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山下年晴

Yamashita, Toshiharu

医学医療系 , 助教
Institute of Medicine , Assistant Professor

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41. The Role of CCL5 in the Ability of Adipose Tissue-Derived Mesenchymal Stem Cells to Support Repair of Ischemic Regions Kenichi Kimura; Masumi Nagano; Georgina Salazar; Toshiharu Yamashita (+5 著者) Osamu Ohneda
STEM CELLS AND DEVELOPMENT 23: 488 (2014)
42. Deficiency of NOX1/Nicotinamide Adenine Dinucleotide Phosphate, Reduced Form Oxidase Leads to Pulmonary Vascular Remodeling Kazumi Iwata; Kanako Ikami; Kuniharu Matsuno; Toshiharu Yamashita (+11 著者) Chihiro Yabe-Nishimura
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 34: 110 (2014) Semantic Scholar
43. Functional endothelial progenitor cells selectively recruit neurovascular protective monocyte-derived F4/80(+)/Ly6c(+) macrophages in a mouse model of retinal degeneration Shinichi Fukuda; Masumi Nagano; Toshiharu Yamashita; Kenichi Kimura (+6 著者) Osamu Ohneda
STEM CELLS 31: 2149 (2013) Semantic Scholar
44. Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation. Keiko Akimoto; Kenichi Kimura; Masumi Nagano; Shingo Takano (+2 著者) Osamu Ohneda
Stem cells and development 22: 1370 (2013) Semantic Scholar
45. A subpopulation of endothelial progenitor cells with low aldehyde dehydrogenase activity attenuates acute ischemic brain injury in rats Kazuhiro Nakamura; Hideo Tsurushima; Aiki Marushima; Masumi Nagano (+3 著者) Akira Matsumura
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 418: 87 (2012) Semantic Scholar
46. Identification of Human Placenta-Derived Mesenchymal Stem Cells Involved in Re-Endothelialization Tu Cam Tran; Kenichi Kimura; Masumi Nagano; Toshiharu Yamashita (+7 著者) Osamu Ohneda
JOURNAL OF CELLULAR PHYSIOLOGY 226: 224 (2011) Semantic Scholar
47. HEMATOPOIESIS - CYTOKINES, SIGNAL TRANSDUCTION, APOPTOSIS AND CELL CYCLE REGULATION POSTER I Pan, Xiaoqing; Suzuki, Norio; Hirano, Ikuo; Yamazaki, Shun (+3 著者) Yamamoto, Masayuki
BLOOD 116: 656 (2010)
48. Isolation and Characterization of Renal Erythropoietin-Producing Cells: Contribution of HIF3 alpha In Vivo Xiaoqing Pan; Norio Suzuki; Ikuo Hirano; Shun Yamazaki (+3 著者) Masayuki Yamamoto
BLOOD 116: 656 (2010)
49. Hypoxia Responsive Mesenchymal Stem Cells Derived from Human Umbilical Cord Blood Are Effective for Bone Repair Masumi Nagano; Kenichi Kimura; Toshiharu Yamashita; Kinuko Ohneda (+4 著者) Osamu Ohneda
STEM CELLS AND DEVELOPMENT 19: 1195 (2010) Semantic Scholar
50. Molecular therapeutic targets for glioma angiogenesis Shingo Takano; Toshiharu Yamashita; Osamu Ohneda
Journal of Oncology 2010: 351908 (2010) Semantic Scholar
51. SDF-1とCXCR7はグリオーマの血管新生と浸潤の重要な標的分子である高野,晋吾; 山下,年晴; 長野,真澄; 益子,良太大根田,修
日本癌学会総会記事 68: (2009)
52. THE ROLE OF CHEMOKINE SDF-1 AND CXCR4 IN GLIOMA ANGIOGENESIS AND INVASIVENESS: INTERACTION BETWEEN GLIOMA AND GLIOMA-DERIVED ENDOTHELIAL CELLS Shingo Takano; Satoru Osuka; Ryota Mashiko; Osamu Ohneda (+2 著者) Akira Matsumura
NEURO-ONCOLOGY 11: 219 (2009)
53. A Chemokine Receptor CXCR4 Plays a Crucial Role for Repairing Ischemic Tissue through Regulation of HIF-2a Masumi Nagano; Ken-ichi Kimura; Toshiharu Yamashita; Hiromi Hamada (+2 著者) Osamu Ohneda
BLOOD 112: 1336 (2008)
54. The microenvironment for erythropoiesis is regulated by HIF-2 alpha through VCAM-1 in endothelial cells Toshiharu Yamashita; Osamu Ohneda; Ai Sakiyama; Fumiko Iwata (+1 著者) Yoshiaki Fujii-Kuriyama
BLOOD 112: 1482 (2008) Semantic Scholar
55. Hypoxia-inducible transcription factor-2 alpha in endothelial cells regulates tumor neovascularization through activation of ephrin A1 Toshiharu Yamashita; Kinuko Ohneda; Masumi Nagano; Chika Miyoshi (+4 著者) Yoshiaki Fujii-Kuriyama
JOURNAL OF BIOLOGICAL CHEMISTRY 283: 18926 (2008) Semantic Scholar
56. Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS Toshiharu Yamashita; Osamu Ohneda; Masumi Nagano; Motoyuki Iemitsu (+7 著者) Masayuki Yamamoto
MOLECULAR AND CELLULAR BIOLOGY 28: 1285 (2008) Semantic Scholar
57. A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts organ protection against ischemia Masaomi Nangaku; Yuko Izuhara; Shunya Takizawa; Toshiharu Yamashita (+5 著者) Toshio Miyata
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 27: 2548 (2007) Semantic Scholar
58. Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood Masumi Nagano; Toshiharu Yamashita; Hiromi Hamada; Kinuko Ohneda (+4 著者) Osamu Ohneda
BLOOD 110: 151 (2007) Semantic Scholar
59. Protective role of hypoxia-inducible factor-2 alpha against ischemic damage and oxidative stress in the kidney Ichiro Kojima; Tetsuhiro Tanaka; Reiko Inagi; Hideki Kato (+7 著者) Masaomi Nangaku
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 18: 1218 (2007) Semantic Scholar
60. HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin. Morita,M; Ohneda,O; Yamashita,T; Takahashi,S (+10 著者) Fujii-Kuriyama,Y
EMBO J. 22: 1134-1146 (2003)

