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望月 貴年

MOCHIZUKI, Takatoshi

国際統合睡眠医科学研究機構 , 教授
International Institute for Integrative Sleep Medicine

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  1. 1. Pharmacological inhibition of histamine N-methyltransferase extends wakefulness and suppresses cataplexy in a mouse model of narcolepsy Fumito Naganuma; Birkan Girgin; Anne Bernadette S Agu; Kyosuke Hirano (+5 著者) Takeo Yoshikawa
      SLEEP (2024) Semantic Scholar
  2. 2. Sleep disturbance after cessation of cannabis administration in mice Asano, T.; Takemoto, H.; Horita, T.; Tokutake, T. (+2 著者) Nitta, A.
      Neuropsychopharmacology Reports (2023) Semantic Scholar
  3. 3. Action potential firing rhythms in the suprachiasmatic nucleus of the diurnal grass rat, Arvicanthis niloticus. Eri Morioka; Tsubasa Miyamoto; Sakura Tamogami; Takahiro Koketsu (+3 著者) Masayuki Ikeda
      Neuroscience letters 792: 136954 (2023) Semantic Scholar
  4. 4. Orexin neurons inhibit sleep to promote arousal De Luca, R.; Nardone, S.; Grace, K.P.; Venner, A. (+13 著者) Arrigoni, E.
      Nature Communications 13: 4163 (2022) Semantic Scholar
  5. 5. Histamine as an Alert Signal in the Brain Mochizuki, T.
      Current Topics in Behavioral Neurosciences 59: (2022) Semantic Scholar
  6. 6. Intracellular interplay between cholecystokinin and leptin signalling for satiety control in rats Koizumi, H.; Mohammad, S.; Ozaki, T.; Muto, K. (+5 著者) Ikeda, M.
      Scientific Reports 10: 12000 (2020) Semantic Scholar
  7. 7. Dual orexin receptor antagonists increase sleep and cataplexy in wild type mice Mahoney, C.E.; Mochizuki, T.; Scammell, T.E.
      Sleep 43: zsz302 (2020) Semantic Scholar
  8. 8. Reassessing the role of histaminergic tuberomammillary neurons in arousal control Venner, A.; Mochizuki, T.; Luca, R.D.; Anaclet, C. (+3 著者) Fuller, P.M.
      Journal of Neuroscience 39: 8929 (2019) Semantic Scholar
  9. 9. Histamine N-methyltransferase regulates aggression and the sleep-wake cycle Fumito Naganuma; Tadaho Nakamura; Takeo Yoshikawa; Tomomitsu Iida (+7 著者) Kazuhiko Yanai
      SCIENTIFIC REPORTS 7: 15899 (2017) Semantic Scholar
  10. 10. Descending projections from the basal forebrain to the orexin neurons in mice Lindsay J. Agostinelli; Loris L. Ferrari; Carrie E. Mahoney; Takatoshi Mochizuki (+2 著者) Thomas E. Scammell
      JOURNAL OF COMPARATIVE NEUROLOGY 525: 1668 (2017) Semantic Scholar
  11. 11. Histamine N-methyltransferaseの欠損はマウスにおいて攻撃性を高め、睡眠サイクルの異常を引き起こす 長沼 史登; 吉川 雄朗; 堀米 愛; 三浦 大和 (+3 著者) 谷内 一彦
      日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集 37回・45回: 163 (2015)
  12. 12. Input and output systems of orexin neurons Mochizuki, T.; Yoshida-Court, K.
      Orexin and Sleep: Molecular, Functional and Clinical Aspects (2015) Semantic Scholar
  13. 13. Acute enhancement of non-rapid eye movement sleep in rats after drinking water contaminated with cadmium chloride Katsuya Unno; Kurumi Yamoto; Kouhei Takeuchi; Aya Kataoka (+4 著者) Masayuki Ikeda
      JOURNAL OF APPLIED TOXICOLOGY 34: 205 (2014) Semantic Scholar
  14. 14. Orexin Gene Therapy Restores the Timing and Maintenance of Wakefulness in Narcoleptic Mice Sandor Kantor; Takatoshi Mochizuki; Stefan N. Lops; Brian Ko (+3 著者) Thomas E. Scammell
      SLEEP 36: 1129 (2013) Semantic Scholar
  15. 15. Amygdala Lesions Reduce Cataplexy in Orexin Knock-Out Mice Christian R. Burgess; Yo Oishi; Takatoshi Mochizuki; John H. PeeverThomas E. Scammell
