ホーム > 藤山 知之/ Fujiyama, Tomoyuki
藤山 知之
Fujiyama, Tomoyuki
国際統合睡眠医科学研究機構 , 助教 International Institute for Integrative Sleep Medicine , Assistant Professor
オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
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1.
Exocyst complex component 1 (Exoc1) loss in dormant oocyte disrupts c-KIT and growth differentiation factor (GDF9) subcellular localization and causes female infertility in mice.
Chi Lieu Kim Nguyen; Yumeno Kuba; Hoai Thu Le; Hossam Hassan Shawki (+19 著者) Seiya Mizuno
Cell death discovery 11: 17 (2025)
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2.
Partial activation of salt-inducible kinase 3 delays the onset of wakefulness and alleviates hypersomnia due to the lack of protein kinase A-phosphorylation site
Shinya Nakata; Tomoyuki Fujiyama; Fuyuki Asano; Haruna Komiya (+9 著者) Masashi Yanagisawa
SLEEP (2024) Semantic Scholar
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3.
Crucial role of TFAP2B in the nervous system for regulating NREM sleep.
Ayaka Nakai; Mitsuaki Kashiwagi; Tomoyuki Fujiyama; Kanako Iwasaki (+4 著者) Yu Hayashi
Molecular brain 17: 13 (2024) Semantic Scholar
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4.
SIK3-HDAC4 in the suprachiasmatic nucleus regulates the timing of arousal at the dark onset and circadian period in mice.
Fuyuki Asano; Staci J Kim; Tomoyuki Fujiyama; Chika Miyoshi (+11 著者) Masashi Yanagisawa
Proceedings of the National Academy of Sciences of the United States of America 120: e2218209120 (2023) Semantic Scholar
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5.
Kinase signalling in excitatory neurons regulates sleep quantity and depth.
Staci J Kim; Noriko Hotta-Hirashima; Fuyuki Asano; Tomohiro Kitazono (+23 著者) Hiromasa Funato
Nature 612: 512 (2022) Semantic Scholar
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6.
Mice Lacking Cerebellar Cortex and Related Structures Show a Decrease in Slow-Wave Activity With Normal Non-REM Sleep Amount and Sleep Homeostasis
Tomoyuki Fujiyama; Henri Takenaka; Fuyuki Asano; Kazuya Miyanishi (+7 著者) Hiromasa Funato
Frontiers in Behavioral Neuroscience 16: 910461 (2022) Semantic Scholar
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7.
The Role of Reproductive Hormones in Sex Differences in Sleep Homeostasis and Arousal Response in Mice.
Jinhwan Choi; Staci J Kim; Tomoyuki Fujiyama; Chika Miyoshi (+3 著者) Hiromasa Funato
Frontiers in neuroscience 15: 739236 (2021) Semantic Scholar
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8.
Efficient induction of proximity-dependent labeling by biotin feeding in BMAL1-BioID knock-in mice.
Kazuya Murata; Asuka Mimura; Hayate Suzuki; Natsuki Mikami (+10 著者) Fumihiro Sugiyama
Journal of biochemistry (2021) Semantic Scholar
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9.
Induction of Mutant Sik3Sleepy Allele in Neurons in Late Infancy Increases Sleep Need.
Kanako Iwasaki; Tomoyuki Fujiyama; Shinya Nakata; Minjeong Park (+10 著者) Masashi Yanagisawa
The Journal of neuroscience : the official journal of the Society for Neuroscience 41: 2733 (2021) Semantic Scholar
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10.
An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension.
Gusty R T Ryanto; Koji Ikeda; Kazuya Miyagawa; Ly Tu (+5 著者) Noriaki Emoto
Nature communications 12: 1720 (2021) Semantic Scholar
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11.
Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β.
Ayaka Nakai; Tomoyuki Fujiyama; Nanae Nagata; Mitsuaki Kashiwagi (+13 著者) Yu Hayashi
Genetics 216: 753 (2020) Semantic Scholar
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12.
Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.
Minjeong Park; Chika Miyoshi; Tomoyuki Fujiyama; Miyo Kakizaki (+7 著者) Hiromasa Funato
Scientific reports 10: 8676 (2020) Semantic Scholar
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13.
Ptf1a inactivation in adult pancreatic acinar cells causes apoptosis through activation of the endoplasmic reticulum stress pathway.
