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柴 綾

ALUMNI 2026年8月現在、筑波大学が主たる所属機関ではありません

Shiba, Aya

筑波大学 , 医学医療系 , 准教授
University of Tsukuba , Institute of Medicine , Associate Professor

オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
  1. 1. ZEB1 expression in NEUROD1-positive and combined YAP1-dominant pulmonary neuroendocrine carcinomas is associated with a locally immunosuppressive microenvironment. Takemura-Kobayashi, Noriko; Asayama, Kei; Ibrahim; Rawya Mohamed (+5 著者) Matsubara, Daisuke
      CANCER RESEARCH 86: (2026)
  2. 2. Clinicopathological, Cellular and Molecular Analyses of Pulmonary Neuroendocrine Carcinoma with High Expression of Hepatocyte Nuclear Factor 4 Alpha Asayama, Kei; Matsuoka, Ryota; Tachi, Suzuka; Shiba-Ishii, Aya (+11 著者) Matsubara, Daisuke
      Laboratory investigation; a journal of technical methods and pathology 105: (2025) Semantic Scholar
  3. 3. Novel therapeutic strategies targeting bypass pathways and mitochondrial dysfunction to combat resistance to RET inhibitors in NSCLC Aya Shiba-Ishii; Takayuki Isagawa; Toshihiro Shiozawa; Naoko Mato (+8 著者) Daisuke Matsubara
      Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 167249 (2024) Semantic Scholar
  4. 4. Expression patterns of HNF4α, TTF‐1, and SMARCA4 in lung adenocarcinomas: impacts on clinicopathological and genetic features Hitomi Kawai; Tamaki Miura; Natsumi Kawamatsu; Tomoki Nakagawa (+14 著者) Toshiro Niki
      Virchows Archiv (2024)
  5. 5. Histologic transformation of non-small-cell lung cancer in response to tyrosine kinase inhibitors: Current knowledge of genetic changes and molecular mechanisms. Aya Shiba-Ishii, Noriko Takemura, Hitomi Kawai, Daisuke Matsubara
      Cancer Science (2024)
  6. 6. Spectrum of diverse compound resistance mutations and roadmap for targeting them in ALK-positive lung cancer Shiba, Aya; Johnson, Ted W.; Dagogo-Jack, Ibiayi; Mino-Kenudson, Mari (+3 著者) Hata, Aaron N.
      CANCER SCIENCE 115: 1104 (2024)
  7. 7. Investigation for on-target resistance mechanism to ALK inihbitors and development of novel therapiutic strategy to target early-stage lnug adenocarcinoma Shiba, Aya; Yoda, Satoshi; Hata, Aaron N.; Hirokawa, Takatsugu (+1 著者) Matsubara, Daisuke
      CANCER SCIENCE 115: 1261 (2024)
  8. 8. Mutational landscape of primary breast angiosarcoma with repeated resection and recurrence over a 15-year period: A case report Teruyama, Fumiya; Kuno, Akihiro; Murata, Yoshihiko; Nakagawa, Tomoki (+2 著者) Noguchi, Masayuki
      PATHOLOGY INTERNATIONAL 72: 457 (2022) Semantic Scholar
  9. 9. Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer Shiba-Ishii, Aya; Johnson, Ted; Dagogo-Jack, Ibiayi; Mino-Kenudson, Mari (+19 著者) Hata, Aaron N
      Nature cancer 3: 710 (2022) Semantic Scholar
  10. 10. Significance of stratifin in early progression of lung adenocarcinoma and its potential therapeutic relevance Shiba-Ishii, Aya
      PATHOLOGY INTERNATIONAL 71: 655 (2021) Semantic Scholar
  11. 11. Ovarian carcinoma immunoreactive antigen domain 2 controls mitochondrial apoptosis in lung adenocarcinoma Hong, Jeongmin; Shiba-Ishii, Aya; Kim, Yunjung; Noguchi, MasayukiSakamoto, Noriaki
      Cancer science Epub: (2021) Semantic Scholar
  12. 12. Gene expression profiles of the original tumors influence the generation of PDX models of lung squamous cell carcinoma Kim, Yunjung; Shiba-Ishii, Aya; Nakagawa, Tomoki; Takeuchi, Tomoyo (+3 著者) Sakamoto, Noriaki
      LABORATORY INVESTIGATION Epub: (2021) Semantic Scholar
