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山下年晴

Yamashita, Toshiharu

医学医療系 , 助教
Institute of Medicine , Assistant Professor

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21. Glucocorticoid Impaired the Wound Healing Ability of Endothelial Progenitor Cells by Reducing the Expression of CXCR4 in the PGE2 Pathway Carolina, Erica; Kato, Toshiki; Vuong Cat, Khanh; Moriguchi, Kana (+3 著者) Ohneda, Osamu
Frontiers in Medicine 5: (2018) Semantic Scholar
22. Deterioration of alveolar development in mice with both HIF-3α knockout and HIF-2α knockdown Amin, Firman Zulkifli; Yamashita, Toshiharu; Ohneda, Osamu
BMC research notes 11: 449 (2018) Semantic Scholar
23. Aging impairs beige adipocyte differentiation of mesenchymal stem cells via the reduced expression of Sirtuin 1 Vuong Cat Khanh; Amin Firman Zulkifli; Chiho Tokunaga; Toshiharu Yamashita (+1 著者) Osamu Ohneda
Biochemical and Biophysical Research Communications 500: 682 (2018) Semantic Scholar
24. Elevated Expression of Dkk-1 by Glucocorticoid Treatment Impairs Bone Regenerative Capacity of Adipose Tissue-Derived Mesenchymal Stem Cells. Toshiki Kato; Vuong Cat Khanh; Kazutoshi Sato; Kenichi Kimura (+4 著者) Osamu Ohneda
Stem cells and development 27: 85 (2018) Semantic Scholar
25. SDF-1 improves wound healing ability of glucocorticoid-treated adipose tissue-derived mesenchymal stem cells Toshiki Kato; Vuong Cat Khanh; Kazutoshi Sato; Kosuke Takeuchi (+5 著者) Osamu Ohneda
Biochemical and Biophysical Research Communications 493: 1010 (2017) Semantic Scholar
26. SDF-1 improves wound healing ability of glucocorticoid-treated adipose tissue-derived mesenchymal stem cells Kato, Toshiki; Khanh, Vuong Ca; Sato, Kazutoshi; Takeuchi, Kosuke (+5 著者) Ohneda, Osamu
Biochemical and biophysical research communications 493: 1010 (2017) Semantic Scholar
27. Uremic Toxins Affect the Imbalance of Redox State and Overexpression of Prolyl Hydroxylase 2 in Human Adipose Tissue-Derived Mesenchymal Stem Cells Involved in Wound Healing Vuong Cat Khanh; Kinuko Ohneda; Toshiki Kato; Toshiharu Yamashita (+2 著者) Osamu Ohneda
Stem Cells and Development 26: 948 (2017) Semantic Scholar
28. Uremic Toxins Affect the Imbalance of Redox State and Overexpression of Prolyl Hydroxylase 2 in Human Adipose Tissue-Derived Mesenchymal Stem Cells Involved in Wound Healing Khanh, Vuong Ca; Ohneda, Kinuko; Kato, Toshiki; Yamashita, Toshiharu (+2 著者) Ohneda, Osamu
Stem cells and development 26: 948 (2017) Semantic Scholar
29. Hypoxia promotes the phenotypic change of aldehyde dehydrogenase activity of breast cancer stem cells Akira Shiraishi; Kana Tachi; Nesrine Essid; Ikki Tsuboi (+5 著者) Osamu Ohneda
CANCER SCIENCE 108: 362 (2017) Semantic Scholar
30. The ectopic FOXA1 expression correlates to the luminal breast cancer stem cells K. Tachi; A. Shiraishi; H. Bando; T. Yamashita (+7 著者) O. Ohneda
CANCER RESEARCH 77: 281 (2017) Semantic Scholar
31. In vivo retinal and choroidal hypoxia imaging using a novel activatable hypoxia-selective near-infrared fluorescent probe Shinichi Fukuda; Kensuke Okuda; Genichiro Kishino; Sujin Hoshi (+7 著者) Tetsuro Oshika
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 254: 2373 (2016) Semantic Scholar
32. Microvesicles derived from Alde-Low EPCs support the wound healing capacity of AT-MSCs Tran Cam Tu; Toshiharu Yamashita; Toshiki Kato; Masumi Nagano (+5 著者) Osamu Ohneda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 477: 68 (2016) Semantic Scholar
33. Microvesicles derived from Alde-Low EPCs support the wound healing capacity of AT-MSCs Tran, Cam Tu; Yamashita, Toshiharu; Kato, Toshiki; Nagano, Masumi (+5 著者) Ohneda, Osamu
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 477: 68 (2016) Semantic Scholar
34. Microvesicles derived from Alde-Low EPCs support the wound healing capacity of AT-MSCs Tran Cam Tu; Toshiharu Yamashita; Toshiki Kato; Masumi Nagano (+5 著者) Osamu Ohneda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 477: 68 - 75 (2016) Semantic Scholar
35. Microvesicles enhance the mobility of human diabetic adipose tissue-derived mesenchymal stem cells in vitro and improve wound healing in vivo Nhu Thuy Trinh; Toshiharu Yamashita; Tran Cam Tu; Toshiki Kato (+2 著者) Osamu Ohneda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 473: 1111 (2016) Semantic Scholar
36. Increased Expression of EGR-1 in Diabetic Human Adipose Tissue-Derived Mesenchymal Stem Cells Reduces Their Wound Healing Capacity Nhu-Thuy Trinh; Toshiharu Yamashita; Kinuko Ohneda; Kenichi Kimura (+2 著者) Osamu Ohneda
STEM CELLS AND DEVELOPMENT 25: 760 (2016) Semantic Scholar
37. FOXA1 expression affects to the proliferation activity of luminal breast cancer stem cell populations Yamashita,Toshiharu; Kana,Tachi; Akira,Shiraishi; Hiroko,Bando (+4 著者) Osamu,Ohneda
Cancer science 107: 281 (2016) Semantic Scholar
38. FOXA1 expression affects the proliferation activity of luminal breast cancer stem cell populations Kana Tachi; Akira Shiraishi; Hiroko Bando; Toshiharu Yamashita (+3 著者) Osamu Ohneda
Cancer Science 107: 281 (2016) Semantic Scholar
39. A chemokine receptor, CXCR4, which is regulated by hypoxia inducible factor 2α, is crucial for functional EPC migration to ischemic tissue and wound repair Tran,Cam Tu; Masumi,Nagano; Toshiharu,Yamashita; Hamada,Hiromi (+2 著者) Osamu,Ohneda
STEM CELLS AND DEVELOPMENT 25: 266 (2016) Semantic Scholar
40. Impaired Expression of HIF-2 alpha Induces Compensatory Expression of HIF-1 alpha for the Recovery From Anemia Ikki Tsuboi; Toshiharu Yamashita; Masumi Nagano; Kenichi Kimura (+1 著者) Osamu Ohneda
JOURNAL OF CELLULAR PHYSIOLOGY 230: 1534 (2015) Semantic Scholar

