ホーム > 鵜木 隆光/ Unoki, Takamitsu

鵜木 隆光

ALUMNI 2025年6月現在、筑波大学が主たる所属機関ではありません

Unoki, Takamitsu

昭和薬科大学 , 衛生化学研究室 , 講師
Showa Pharmaceutical University

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  1. 1. Multi-defense pathways against electrophiles through adduct formation by low molecular weight substances with sulfur atoms Yoshito Kumagai; Yumi Abiko; Masahiro Akiyama; Takamitsu UnokiYasuhiro Shinkai
      Toxicological Sciences (2024) Semantic Scholar
  2. 2. BDNF specifically expressed in hippocampal neurons is involved in methylmercury neurotoxicity resistance Masatake Fujimura; Takamitsu Unoki
      Environmental Toxicology 39: 3149 (2024) Semantic Scholar
  3. 3. Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress Masahiro Akiyama; Takamitsu Unoki; Hanako Aoki; Akiyuki Nishimura (+7 著者) Yoshito Kumagai
      Redox Biology 57: 102514 (2022) Semantic Scholar
  4. 4. Preliminary evaluation of the mechanism underlying vulnerability/resistance to methylmercury toxicity by comparative gene expression profiling of rat primary cultured cerebrocortical and hippocampal neurons Masatake Fujimura; Takamitsu Unoki
      The Journal of Toxicological Sciences 47: 211 (2022) Semantic Scholar
  5. 5. Concentrations of nucleophilic sulfur species in small Indian mongoose (Herpestes auropunctatus) in Okinawa, Japan Sawako Horai; Yumi Abiko; Takamitsu Unoki; Yasuhiro Shinkai (+3 著者) Yoshito Kumagai
      Chemosphere 295: 133833 (2022) Semantic Scholar
  6. 6. Spatio-temporal distribution of reactive sulfur species during methylmercury exposure in the rat brain. Takamitsu Unoki; Masahiro Akiyama; Yasuhiro Shinkai; Yoshito KumagaiMasatake Fujimura
      The Journal of toxicological sciences 47: 31 (2022) Semantic Scholar
  7. 7. Decreased plasma thiol antioxidant capacity precedes neurological signs in a rat methylmercury intoxication model Masatake Fujimura; Fusako Usuki; Takamitsu Unoki
      Food and Chemical Toxicology 146: 111810 (2020) Semantic Scholar
  8. 8. Repression of mercury accumulation and adverse effects of methylmercury exposure is mediated by cystathionine γ-lyase to produce reactive sulfur species in mouse brain Masahiro Akiyama; Takamitsu Unoki; Eiko Yoshida; Yunjie Ding (+3 著者) Yoshito Kumagai
      Toxicology Letters 330: 128 (2020) Semantic Scholar
  9. 9. Erratum: Environmental electrophile-mediated toxicity in mice lacking nrf2, CSE, or both (Environ Health Perspect, (2019) 127, 6, 10.1289/EHP4949) Masahiro Akiyama; Takamitsu Unoki; Yasuhiro Shinkai; Isao Ishii (+3 著者) Yoshito Kumagai
      Environmental Health Perspectives 128: 1 (2020) Semantic Scholar
  10. 10. Nrf2 Activation and Its Coordination with the Protective Defense Systems in Response to Electrophilic Stress. Unoki T; Akiyama M; Kumagai Y
      International journal of molecular sciences 21: (2020) Semantic Scholar
  11. 11. Combined exposure to environmental electrophiles enhances cytotoxicity and consumption of persulfide Masahiro Akiyama; Takamitsu Unoki; Yoshito Kumagai
      Fundamental Toxicological Sciences 7: 161 (2020) Semantic Scholar
  12. 12. Adaptive Responses to Electrophilic Stress and Reactive Sulfur Species as their Regulator Molecules. Kumagai Y; Akiyama M; Unoki T
      Toxicological research 35: 303 (2019) Semantic Scholar
  13. 13. Environmental electrophile-mediated toxicity in mice lacking Nrf2, CSE, or both Masahiro Akiyama; Takamitsu Unoki; Yasuhiro Shinkai; Isao Ishii (+3 著者) Yoshito Kumagai
      Environmental Health Perspectives 127: 67002 (2019) Semantic Scholar
  14. 14. Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation. Unoki T; Akiyama M; Kumagai Y; Gonçalves FM (+2 著者) Aschner M
      Frontiers in genetics 9: 373 (2018) Semantic Scholar
  15. 15. The Capture of Cadmium by Reactive Polysulfides Attenuates Cadmium-Induced Adaptive Responses and Hepatotoxicity Masahiro Akiyama; Yasuhiro Shinkai; Takamitsu Unoki; Ilseob Shim (+1 著者) Yoshito Kumagai
      Chemical Research in Toxicology 30: 2209 (2017) Semantic Scholar
  16. 16. The Capture of Cadmium by Reactive Polysulfides Attenuates Cadmium-Induced Adaptive Responses and Hepatotoxicity Masahiro Akiyama; Yasuhiro Shinkai; Takamitsu Unoki; Ilseob Shim (+1 著者) Yoshito Kumagai
      CHEMICAL RESEARCH IN TOXICOLOGY 30: 2209 (2017) Semantic Scholar
  17. 17. Polysulfide Na2S4 regulates the activation of PTEN/Akt/CREB signaling and cytotoxicity mediated by 1,4-naphthoquinone through formation of sulfur adducts Yumi Abiko; Yasuhiro Shinkai; Takamitsu Unoki; Reiko Hirose (+1 著者) Yoshito Kumagai
      SCIENTIFIC REPORTS 7: 4814 (2017) Semantic Scholar
  18. 18. 1,4-Naphthoquinone activates the HSP90/HSF1 pathway through the S-arylation of HSP90 in A431 cells: Negative regulation of the redox signal transduction pathway by persulfides/polysulfides. Yumi Abiko; Liang Sha; Yasuhiro Shinkai; Takamitsu Unoki (+5 著者) Yoshito Kumagai
      Free radical biology & medicine 104: 118 (2017) Semantic Scholar
  19. 19. 1,4-Naphthoquinone-mediated activation of the HSP90/HSF1 signal transduction pathway and its negative regulation by reactive sulfur species in human A431 cells T. Unoki; Y. Shinkai; L. Sha; R. HiroseY. Kumagai
      TOXICOLOGY LETTERS 259: S175 (2016) Semantic Scholar
  20. 20. An atmospheric electrophile activates heat shock factor 1 through S-arylation of heat shock protein 90 R. Hirose; T. Unoki; Y. Abiko; Y. Shinkai (+1 著者) Y. Kumagai
      TOXICOLOGY LETTERS 258: S253 (2016) Semantic Scholar
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