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1. HIFのin vivoモデルによる機能解析山下年晴; 大根田修 (担当:監修)
実験医学羊土社 2007年9月
2. 環境応答系転写因子の分子機構の解明山下年晴; 山本, 雅之 (担当:監修)
化学工業 2003年1月

1. Extracellular vesicles derived from Wharton’s Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway Yun-Hsuan, Chang; Vuong; Cat Khanh; Toshiharu, Yamashita; Osamu, Ohneda
Tsukuba Global Science Week 2022 2022年9月30日
2. Nicotine and SARS-CoV-2 Protein Induce the Malignancy of Lung Cancer Cell. International Student Presentations of Medical and Life Sciences Session. Lomanto; Markus Yovian Widjaja; Nguyen; Hoai-Nga Thi; Khanh, Vuong Ca; Yamashita, Toshiharu; Ohneda, Osamu
Tsukuba Global Science Week 2022 2022年9月29日
3. SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells Nguyen; Hoai-Nga Thi; Khanh, Vuong Ca; Yamashita, Toshiharu; Ohneda, Osamu
Tsukuba Global Science Week 2022 2022年9月29日
4. Transformed Extracellular Vesicles with High Angiogenic Ability as Therapeutics of Distal Ischemic Tissues Ngo, Nhat-Hoang; Khanh, Vuong Ca; Yamashita, Toshiharu; Ohneda, Osamu
Tsukuba Global Science Week 2022 2022年9月29日
5. Quantification of ex-vivo tissue activity by polarization dynamics imaging using Jones matrix optical coherence tomography Mukherjee, Pradipta; Miyazawa, Arata; Shen, Larina; Fukuda, Shinichi; Yamashita, Toshiharu; Oka, Yuki; Abd El-Sadek, Ibrahim; Makita, Shuichi; Matsusaka, Satoshi; Oshika, Tetsuro; Kano, Hideaki; Yasuno, Yoshiaki
Biomedical Imaging and Sensing Conference 2020 2020年8月24日
6. Effect of soy protein intake on weak bones by the food restriction in young female rats Y, Aikawa; T, Narukawa; K, Kioka; T, Yamashita; N, Sasai; M, Ohtsuki; 麻見, 直美
Human High Performance International Forum 2020 2020年2月17日 ARIHHPセンター
7. Quantification of ex vivo tissue activity by short and long timecourse analysis of multifunctional OCT signals El-Sadek; Ibrahim Abd; Miyazawa, Arata; Shen, Larina; Fukuda, Shinichi; Yamashita,Toshiharu; Oka, Yuki; Mukherjee, Pradipta; Makita, Shuichi; Matsusaka, Satoshi; Oshika, Tetsuro; Kano, Hideaki; Yasuno, Yoshiaki
SPIE Photonics West/ BiOS 2020 2020年2月1日
8. Impairment of Sirt1 plays the key role in the dysfunction of mesenchymal stem cells in beige adipogenesis Vuong Cat, Khanh; Yamashita, Toshiharu; Ohneda, Osamu
The Joint Young Research Meeting in Biomedical Science 2020年1月10日
9. Study the effects of type 2 diabetes mellitus on functions of Wharton jelly's Mesenchymal stem cells for the treatment of diabetic foot ulcer Sipayung; Shinta Masyta; Khanh, Vuong Ca; Yamashita, Toshiharu; Ohneda, Osamu