  13. 13. Gene expression profiles of the original tumors influence the generation of PDX models of lung squamous cell carcinoma Kim, Yunjung; Shiba-Ishii, Aya; Nakagawa, Tomoki; Takeuchi, Tomoyo (+3 著者) Sakamoto, Noriaki
      LABORATORY INVESTIGATION Epub: (2021) Semantic Scholar
  14. 14. Gene expression profiles of the original tumors influence the generation of PDX models of lung squamous cell carcinoma Kim, Yunjung; Shiba-Ishii, Aya; Nakagawa, Tomoki; Takeuchi, Tomoyo (+3 著者) Sakamoto, Noriaki
      LABORATORY INVESTIGATION Epub: (2021) Semantic Scholar
  15. 15. Carcinogen-induced tumors in SFN-transgenic mice harbor a characteristic mutation spectrum of human lung adenocarcinoma Kim, Yunjung; Shiba-Ishii, Aya; Ramirez, Karina; Muratani, Masafumi (+2 著者) Noguchi, Masayuki
      Cancer science 110: 2431 (2019) Semantic Scholar
  16. 16. DNA hypomethylation-related overexpression of SFN, GORASP2 and ZYG11A is a novel prognostic biomarker for early stage lung adenocarcinoma Husni; Ryan Edber; Shiba-Ishii, Aya; Nakagawa, Tomoki (+6 著者) Noguchi, Masayuki
      Oncotarget 10: 1625 (2019) Semantic Scholar
  17. 17. Stratifin inhibits SCFFBW7 formation and blocks ubiquitination of oncoproteins during the course of lung adenocarcinogenesis Shiba-Ishii, Aya; Hong, Jeongmin; Hirokawa, Takatsugu; Kim, Yunjung (+5 著者) Noguchi, Masayuki
      Clinical cancer research : an official journal of the American Association for Cancer Research 25: 2809 (2019) Semantic Scholar
  18. 18. Heterotopic Expression of Ceruloplasmin in Lung Adenocarcinoma and its Possible Clinical Use as a Tumor Biomarker Matsuoka, R; Shiba, A; Sakashita, S; Minami, YNoguchi, M
      JOURNAL OF THORACIC ONCOLOGY 13: S561 (2018) Semantic Scholar
  19. 19. High expression of ovarian cancer immunoreactive antigen domain containing 2 (OCIAD2) is associated with poor prognosis in lung adenocarcinoma Sakashita, Mai; Sakashita, Shingo; Murata, Yoshihiko; Shiba-Ishii, Aya (+4 著者) Noguchi, Masayuki
      Pathology international 68: 596 (2018) Semantic Scholar
  20. 20. The Novel SFN Inhibitors Aprepitant and Ticagrelor Exert Anti-Tumor Effects Through Blocking of Oncoprotein Ubiquitination Shiba, A; Hong, J; Hirokawa, T; Kim, YNoguchil, M
      JOURNAL OF THORACIC ONCOLOGY 13: S519 (2018) Semantic Scholar
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  1. 1. Laboratory investigation; a journal of technical methods and pathology Asayama, Kei; Matsuoka, Ryota; Tachi, Suzuka; Shiba-Ishii, Aya; Murata, Yoshihiko; Nakagawa, Tomoki; Furuhashi, Yosuke; Kawai, Hitomi; Suzuki, Ayako; Suzuki, Yutaka; Kobayashi, Naohiro; Sato, Yukio; Hizawa, Nobuyuki; Murakami, Yoshinori; Niki, Toshiro; Matsubara, Daisuke
    ELSEVIER SCIENCE INC 2025年7月
  2. 2. 医学のあゆみ Vol.277 No.12 野口, 雅之; 柴 綾
    医歯薬出版 2021年6月
  3. 3. 病理と臨床 柴,綾; 里見 介史; 野口 雅之 (担当:分担執筆, 範囲:マイクロダイセクション法)
    2011年4月
  1. 1. Investigation for on-target resistance mechanism to ALK inhibitors and development of novel therapeutic strategy to target early-stage lung adenocarcinoma
    第82回日本癌学会学術総会 2023年9月 招待有り
  2. 2. Spectrum of diverse compound resistance mutations and roadmap for targeting them in ALK-positive lung cancer
    第82回日本癌学会学術総会 2023年9月 招待有り
  3. 3. 浸潤部にのみFGFR T790M遺伝子変異が認められた、L858R遺伝子変異肺腺癌の1例 坂下信悟; 柴 綾; 関本 隆太郎; 村田 佳彦; 南 優子; 野口 雅之; 佐藤, 幸夫
    第58回日本肺癌学会学術集会 2018年11月29日 日本肺癌学会
  4. 4. 浸潤部にのみ EGFR T790M 遺伝子変異が認められた，L858R 遺伝子変異肺腺癌の 1 例 坂下信悟; 柴綾; 関本隆太郎; 村田佳彦; 南優子; 佐藤幸夫; Noguchi, Masayuki
    第58回日本肺癌学会学術集会 2017年10月14日 日本肺癌学会
