ホーム > 水野 聖哉/ Mizuno, Seiya

水野 聖哉

Mizuno, Seiya

医学医療系 , 教授
Institute of Medicine , Professor

http://www.md.tsukuba.ac.jp/basic-med/lab-animal/

遺伝子改変マウス作製を高効率化する新技術　－初代個体での迅速な遺伝子機能解析を実現－

2026-07-30

水谷 英二 鈴木 颯 久野 朗広 康 宇鎭 杉山 文博 高橋 智 水野 聖哉
マウス卵母細胞の形成と再覚醒には「エキソシスト複合体」が重要

2025-01-22

水野 聖哉
Proofing gene editing helps avoid unintended mutations

2022-06-30

水野 聖哉
ゲノム編集の結果を正しく理解する〜複雑なゲノム編集変異を網羅的に解析する手法を開発〜

2022-01-19

水野 聖哉
ノックアウトマウス作製デザインが全自動でできるウェブツール”KOnezumi”の開発

2019-06-25

久野 朗広 水野 聖哉 高橋 智
オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
  1. 1. Highly efficient and low-mosaicism piggyBac transgenesis platform for rapid founder phenotyping Okamura, Eiichi; Matsumoto, Shoma; Mizutani, Eiji; Murata, Kazuya (+22 著者) Ema, Masatsugu
      iScience 29: (2026) Semantic Scholar
  2. 2. The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging. Daiki Kojima; Keisuke Yaku; Shotaro Kosugi; Ryunosuke Mitsuno (+15 著者) Jun Yoshino
      Aging cell 25: e70509 (2026) Semantic Scholar
  3. 3. UNC45B Reduction With Aging: A Myofiber-Intrinsic Promoting Factor for Sarcopenia Mishima, Taiga; Nagamune, Taiga; Tada, Saori; Watanabe, Daiki (+13 著者) Ogasawara, Riki
      Aging cell 25: (2026) Semantic Scholar
  4. 4. Mitochondrial vulnerability underlies myocarditis from COVID-19 mRNA vaccine Mori, Go; Yamamoto, Masayoshi; Ishikawa, Kaori; Tamashiro, Hiroaki (+3 著者) Kawaguchi, Atsushi
      Nature communications (2026) Semantic Scholar
  5. 5. Tm4sf19 inhibition alleviates imiquimod-induced psoriatic dermatitis by regulating inflammatory signaling pathways and keratinocyte proliferation in mice Kang, Min Gi; Park, Sujin; Hong, Eunji; Lee, Min-Jung (+16 著者) Kim, Seong-Jin
      INFLAMMATION RESEARCH 75: (2026) Semantic Scholar
  6. 6. Optimizing CRISPR precision in mouse embryos via microhomology-mediated end joining-dominant targeting. Khanui Lkhagvadorj; Eiichi Okamura; Taito Taki; Hayate Suzuki (+4 著者) Masatsugu Ema
      Communications biology 9: (2026) Semantic Scholar
  7. 7. miR-494 Deletion Improves Glucose Metabolism Independently of Obesity in Mice Sugawara, Lucia; Morino, Katsutaro; Iwasaki, Hirotaka; Ohashi, Natsuko (+11 著者) Kume, Shinji
      DIABETES 75: (2026) Semantic Scholar
  8. 8. Inhibition of MAFB and PI3K/AKT Signaling for Hereditary FSGS with Multicentric Carpotarsal Osteolysis USUI, Toshiaki; ISHIBASHI, Shun; Tanaka, Ryojiro; Morito, Naoki (+23 著者) Takahashi, Satoru
      J Am Soc Nephrol (2026)
  9. 9. STABILIZED MAFB ACTIVATES IGF-1/PI3K/AKT TO CAUSE FOCAL SEGMENTAL GLOMERULOSCLEROSIS IN MULTICENTRIC CARPOTARSAL OSTEOLOSIS: GENETIC AND PHARMACOLOGIC RESCUE ISHIBASHI, Shun; USUI, Toshiaki; MORITO, Naoki; HAMADA, Michito (+9 著者) TAKAHASHI, Satoru
      Kidney International Reports (2026)
  10. 10. Lysophosphatidic acid-mediated NF-κB activation promotes FOXC2 expression essential for lymphatic valve development Yasuda, Daisuke; Sato, Nana; Yanagida, Keisuke; Hashidate-Yoshida, Tomomi (+8 著者) Ishii, Satoshi