Morito Sakikubo; Kenichiro Furuyama; Masashi Horiguchi; Shinichi Hosokawa (+9 著者) Yoshiya Kawaguchi
Scientific reports 8: 15812 (2018) Semantic Scholar
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14.
A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice.
Honda T; Fujiyama T; Miyoshi C; Ikkyu A (+6 著者) Yanagisawa M
Proceedings of the National Academy of Sciences of the United States of America 115: 10458 (2018) Semantic Scholar
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15.
Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain
Tomoyuki Fujiyama; Satoshi Miyashita; Yousuke Tsuneoka; Kazumasa Kanemaru (+14 著者) Mikio Hoshino
Cell Reports 24: 79 (2018) Semantic Scholar
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16.
Quantitative phosphoproteomic analysis of the molecular substrates of sleep need
Zhiqiang Wang; Jing Ma; Chika Miyoshi; Yuxin Li (+20 著者) Qinghua Liu
Nature 558: 435 (2018) Semantic Scholar
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17.
Forward-genetics analysis of sleep in randomly mutagenized mice
Hiromasa Funato; Chika Miyoshi; Tomoyuki Fujiyama; Takeshi Kanda (+33 著者) Masashi Yanagisawa
NATURE 539: 378 (2016) Semantic Scholar
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18.
Identification of mutations through dominant screening for obesity using C57BL/6 substrains
Mohammad Sarowar Hossain; Fuyuki Asano; Tomoyuki Fujiyama; Chika Miyoshi (+16 著者) Masashi Yanagisawa
SCIENTIFIC REPORTS 6: 32453 (2016) Semantic Scholar
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19.
The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO₂.
Ruffault PL; D'Autréaux F; Hayes JA; Nomaksteinsky M (+7 著者) Goridis C
eLife 2015: (2015)
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20.
Unipotent, Atoh1(+) progenitors maintain the Merkel cell population in embryonic and adult mice
Margaret C. Wright; Erin G. Reed-Geaghan; Alexa M. Bolock; Tomoyuki Fujiyama (+1 著者) Stephen M. Maricich
JOURNAL OF CELL BIOLOGY 208: 367 (2015) Semantic Scholar
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1.
「眠気」の生化学的な実体に迫るー睡眠要求を規定するリン酸化タンパク質群の同定
藤山知之, 柳沢正史
(担当:共著)
実験医学 2019年1月号 Vol.37 No.1 「なぜ、いま核酸医薬なのか」
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1.
レム睡眠制御における非選択的陽イオンチャネルNALCNの遺伝学的機能解析の現状と展望
藤山知之; 船戸弘正; 柳沢正史
日本睡眠学会第48回定期学術集会シンポジウム 34 「ムーンショット:睡眠基礎研究の最前線」 2024年7月 招待有り
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2.
終脳および橋延髄のNALCNはレム睡眠制御において異なる役割を持つ
Tomoyuki Fujiyama; Hiromasa Funato; Masashi Yanagisawa
第73回日本薬理学会北部会 次世代薬理学セミナー 次世代神経薬理学の最前線 2022年9月 招待有り
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3.
脳の性別を決定する新たなメカニズム — Ptf1a遺伝子が脳の男性化・女性化に働く
藤山知之
第29回日本行動内分泌研究会 2018年9月5日 招待有り
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4.
Forebrain Ptf1a is required for sexual differentiation of the brain
藤山知之
2018日韓神経発生学共同シンポジウム 2018年6月8日 招待有り
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5.
Forebrain Ptf1a is required for sexual differentiation of the brain
藤山知之
22nd Biennial Meeting of the International Society of Developmental Neuroscience 2018年5月22日
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6.
Hypothalamic Ptf1a is required for sexual differentiation of the brain and behavior
藤山知之
2017 SfN Annual Meeting 2017年11月11日
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7.
連鎖解析と全エクソームシーケンスによるDreamless 変異家系特異的な一塩基置換の 同定とCRISPR/Casによる再現
藤山知之
第121回日本解剖学会総会・全国学術集会 2016年3月28日 招待有り
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8.
発生期視床下部に発現する遺伝子と脳の性分化
藤山 知之
名古屋大学高等研究院・若手新分野創成ワークショップ「脳を知り、疾患を理解する」 招待有り
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