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蕨栄治

Warabi, Eiji

医学医療系 , 准教授
Institute of Medicine , Associate Professor

オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。

1. 4-Hydroxy-2-nonenal causes nuclear accumulation of p62 by inhibiting Xpo1 and promoting the proteolytic pathway in the nucleus Kayama, Emi; Baoshuo, Ning; Tatsuno, Rinna; Nishi, Kanako (+5 著者) Warabi, Eiji
PloS one 20: (2025)
2. Intestinal epithelial cell-specific restoration of Nrf2 gene in whole-body-knockout mice ameliorates acute colitis Sato, Tatsuhiro; To, Keii; Sakurai, Fumika; Chihara, Kanako (+4 著者) Okada, Kosuke
Experimental animals (2025)
3. Muscle-derived IL-1β regulates EcSOD expression via the NBR1-p62-Nrf2 pathway in muscle during cancer cachexia Yamada, Mami; Warabi, Eiji; Oishi, Hisashi; Lira, Vitor A.Okutsu, Mitsuharu
JOURNAL OF PHYSIOLOGY-LONDON 602: 4215 (2024)
4. Dual-specificity phosphatases 13 and 27 as key switches in muscle stem cell transition from proliferation to differentiation Takuto, Hayashi; Shunya, Sadaki; Ryosuke, Tsuji; Risa, Okada (+11 著者) 藤田, 諒
Stem Cells 42: 830 (2024)
5. Macrophage specific restoration of the Nrf2 gene in whole-body knockout mice ameliorates steatohepatitis induced by lipopolysaccharide from Porphyromonas gingivalis through enhanced hepatic clearance Kanako, Chihara; Okada, Kosuke; Uchida, Fumihiko; Miura, Ikuru (+9 著者) Shoda, Junichi
PLOS ONE 18: e0291880 (2023) Semantic Scholar
6. Muscle p62 stimulates the expression of antioxidant proteins alleviating cancer cachexia Yamada, Mami; Warabi, Eiji; Oishi, Hisashi; Lira, Vitor AOkutsu, Mitsuharu
FASEB JOURNAL 37: (2023) Semantic Scholar
7. p62 Is a Potential Biomarker for Risk of Malignant Transformation of Oral Potentially Malignant Disorders (OPMDs) Takasaki, Ryo; Uchida, Fumihiko; Takaoka, Shohei; Ishii, Ryota (+5 著者) Yanagawa, Toru
CURRENT ISSUES IN MOLECULAR BIOLOGY 45: 7630 (2023) Semantic Scholar
8. Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination Sadaki, Shunya; Fujita, Ryo; Hayashi, Takuto; Nakamura, Ayano (+11 著者) Takahashi, Satoru
CELL REPORTS 42: (2023) Semantic Scholar
9. Stress Activated MAP Kinases and Cyclin-Dependent Kinase 5 Mediate Nuclear Translocation of Nrf2 via Hsp90α-Pin1-Dynein Motor Transport Machinery Ishii, Tetsuro; Warabi, Eiji; Mann, Giovanni E
Antioxidants (Basel, Switzerland) 12: (2023) Semantic Scholar
10. Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress Akiyama, Masahiro; Unoki, Takamitsu; Aoki, Hanako; Nishimura, Akiyuki (+7 著者) Kumagai, Yoshito
REDOX BIOLOGY 57: (2022) Semantic Scholar
11. Mechanisms underlying Nrf2 nuclear translocation by non-lethal levels of hydrogen peroxide: p38 MAPK-dependent neutral sphingomyelinase2 membrane trafficking and ceramide/PKC zeta/CK2 signaling Ishii, Tetsuro; Warabi, Eiji; Mann, Giovanni E
FREE RADICAL BIOLOGY AND MEDICINE 191: 191 (2022) Semantic Scholar
12. p62/Sqstm1 Rescue in Muscle Retards the Progression of Steatohepatitis in p62/Sqstm1-null Mice Fed a High-fat Diet Ishii, Akiko; Ikuru, Miura; Junichi, Shoda; Okada, Kosuke (+4 著者) Ariizumi, Shunichi
Frontiers in Physiology 13: (2022) Semantic Scholar
13. SQSTM1, a protective factor of SOD1-linked motor neuron disease, regulates the accumulation and distribution of ubiquitinated protein aggregates in neuron Mitsui, Shun; Otomo, Asako; Sato, Kai; Ishiyama, Masahito (+6 著者) Hadano, Shinji
NEUROCHEMISTRY INTERNATIONAL 158: 105364 (2022) Semantic Scholar
14. Antioxidative Self-Assembling Nanoparticles Attenuate the Development of Steatohepatitis and Inhibit Hepatocarcinogenesis in Mice. Okada, Kousuke; Warabi, Eiji; Suzuki, Hideo; Kanno, Naomi (+9 著者) Miura, Ikuru
ANTIOXIDANTS 11: 1939 (2022) Semantic Scholar
15. Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy Ono, Maiko; Komatsu, Masaaki; Ji, Bin; Takado, Yuhei (+10 著者) Higuchi, Makoto
Aging cell 21: e13615 (2022) Semantic Scholar
16. In vitro assessment of the inhibitory effect of goreisan extract and its ingredients on the P-glycoprotein drug transporter and cytochrome P-450 metabolic enzymes Takiyama, Mikina; Matsumoto, Takashi; Kaifuchi, Noriko; Mizuhara, Yasuharu (+2 著者) Mizoguchi, Kazushige
XENOBIOTICA 52: 511 (2022) Semantic Scholar
17. Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility Kulathunga, Kaushalya; Wakimoto, Arata; Hiraishi, Yukiko; Yadav (+7 著者) Hamada, Michito
SCIENTIFIC REPORTS 11: (2021) Semantic Scholar
18. Mechanisms underlying unidirectional laminar shear stress-mediated Nrf2 activation in endothelial cells: Amplification of low shear stress signaling by primary cilia Ishii, Tetsuro; Warabi, Eiji; Mann, Giovanni E
REDOX BIOLOGY 46: (2021) Semantic Scholar
19. Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes Nishida, Mikako; Yamashita, Nahoko; Ogawa, Taisaku; Koseki, Keita (+7 著者) Udono, Heiichiro
JOURNAL FOR IMMUNOTHERAPY OF CANCER 9: e002954 (2021) Semantic Scholar
20. Nuclear factor E2-related factor 2 (NRF2) deficiency accelerates fast fibre type transition in soleus muscle during space flight Hayashi, Takuto; Kudo, Takashi; Fujita, Ryo; Fujita, Shin-Ichiro (+10 著者) Takahashi, Satoru
Communications biology 4: 787 (2021) Semantic Scholar