      JOURNAL OF NEUROSCIENCE 33: 9734 (2013) Semantic Scholar
  16. 16. Role of the medial prefrontal cortex in cataplexy Oishi, Y.; Williams, R.H.; Agostinelli, L.; Arrigoni, E. (+3 著者) Scammell, T.E.
      Journal of Neuroscience 33: 9743 (2013) Semantic Scholar
  17. 17. Hcrtr1 and 2 signaling differentially regulates depression-like behaviors Michael M. Scott; Jacob N. Marcus; Ami Pettersen; Shari G. Birnbaum (+4 著者) Michael Lutter
      BEHAVIOURAL BRAIN RESEARCH 222: 289 (2011) Semantic Scholar
  18. 18. Orexin receptor 2 expression in the posterior hypothalamus rescues sleepiness in narcoleptic mice Takatoshi Mochizuki; Elda Arrigoni; Jacob N. Marcus; Erika L. Clark (+5 著者) Thomas E. Scammell
      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108: 4471 (2011) Semantic Scholar
  19. 19. Activation of the basal forebrain by the orexin/hypocretin neurones E. Arrigoni; T. Mochizuki; T. E. Scammell
      ACTA PHYSIOLOGICA 198: 223 (2010) Semantic Scholar
  20. 20. Abnormal Sleep/Wake Dynamics in Orexin Knockout Mice Cecilia G. Diniz Behn; Elizabeth B. Klerman; Takatoshi Mochizuki; Shih-Chieh LinThomas E. Scammell
      SLEEP 33: 297 (2010) Semantic Scholar
1 2 3 4
  1. 1. Hypothalamic flip-flop仮説 望月貴年
    ライフ・サイエンス社: 睡眠医療 Vol 16(2) 2022年6月
  2. 2. Histamine as an alert signal in the brain Takatoshi Mochizuki (担当:分担執筆)
    Springer Nature Switzerland AG: Current topics in behavioral neurosciences 2021年8月
  3. 3. 時計遺伝子と睡眠覚醒 望月貴年; 池田真行 (担当:分担執筆)
    ライフ・サイエンス社: 睡眠医療 Vol 14(1) 2020年3月
  4. 4. Input and output systems of orexin neurons Takatoshi Mochizuki; Kyoko Yoshida-Court (担当:分担執筆)
    Springer International Publishing AG: Orexins and Sleep: molecular, functional, and clinical aspects. 2015年
  5. 5. 睡眠と時計遺伝子 望月貴年; 裏出良博 (担当:分担執筆)
    中外医学社: Annual Review 神経 1999年
  1. 1. Orexin receptor antagonists and behavioral changes in mice 望月 貴年
    2019 Oriental International Sleep Medicine Summit Forum (Shanghai) 2019年10月18日 招待有り
  2. 2. Roles of histamine neurons in narcolepsy 望月 貴年
    第19回日本ヒスタミン学会（仙台） 2015年11月 招待有り
  3. 3. Histamine N-methyltransferaseの欠損はマウスにおいて攻撃性を高め、睡眠サイクルの異常を引き起こす 長沼 史登; 吉川 雄朗; 堀米 愛; 三浦 大和; 中村 正帆; 矢内 敦; 望月 貴年; 谷内 一彦
    日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集 2015年9月 日本生物学的精神医学会・日本神経精神薬理学会
  4. 4. 視床下部ヒスタミンニューロンに共存するGABAの役割について 望月 貴年
    第38回日本睡眠学会（秋田） 2013年6月 招待有り
  5. 5. Orexin and histamine as arousal signals in the brain 望月 貴年
    The 8th International Symposium on Respiratory Disease & ATS (Shanghai) 2012年11月 招待有り
  6. 6. オレキシン神経の出力系としてのヒスタミン神経を再考する 望月 貴年
    第37回日本睡眠学会（横浜） 2012年6月 招待有り
  7. 7. Unraveling the pathways that cause sleepiness in narcoleptic mice 望月 貴年
    Associated Professional Sleep Societies 24th Annual Meeting (San Antonio) 2010年6月 招待有り
  8. 8. Rescue of narcolepsy phenotypes in orexin receptor disrupted mice – an application of Cre-loxP system 望月 貴年
    Associated Professional Sleep Societies 22nd Annual Meeting (Baltimore) 2008年6月 招待有り
  9. 9. Elevated body temperature during sleep in orexin knockout mice 望月 貴年
    Associated Professional Sleep Societies 20th Annual Meeting (Salt Lake City) 2006年6月 招待有り
  10. 10. Sleep-wake regulation in mice devoid of histamine H1 receptors 望月 貴年
    International Histamine Symposium (Sendai) 2000年11月

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