Chigusa Nakahashi-Oda; Satoshi Fujiyama (+11 著者) Akira Shibuya
Journal of Clinical Investigation (2025) Semantic Scholar
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7.
Serine synthesis pathway regulates cardiac differentiation from human pluripotent stem cells
Tomohiko C. Umei; Shugo Tohyama; Yuika Morita-Umei; Manami Katoh (+12 著者) Masaki Ieda
iScience 112843 (2025) Semantic Scholar
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8.
Exercise hemodynamic evaluation in the management of dasatinib-related pulmonary arterial hypertension: a case report
Shuhei Yamashita; Takahiro Hiraide; Yasuyuki Shiraishi; Yoshinori Katsumata (+6 著者) Masaki Ieda
Journal of Medical Case Reports 19: (2025) Semantic Scholar
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9.
Loeys-Dietz Syndrome(LDS), One of Systemic Connective Tissue Disease, may be Associated with Low Pulse Wave Velocity/Cardio Ankle Vascular Index(PWV/CAVI)(タイトル和訳中)
山川 裕之; 山岸 敬幸; 高石 官均; 家田 真樹
日本循環器学会学術集会抄録集 89回: CRDJ23 (2025)
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10.
Cardiac Reprogramming and Gata4 Overexpression Reduce Fibrosis and Improve Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction
Yu Yamada; Taketaro Sadahiro; Koji Nakano; Seiichiro Honda (+17 著者) Masaki Ieda
Circulation 151: 379 (2025) Semantic Scholar
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11.
Heart Regeneration for Clinical Application.
Hidenori Tani; Masaki Ieda
Internal medicine (Tokyo, Japan) (2024) Semantic Scholar
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12.
Diagnostic Value of Combined Light and Electron Microscopic Examination in Endomyocardial Biopsy in Patients with Cardiac Amyloidosis.
Masayoshi Yamamoto; Yu Yamada; Taketaro Sadahiro; Kimi Sato (+3 著者) Tomoko Ishizu
The Canadian journal of cardiology (2024) Semantic Scholar
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13.
Metabolic changes of human induced pluripotent stem cell-derived cardiomyocytes and teratomas after transplantation
Yusuke Soma; Shugo Tohyama; Akiko Kubo; Tomoteru Yamasaki (+18 著者) Masaki Ieda
iScience 27: 111234 (2024) Semantic Scholar
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14.
Development of adeno-associated viral vectors targeting cardiac fibroblasts for efficient in vivo cardiac reprogramming
Koji Nakano; Taketaro Sadahiro; Ryo Fujita; Mari Isomi (+6 著者) Masaki Ieda
Stem Cell Reports (2024) Semantic Scholar
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15.
Metabolic remodeling and calcium handling abnormality in induced pluripotent stem cell-derived cardiomyocytes in dilated phase of hypertrophic cardiomyopathy with MYBPC3 frameshift mutation.
Haruka Mori; Dongzhu Xu; Yuzuno Shimoda; Zixun Yuan (+7 著者) Nobuyuki Murakoshi
Scientific reports 14: 15422 (2024) Semantic Scholar
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16.
Impact of cancer in patients with aortic stenosis undergoing transcatheter aortic valve replacement: A systematic review and meta-analysis.
Takumi Osawa; Kazuko Tajiri; Tomoya Hoshi; Masaki IedaTomoko Ishizu
International journal of cardiology. Heart & vasculature 52: 101410 (2024) Semantic Scholar
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17.
An inherited life-threatening arrhythmia model established by screening randomly mutagenized mice.
Yuta Okabe; Nobuyuki Murakoshi; Nagomi Kurebayashi; Hana Inoue (+16 著者) Masashi Yanagisawa
Proceedings of the National Academy of Sciences of the United States of America 121: e2218204121 (2024) Semantic Scholar
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18.
Successful Treatment of Malignant Lymphoma Following Transcatheter Aortic Valve Replacement: A Case Report.
Takumi Osawa; Kazuko Tajiri; Tomoya Hoshi; Masaki IedaTomoko Ishizu
Internal medicine (Tokyo, Japan) (2024) Semantic Scholar
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19.
Trends in Unplanned Admissions of Patients With Adult Congenital Heart Disease Based on the Japanese Registry of All Cardiac and Vascular Diseases-Diagnosis Procedure Combination Study.
Ayako Kuraoka; Tomoko Ishizu; Michikazu Nakai; Yoko Sumita (+3 著者) Masaki Ieda
Circulation journal : official journal of the Japanese Circulation Society 88: 83 (2023) Semantic Scholar
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20.
Longitudinal Changes in Natriuretic Peptides and Reverse Cardiac Remodeling in Patients with Heart Failure Treated with Sacubitril/Valsartan Across the Left Ventricular Ejection Traction Spectrum.
Masayoshi Yamamoto; Tomoko Ishizu; Kimi Sato; Kentaro Minami (+4 著者) Masaki Ieda
International heart journal 64: 1071 (2023) Semantic Scholar
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1.
Pluripotent Stem-Cell Derived Cardiomyocytes
Sadahiro, Taketaro; Ieda, Masaki
(担当:分担執筆, 範囲:Generation of Efficient Mouse and Human Pluripotent Stem Using)
2021年7月 (ISBN: 9781071614846)
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2.
生体の科学
貞廣, 威太郎; 家田, 真樹
(担当:分担執筆, 範囲:心臓幹細胞‐その発生と臨床応用について‐)
医学書院 2021年4月
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3.
循環器専門医
藤田, 諒; 貞廣, 威太郎; 家田, 真樹
(担当:分担執筆, 範囲:Direct reprogrammingによる心筋再生)
一般社団法人 日本循環器学会 2020年11月
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4.