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1. 医学のあゆみ蕨,栄治 (担当:分担執筆, 範囲:抗酸化ストレス応答と分子スポーツ医学)
2013年1月

21. BDNF differentially activates Nrf2 in astrocytes and neurons Ishii, Tetsuro; Warabi, Eiji; Mann, Giovanni E
19th Biennial Meeting of the Society-for-Free-Radical-Research-International (SFRRI) 2018年
22. 食餌によるメトトレキサート毒性の増強樋口, 貴士; 吉村, 美郁; 岡, 笑美; 川﨑, 綾; 蕨, 栄治; 水野, 聖哉; 小野, 栄夫; 高橋, 智; 當間, 重人; 土屋, 尚之; 古川, 宏
第28回日本リウマチ学会関東支部学術集会 2017年12月9日
23. 食餌によるメトトレキサート毒性の増強. 樋口, 貴士; 吉村, 美郁; 岡, 笑美; 川﨑, 綾; 蕨, 栄治; 水野, 聖哉; 小野, 栄夫; 高橋, 智; 當間, 重人; 土屋, 尚之; 古川, 宏
第３８回日本臨床薬理学会学術総会 2017年12月7日
24. Circadian control of p75 neurotrophin receptor leads to alternate activation of Nrf2 and c-Rel to reset energy metabolism in astrocytes via brain-derived neurotrophic factor Ishii, Tetsuro; Warabi, Eiji; Mann, Giovanni E
Joint Conference of the Physiological-Society and the American-Physiological-Society 2016年
25. Association Of Functional Polymorphisms In IRF2 With Systemic Lupus Erythematosus In a Japanese Population Kawasaki, Aya; Furukawa, Hiroshi; Nishida, Nao; Warabi, Eiji; Kondo, Yuya; Ito, Satoshi; Matsumoto, Isao; Kusaoi, Makio; Suda, Akiko; Nagaoka, Shouhei; Setoguchi, Keigo; Nagai, Tatsuo; Hirohata, Shunsei; Tokunaga, Katsushi; Takasaki, Yoshinari; Hashimoto, Hiroshi; Sumida, Takayuki; Tohma, Shigeto; Tsuchiya, Naoyuki
77th Annual Meeting of the American-College-of-Rheumatology / 48th Annual Meeting of the Association-of-Rheumatology-Health-Professionals 2013年10月26日
26. Establishment of Obese Model with Increase in Blood Pressure by Sequestosome 1 Knockout Gene Sakai, Satoshi; Warabi, Eiji; Inaba, Hiroko; Harada, Harumi; Yanagawa, Toru; Shimojo, Nobutake; Aonuma, Kazutaka; Ishii, Tetsuro
Basic Cardiovascular Sciences Conference 2009 2009年7月20日
27. Increased blood pressure at resting phase in A170-knockout mice, an Obese Model Sakai, Satoshi; Warabi, Eiji; Inaba, Hiroko; Harada, Harumi; Yanagawa, Toru; Suzuki, Eiko; Tomoo, Takashi; Ishii, Tetsuro