  5. 5. Stratifin Regulates Stabilization of Receptor Tyrosine Kinases via Activation of Ubiquitin-Specific Protease 8 in Lung Adenocarcinoma. Shiba, Aya; Kim, YunJung; Noguchi, Masayuki
    IASLC第18回世界肺癌学会議 2017年10月14日 International Association for the Study of Lung Cancer
  6. 6. SFN Stabilizes Oncoproteins through Binding with SKP1 to Block SCFFBW7 Ubiquiting Ligase. Hong, Jeongmin; Shiba, Aya; Kim, YunJung; Noguchi, Masayuki
    IASLC第18回世界肺癌学会議 2017年10月14日 International Association for the Study of Lung Cancer
  7. 7. Stratifin regulates stabilization of EGFR through activation of ubiquitin-specific protease 8 in lung adenocarcinoma． Kim, Yunjung; 綾, 柴; Noguchi, Masayuki
    第76回日本癌学会学術総会 2017年9月28日 日本癌学会
  8. 8. miR-3941 targets IGBP1 and is associated with malignant progression of lung adenocarcinoma 佐藤, 泰樹; 柴 綾; 坂下 信悟; 野口 雅之; 加野 准子
    日本病理学会総会 2017年4月28日
  9. 9. miR–3941: A Novel microRNA That Controls IGBP1 Expression and is Associated with Malignant Progression of Lung Adenocarcinoma． Noguchi,Masayuki; Taiki Sato; Aya,Shiba; Yun-Jung Kim; Tomoko,Dai; Shingo,Sakashita
    IASLC 17 TH WORLD CONFERENCE ON LUNG CANCER 2016年12月4日 IASLC
  10. 10. DNMT3a Expression Pattern and Its Prognostic Value in Lung Adenocarcinoma． Noguchi,Masayuki; Ryan,Edbert Husni; Aya,Shiba-Ishii; Shinji,Iyama; Toshihiro Shiozawa; Yunjung,Kim; Tomoki,Nakagawa; Taiki,Sato; Junko,Kano; Yuko,Minami
    第75回日本癌学会学術総会 2016年10月6日 日本癌学会
  11. 11. Stratifin-associated ubiquitin-specific protease 8 stabilizes cMet in lung adenocarcinoma Noguchi,Masayuki; Yunjung,Kim; Aya,Shiba-Ishii
    第75回日本癌学会学術総会 2016年10月6日 日本癌学会
  12. 12. DNMT3a Expression Pattern and Its Prognostic Value in Lung Adenocarcinoma Noguchi,Masayuki; Ryan,Edbert Husni; 柴綾; 猪山慎治; 塩澤利博; 南優子
    第56回日本肺癌学会学術集会 2015年11月26日 日本肺癌学会
  13. 13. Stratifin Accelerates Progression of Lung Adenocarcinoma at an Early Stage Noguchi,Masayuki; 柴綾; Yunjung,Kim
    IASLC2015（the 16th IASLC World Conference on Lung Cancer） 2015年9月9日
  14. 14. Inhibition of EGFR Lysosomal Degradation in Lung Adenocarcinoma by Ubiquitin-Specific Protease 8 and Stratifin Noguchi,Masayuki; Yun-Jung,Kim; Aya,Shiba
    IASLC2015（the 16th IASLC World Conference on Lung Cancer） 2015年9月7日
  15. 15. Stratifin overexpression in lung adenocarcinoma blocks SCF ubiquitin ligase and accelerates tumor growth 柴,綾; 井口 由香里; 森下 由紀雄; 塩澤 利博; 猪山 慎二; 加野 准子; 野口 雅之
    第36回日本分子生物学会年会 2013年12月3日
  16. 16. Stratifin expressed in early invasive lung adenocarcinoma functionally enhances tumor progression and down-regulates SCFFbw7 ubiquitin ligase activity Shiba,Aya; Iguchi,Yukari; Morishita,Yukio; Shiozawa,Toshihiro; Iyama,Shinji; Kano,Junko; Iemura,Shun-ichiro; Tohru,Natsume; Noguchi,Masayuki
    World Conference on Lung Cancer 2013年10月27日
  17. 17. HNF4 α発現を伴う肺神経内分泌癌 朝山, 慶; 松岡, 亮太; 柴, 綾; 河合, 瞳; 村田, 佳彦; 中川, 智貴; 鈴木, 絢子; 鈴木, 穣; 松原, 大祐
    第115回日本病理学会総会
  18. 18. 高悪性度神経内分泌肺癌における神経特異的クロマチン調節因子ACTL6Bの臨床的・分子生物学的意義の検討 牧 雅大; 松岡, 亮太; 朝山, 慶; 柴, 綾; 川松, 夏美; 関本, 隆太郎; 竹村, 紀子; 松原, 大祐
    第115回日本病理学会総会
  19. 19. ZEB1 expression in NEUROD1-positive and combined YAP1-dominant pulmonary neuroendocrine carcinomas is associated with a locally immunosuppressive microenvironment 竹村, 紀子; 朝山慶; Rawya; Mohamed Salih Ibrahim; 牧, 雅大; 松岡, 亮太; 柴, 綾; 鈴木, 絢子; 鈴木, 穣; 松原, 大祐
    AACR Annual Meeting 2026
  20. 20. 肺神経内分泌癌（NEC）と Secretogranin-3（SCG3） 関本隆太郎; 松原, 大祐; 松岡亮太; 河合瞳; 柴綾; 朝山慶; 竹村紀子; 臺知子; 中川智貴; 古橋陽輔
    第114回日本病理学会総会
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