The Joint Young Research Meeting in Biomedical Science 2020年1月10日
10. Birefringence dynamics imaging for ex-vivo tissue activity quantification using polarization-sensitive optical coherence tomography Mukherjee, Pradipta; El-Sadek; Ibrahim Abd; Miyazawa, Arata; Makita, Shuichi; Shen, Larina; Fukuda, Shinichi; Yamashita, Toshiharu; Oka, Yuki; Matsusaka, Satoshi; Oshika, Tetsuro; Kano, Hideaki; Yasuno, Yoshiaki
Optics Photonics Japan 2019 （日本光学会年次講演会） 2019年12月2日
11. Short and long time-course ex vivo tissues activity quantification by multifunctional OCT El-Sadek; Ibrahim Abd; Miyazawa, Arata; Shen, Larina; Fukuda, Shinichi; Yamashita,Toshiharu; Oka, Yuki; Mukherjee, Pradipta; Makita, Shuichi; Matsusaka, Satoshi; Oshika, Tetsuro; Kano, Hideaki; Yasuno, Yoshiaki
Optics Photonics Japan 2019 （日本光学会年次講演会） 2019年12月2日
12. 老化による脂肪組織由来間葉系幹細胞の創傷治癒能に対する影響の解析原彩美; Vuong, Cat Khanh; Toshiharu, Yamashita; Osamu, Ohneda
第18回日本再生医療学会総会 2019年3月21日
13. より高い治療効果を持つ機能性血管内皮前駆細胞 (EPC) の作成佐藤悠樹; Vuong, Cat Khanh; Toshiharu, Yamashita; Osamu, Ohneda
第18回日本再生医療学会総会 2019年3月21日
14. Effects of aging on mesenchymal stem cells VUONG CAT; KHANH; Yamashita, Toshiharu; Ohneda, Osamu
The 1st University of Tsukuba-University of Science Vietnam Joint Symposium 2019 2019年2月23日
15. Study the effects of Type 2 diabetes mellitus on beige adipogenesis of Mesenchymal stem cells Takeuchi, Kosuke; Khanh, Vuong Ca; Yamashita, Toshiharu; Ohneda, Osamu
Tsukuba Science Week 2018 2018年9月20日
16. The ectopic FOXA1 expression correlates to the luminal breast cancer stem cells Tachi,K; Shiraishi,A; Bando,Hiroko; Yamashita,T; Tsuboi,I; Kato,T; Ichioka,E; Tsushima,Y; Ikeda,T; Iguchi,A; Hara,H; Ohneda,O
39Th San Antonio Breast Cancer Symposium 2016年12月6日
17. The ectopic FOXA1 expression correlates to the luminal breast cancer stem cells Tachi, K; Shiraishi, A; Bando, H; Yamashita, T; Tsuboi, I; Kato, T; Ichioka, E; Tsushima, Y; Ikeda, T; Iguchi, A; Hara, H; Ohneda, O
San Antonio Breast Cancer Symposium 2016年12月6日
18. 筑波大学における臨地実習前OSCEの開発に向けた取組會田, 雄一; 山内, 一由; 上妻, 行則; 渋谷, 和子; 上杉, 憲子; 中川, 嘉; 吉田, 文代; 山下, 年晴; 小池, 朗; 二宮, 治彦
第11回日本臨床検査学教育学会学術大会 2016年8月31日
19. Dual Functions of Hypoxia Inducible Factor-1 alpha for the Commitment of Mouse Embryonic Stem Cells Toward a Neural Lineage Takasaki,Mami; Zhao,Yang; Tsuboi,Ikki; Yamashita,Toshiharu; Ohneda,Osamu
第47回日本発生生物学会 2014年5月28日
20. Deficient expression of HIF-2a in spleen results in compensatory angiogenesis by up-regulated of HIF-1a IkkiTsuboi; 山下,年晴; Satomi,Kobayashi; Osamu,Ohneda
第36回日本分子生物学会 2013年12月3日