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1. HIFのin vivoモデルによる機能解析山下年晴; 大根田修 (担当:監修)
実験医学羊土社 2007年9月
2. 環境応答系転写因子の分子機構の解明山下年晴; 山本, 雅之 (担当:監修)
化学工業 2003年1月

1. Extracellular vesicles derived from Wharton’s Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway Yun-Hsuan, Chang; Vuong; Cat Khanh; Toshiharu, Yamashita; Osamu, Ohneda
Tsukuba Global Science Week 2022 2022年9月30日
2. Nicotine and SARS-CoV-2 Protein Induce the Malignancy of Lung Cancer Cell. International Student Presentations of Medical and Life Sciences Session. Lomanto; Markus Yovian Widjaja; Nguyen; Hoai-Nga Thi; Khanh, Vuong Ca; Yamashita, Toshiharu; Ohneda, Osamu
Tsukuba Global Science Week 2022 2022年9月29日
3. SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells Nguyen; Hoai-Nga Thi; Khanh, Vuong Ca; Yamashita, Toshiharu; Ohneda, Osamu
Tsukuba Global Science Week 2022 2022年9月29日
4. Transformed Extracellular Vesicles with High Angiogenic Ability as Therapeutics of Distal Ischemic Tissues Ngo, Nhat-Hoang; Khanh, Vuong Ca; Yamashita, Toshiharu; Ohneda, Osamu
Tsukuba Global Science Week 2022 2022年9月29日
5. Quantification of ex-vivo tissue activity by polarization dynamics imaging using Jones matrix optical coherence tomography Mukherjee, Pradipta; Miyazawa, Arata; Shen, Larina; Fukuda, Shinichi; Yamashita, Toshiharu; Oka, Yuki; Abd El-Sadek, Ibrahim; Makita, Shuichi; Matsusaka, Satoshi; Oshika, Tetsuro; Kano, Hideaki; Yasuno, Yoshiaki
Biomedical Imaging and Sensing Conference 2020 2020年8月24日
6. Effect of soy protein intake on weak bones by the food restriction in young female rats Y, Aikawa; T, Narukawa; K, Kioka; T, Yamashita; N, Sasai; M, Ohtsuki; 麻見, 直美
Human High Performance International Forum 2020 2020年2月17日 ARIHHPセンター
7. Quantification of ex vivo tissue activity by short and long timecourse analysis of multifunctional OCT signals El-Sadek; Ibrahim Abd; Miyazawa, Arata; Shen, Larina; Fukuda, Shinichi; Yamashita,Toshiharu; Oka, Yuki; Mukherjee, Pradipta; Makita, Shuichi; Matsusaka, Satoshi; Oshika, Tetsuro; Kano, Hideaki; Yasuno, Yoshiaki
SPIE Photonics West/ BiOS 2020 2020年2月1日
8. Impairment of Sirt1 plays the key role in the dysfunction of mesenchymal stem cells in beige adipogenesis Vuong Cat, Khanh; Yamashita, Toshiharu; Ohneda, Osamu
The Joint Young Research Meeting in Biomedical Science 2020年1月10日
9. Study the effects of type 2 diabetes mellitus on functions of Wharton jelly's Mesenchymal stem cells for the treatment of diabetic foot ulcer Sipayung; Shinta Masyta; Khanh, Vuong Ca; Yamashita, Toshiharu; Ohneda, Osamu