82nd Annual Meeting of the Japanese-Pharmacological-Society 2009年3月17日
28. 大Maf群転写因子はtype IIb筋線維を制御する主要な因子である定木, 駿弥; 藤田, 諒; 林, 卓杜; 中村, 綾乃; 岡村, 結; 布施谷, 清香; 濱田, 理人; 蕨, 栄治; 久野, 朗広; 村谷, 匡史; 石井, 亜紀子; 岡田, 理沙; 芝, 大; 工藤, 崇; 高橋, 智
第70回(2023年度)日本実験動物学会総会
29. Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination 定木, 駿弥; 藤田, 諒; 林, 卓杜; 中村, 綾乃; 岡村, 結; 布施谷, 清香; 濱田, 理人; 蕨, 栄治; 久野, 朗広; 村谷, 匡史; 石井, 亜紀子; 岡田, 理沙; 芝, 大; 武田, 伸一; 工藤, 崇; 高橋, 智
第31回(2023年度)日本運動生理学会大会
30. 速筋線維を制御する大Maf群転写因子の解析定木, 駿弥; 藤田, 諒; 林, 卓杜; 中村, 綾乃; 岡村, 結; 布施谷, 清香; 濱田, 理人; 蕨, 栄治; 久野, 朗広; 村谷, 匡史; 岡田, 理沙; 芝, 大; 工藤, 崇; 高橋, 智
第10回サルコペニア・フレイル学会大会
31. Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination 定木, 駿弥; 藤田, 諒; 林, 卓杜; 中村, 綾乃; 岡村, 結; 布施谷, 清香; 濱田, 理人; 蕨, 栄治; 久野, 朗広; 村谷, 匡史; 岡田, 理沙; 芝, 大; 伸一, 武田; 工藤, 崇; 高橋, 智
50TH EUROPEAN MUSCLE CONFERENCE
32. 月重力1/6 gは微小重力による筋萎縮を抑制するが、筋線維タイプの変化は抑制しない林, 卓杜; 藤田, 諒; 岡田, 理沙; 濱田, 理人; 布施谷, 清香; 金井, 真帆; 井上, 由理; 定木, 駿弥; 村谷, 匡史; 蕨, 栄治; 工藤, 崇; 芝, 大; 高橋, 智
第70回(2023年度)日本実験動物学会総会
33. 微小重力環境を利用した新規骨格筋制御遺伝子の探索林, 卓杜; 藤田, 諒; 岡田, 理沙; 濱田, 理人; 布施谷, 清香; 金井, 真帆; 井上, 由理; 定木, 駿弥; 村谷, 匡史; 蕨, 栄治; 工藤, 崇; 芝, 大; 高橋, 智
第9回(2023年度)日本筋学会学術集会
34. Analysis of the plastic changes induced in the soleus muscle under microgravity conditions 諒介, 辻; 林, 卓杜; 工藤, 崇; 藤田, 諒; 濱田, 理人; 岡田, 理沙; 村谷, 匡史; 芝, 大; 隆史, 鈴木; 蕨, 栄治; 雅之, 山本; 高橋, 智
74th International Astronautical Congress
35. 4-Hydroxy-2-nonenal （4-HNE）による p62の核内蓄積と核内タンパク質分解の促進蕨, 栄治
第96回日本生化学会大会
36. Nuclear export suppression of p62/Sqstm1 causes severe kidney failure in mice 蕨, 栄治
第96回日本生化学会大会
37. Physiological significance of nuclear-cytoplasmic shuttling of autophagy adaptor protein p62 蕨, 栄治
第95回日本生化学会大会
38. p62:Nrf2遺伝子二重欠損マウスの肝蔵、内臓脂肪、腸内環境の解析よりみた NASH発症機序の解明 Warabi, Eiji; 秋山健太郎; 正田純一
第41回日本肝臓学会東部会
39. 異物貪食能の増大により、菌体内毒素(LPS)のクリアランスを増大させ、LPS刺激による炎症応答を低下させる Warabi, Eiji; 小峰昇一; 秋山健太郎; 正田純一
第41回日本肝臓学会東部会
40. 継続的な運動負荷は菌体内毒素（LPS）クリアランスを増大させ、LPS刺激による炎症応答を低下させる Warabi, Eiji; 小峰昇一; 秋山健太郎; 正田純一
第71回日本体力医学会大会