ダイレクトリプログラミング ~再生医療の新展開~
村方, 好子; 貞廣, 威太郎; 家田, 真樹
(担当:分担執筆, 範囲:ダイレクトリプログラミングによる心筋再生)
2020年8月 (ISBN: 9784860436711)
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5.
Precision Medicine
山田優; 貞廣, 威太郎; 家田真樹
(担当:分担執筆, 範囲:ダイレクトリプログラミングによる心臓再生)
北隆館 2020年6月
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6.
医学のあゆみ
安部, 悠人; 貞廣, 威太郎; 家田真樹
(担当:分担執筆, 範囲:非ステロイド性抗炎症薬ジクロフェナクによる心筋ダイレクトリプログラミングの促進)
2020年5月
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7.
実験医学増刊
貞廣, 威太郎; 家田真樹
(担当:分担執筆, 範囲:心筋再生のメカノバイオロジー)
2020年4月 (ISBN: 9784758103862)
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281.
Impact of Change in Left Ventricular Ejection Fraction and Its Prognostic Value in Patients with Heart Failure after MitraClip
南健太郎; 山本昌良; 星, 智也; 佐藤希美; 矢口拓実; 中務智文; 町野智子; 石津智子; 家田真樹
第87回日本循環器学会学術集会
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282.
Prognostic Impact of Impaired Right Ventricular Free Wall Longitudinal Strain in Patients with Severe Aortic Stenosis after Transcatheter Aortic Valve Implantation
Noor, Albakaa; Kimi, Sato; Tomofumi, Nakatsukasa; Naoto, Kawamatsu; Masayoshi, Yamamoto; Tomoko, Machino; Takumi, Yaguchi; Yuichiro, Ishii; Daigo, Hiraya; Hiroaki, Watabe; Hoshi, Tomoya; Tomoko, Ishizu; Yoshihiro, Seo; Masaki, Ieda
第87回日本循環器学会学術集会
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283.
Association between Peri-coronary Adipose Tissue Attenuation on Coronary Computed Tomography Angiography and Coronary High-intensity Plaque on T1-weighted Magnetic Resonance Imaging
Yuichiro, Ishii; Hiroaki, Watabe; Takako, Ichinohe; Daigo, Hiraya; Hoshi, Tomoya; Masaki, Ieda
第87回日本循環器学会学術集会
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284.
Aortic High-Intensity Plaque is Associated with Aortic Raptured Plaque and Perioperative Myocardial Infarction in Chronic Coronary Syndrome Patients
渡部, 浩明; 矢口拓実; 石井雄一郎; 一戸貴子; 平谷, 太吾; 星, 智也; 家田真樹
第87回日本循環器学会学術集会
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285.
Hemodynamic Characteristics and Prosthesis-patient Mismatch after Transcatheter Aortic Valve Implantation with Balloon-expandable Transcather Heart Valve
星, 智也; 矢口拓実; 石井雄一郎; 佐藤希美; 平谷, 太吾; 渡部, 浩明; 家田真樹
第87回日本循環器学会学術集会
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286.
In Vivo Direct Reprogramming Improves Cardiac Function in Heart Failure with Preserved Ejection Fraction
Yamada, Yu; Sadahiro, Taketaro; Abe, Yuto; Nakano, Koji; Honda, Seiichiro; Ieda, Masaki
第87回日本循環器学会学術集会
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287.
当院における急性大動脈解離の検討
中澤, 陽子; 西, 功; 錦井, 牧子; 丸山, 秀和; 鈴木, 祥司; 家田, 真樹
第26回茨城循環器研究会
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288.
直接リプログラミングによる新しい心臓再生法の開発
家田,真樹
AMED/NC課題 患者市民参画イベント患者・社会と考える再生医療~⼼疾患の再⽣医療~
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289.
Durability of the Isolated Area after the Antrum Pulmonary Vein Isolation Using the Radiofrequency Hot-Balloon Catheter
Yamasaki, Hiro; Aonuma, Kazutaka; Shinoda, Yasutoshi; Komatsu, Yuki; Watanabe, Hiroaki; Hattori, Masayuki; Kimata, Akira; Aita, Satoshi; Machino, Takeshi; Igarashi, Miyako; Sekiguchi, Yukio; Nogami, Akihiko; Ieda, Masaki
The 83rd Annual Scientific Meeting of the Japanese Circulation Society
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290.
心エコーによるHFpEF, HFmrEFの評価
Yoshihiro, Seo; Masayoshi, Yamamoto; Tomoko, Ishizu; Masaki, Ieda; Nobuyuki, Ohte
第23回日本心不全学会学術集会 木原 康樹 招待有り
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291.
フレイリティが後期高齢者の心形態に及ぼす影響について
Yoshihiro, Seo; Tomoko, Ishizu; Masaki, Ieda; Nobuyuki, Ohte
第67回日本心臓病学会学術集会
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292.
結果報告:成人先天性心疾患患者における直接型経口抗凝固薬の有用性に関する検討
増田 慶太; 石津, 智子; 家田, 真樹
第22回日本成人先天性心疾患学会総会・学術集会 日本成人先天性心疾患学会
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1. 2023-001890: 心臓拡張機能改善剤および心臓拡張機能改善剤のスクリーニング方法
家田真樹; 山田優; 貞廣, 威太郎 -
2. 2023-004673: キメラ非ヒト哺乳動物を製造する方法、心臓または心臓組織を製造する方法
家田真樹; 安部, 悠人; 貞廣, 威太郎
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