The Joint Young Research Meeting in Biomedical Science 2020年1月10日
10. Birefringence dynamics imaging for ex-vivo tissue activity quantification using polarization-sensitive optical coherence tomography Mukherjee, Pradipta; El-Sadek; Ibrahim Abd; Miyazawa, Arata; Makita, Shuichi; Shen, Larina; Fukuda, Shinichi; Yamashita, Toshiharu; Oka, Yuki; Matsusaka, Satoshi; Oshika, Tetsuro; Kano, Hideaki; Yasuno, Yoshiaki
Optics Photonics Japan 2019 （日本光学会年次講演会） 2019年12月2日
11. Short and long time-course ex vivo tissues activity quantification by multifunctional OCT El-Sadek; Ibrahim Abd; Miyazawa, Arata; Shen, Larina; Fukuda, Shinichi; Yamashita,Toshiharu; Oka, Yuki; Mukherjee, Pradipta; Makita, Shuichi; Matsusaka, Satoshi; Oshika, Tetsuro; Kano, Hideaki; Yasuno, Yoshiaki
Optics Photonics Japan 2019 （日本光学会年次講演会） 2019年12月2日
12. 老化による脂肪組織由来間葉系幹細胞の創傷治癒能に対する影響の解析原彩美; Vuong, Cat Khanh; Toshiharu, Yamashita; Osamu, Ohneda
第18回日本再生医療学会総会 2019年3月21日
13. より高い治療効果を持つ機能性血管内皮前駆細胞 (EPC) の作成佐藤悠樹; Vuong, Cat Khanh; Toshiharu, Yamashita; Osamu, Ohneda
第18回日本再生医療学会総会 2019年3月21日
14. Effects of aging on mesenchymal stem cells VUONG CAT; KHANH; Yamashita, Toshiharu; Ohneda, Osamu
The 1st University of Tsukuba-University of Science Vietnam Joint Symposium 2019 2019年2月23日
15. Study the effects of Type 2 diabetes mellitus on beige adipogenesis of Mesenchymal stem cells Takeuchi, Kosuke; Khanh, Vuong Ca; Yamashita, Toshiharu; Ohneda, Osamu
Tsukuba Science Week 2018 2018年9月20日
16. The ectopic FOXA1 expression correlates to the luminal breast cancer stem cells Tachi,K; Shiraishi,A; Bando,Hiroko; Yamashita,T; Tsuboi,I; Kato,T; Ichioka,E; Tsushima,Y; Ikeda,T; Iguchi,A; Hara,H; Ohneda,O
39Th San Antonio Breast Cancer Symposium 2016年12月6日
17. The ectopic FOXA1 expression correlates to the luminal breast cancer stem cells Tachi, K; Shiraishi, A; Bando, H; Yamashita, T; Tsuboi, I; Kato, T; Ichioka, E; Tsushima, Y; Ikeda, T; Iguchi, A; Hara, H; Ohneda, O
San Antonio Breast Cancer Symposium 2016年12月6日
18. 筑波大学における臨地実習前OSCEの開発に向けた取組會田, 雄一; 山内, 一由; 上妻, 行則; 渋谷, 和子; 上杉, 憲子; 中川, 嘉; 吉田, 文代; 山下, 年晴; 小池, 朗; 二宮, 治彦
第11回日本臨床検査学教育学会学術大会 2016年8月31日
19. Dual Functions of Hypoxia Inducible Factor-1 alpha for the Commitment of Mouse Embryonic Stem Cells Toward a Neural Lineage Takasaki,Mami; Zhao,Yang; Tsuboi,Ikki; Yamashita,Toshiharu; Ohneda,Osamu
第47回日本発生生物学会 2014年5月28日
20. Deficient expression of HIF-2a in spleen results in compensatory angiogenesis by up-regulated of HIF-1a IkkiTsuboi; 山下,年晴; Satomi,Kobayashi; Osamu,Ohneda
第36回日本分子生物学会 2013年12月3日