      The Journal of clinical investigation 136: (2026) Semantic Scholar
  11. 11. TSUMUGI: a platform for phenotype-driven gene network identification from comprehensive knockout mouse phenotyping data Akihiro Kuno; Kinari Matsumoto; Taito Taki; Satoru TakahashiSeiya Mizuno
      (2026) Semantic Scholar
  12. 12. HMGCR-related muscular dystrophy: a case of severe neonatal-onset form Upadia, Jariya; Li, Yuwen; Osaki, Yoshinori; Mizuno, Seiya (+1 著者) Shimano, Hitoshi
      NEUROMUSCULAR DISORDERS 58: (2026) Semantic Scholar
  13. 13. Spatiotemporal dynamics of CD73 in mouse retina under physiological conditions Ishii, Ryutaro; Sakurai, Keisuke; Hosomi, Nao; Fleischmann, Bernd K. (+2 著者) Yanagisawa, Hiromi
      Development (Cambridge, England) 153: (2026) Semantic Scholar
  14. 14. Essential Roles of Heparan Sulfate Endosulfatase Sulf1 in Reward and Aversion Learning Through Distinct Dopamine D1 and D2 Receptor Pathways in Male Mice Miya, Ken; Ohta, Ken; Keino-Masu, Kazuko; Okada, Takuya (+4 著者) Masu, Masayuki
      Journal of neurochemistry 170: (2026) Semantic Scholar
  15. 15. AltEx-BE: a tool for designing splice-site-targeting gRNAs for base editing-mediated exon skipping with exon-level annotations in diverse experimental animals Kinari MATSUMOTO; Akihiro KUNO; Seiya MIZUNO
      Experimental Animals (2026) Semantic Scholar
  16. 16. Rapid-Onset Therapeutic Effects of Delta Opioid Receptor Agonists on Depression-Like Behaviors Induced by Chronic Social Defeat Stress Tokuda, Akihisa; Nagumo, Yasuyuki; Kajino, Keita; Iio, Keita (+4 著者) Nagase, Hiroshi
      NEUROPSYCHOPHARMACOLOGY REPORTS 45: (2025) Semantic Scholar
  17. 17. KIF26A regulates the development and function of the main olfactory epithelium in mice Zhou, Ruyun; Nishimura, Wataru; Takahashi, Masanori; Mochizuki, Shinya (+3 著者) Noda, Yasuko
      SCIENTIFIC REPORTS 16: (2025) Semantic Scholar
  18. 18. Survivin knockout attenuates the progressiveness of BT549 triple negative-breast cancer cells: an in vitro study highlighting stemness and cellular stress response mechanisms Syahrani; Resda Akhra; Wanandi; Septelia Inawati (+6 著者) Puspita Eka
      MOLECULAR BIOLOGY REPORTS 52: (2025) Semantic Scholar
  19. 19. Haploinsufficiency of Runx2 restores the cranial sutures in a mouse model of Pdgfrb-related craniosynostosis. Eri Ogawa; Tomona Oikawa; Shinya Ayabe; Tomoru Miwa (+5 著者) Toshiki Takenouchi
      Human molecular genetics 34: 1856 (2025) Semantic Scholar
  20. 20. Efficient generation of single copy transgenic mice using piggyBat transposase from the little brown bat Myotis lucifugus†. Eiichi Okamura; Shoma Matsumoto; Hayate Suzuki; Yoko Tanimoto (+8 著者) Masatsugu Ema
      Biology of reproduction (2025) Semantic Scholar
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  1. 1. 炎症と免疫 水野,聖哉 (担当:分担執筆, 範囲:CRISPR-Cas9（ゲノム編集）)
    2015年
  2. 2. Clinical Neuroscience. 水野, 聖哉; Tra, Thi Huong Dinh; 杉山, 文博 (担当:分担執筆, 範囲:脳梁欠損症―マウスから解明される脳梁形成機構.)
    2015年

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