ホーム > 関谷 元博/ Sekiya, Motohiro
関谷 元博
Sekiya, Motohiro

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老化が進行する仕組みを解明し、血液からその程度を推定する方法を開発
2025-10-08
関谷 元博

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肥満がインスリン分泌細胞の機能を低下させる仕組みを解明
2023-08-09
島野 仁 関谷 元博

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Protein keeps liver metabolism in check
2022-05-31
関谷 元博 島野 仁

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メタボリックシンドロームを制御する代謝産物センサー分子を発見
2021-11-30
関谷 元博 島野 仁
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101.
Molecular association model of PPARα and its new specific and efficient ligand, pemafibrate: Structural basis for SPPARMα.
Yamamoto Y; Takei K; Arulmozhiraja S; Sladek V (+9 著者) Shimano H
Biochemical and Biophysical Research Communications 499: 239 (2018) Semantic Scholar
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102.
Molecular association model of PPARα and its new specific and efficient ligand, pemafibrate: Structural basis for SPPARMα
Yamamoto, Yuta; Takei, Kenta; Arulmozhiraja, Sundaram; Sladek, Vladimir (+9 著者) Shimano, Hitoshi
Biochemical and biophysical research communications (2018)
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103.
Computational design and molecular mechanism in oligomerization of C-terminal binding protein 2
Miyashita Yurina; Matsuo Naoya; Yamamoto Yuta; Nakano Shogo (+6 著者) Tokiwa Hiroaki
FASEB JOURNAL 32: (2018)
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104.
A Rare Coexistence of Pheochromocytoma and Parkinson's Disease With Diagnostic Challenges : A Case Report
Matsumura-Matsuda, Erika; Sekiya, Motohiro; Omoto, Miyoko; Santo, Kana (+9 著者) Shimano, Hitoshi
Internal Medicine (2018)
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105.
Elovl6の欠損はdb/dbマウスにおいてβ細胞量とインスリン分泌能を増大させることで血糖コントロールを改善する
松坂 賢; 趙 会; 本村 香織; 関谷 元博 (+2 著者) 島野 仁
糖尿病 61: S (2018)
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106.
脂肪酸伸長酵素Elovl6の嗅覚機能における役割
志村 拓哉; 松坂 賢; 大野 博; 本村 香織 (+4 著者) 島野 仁
日本臨床分子医学会学術総会プログラム・抄録集 55回: 74 (2018)
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107.
TFEL scan法を用いたapoAI遺伝子プロモーターのSNP解析
會田 雄一; 矢作 直也; 武内 謙憲; 朴 賢英 (+12 著者) 島野 仁
糖尿病 61: S (2018)
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108.
A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes
Xianying Piao; Naoya Yahagi; Yoshinori Takeuchi; Yuichi Aita (+17 著者) Hitoshi Shimano
FEBS Letters 592: 422 (2018) Semantic Scholar
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109.
A rare coexistence of pheochromocytoma and Parkinson’s disease with diagnostic challenges
Erika Matsumura-Matsuda; Motohiro Sekiya; Miyoko Omoto-Inuzuka; Kana Santo (+9 著者) Hitoshi Shimano
Internal Medicine 57: 979 (2018) Semantic Scholar
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110.
A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes
Piao, Xianying; Yahagi, Naoya; Takeuchi, Yoshinori; Aita, Yuichi (+17 著者) Shimano, Hitoshi
FEBS letters 592: 422 (2018) Semantic Scholar
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111.
Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry
Yoshikazu Sawada; Yoshihiko Izumida; Yoshinori Takeuchi; Yuichi Aita (+20 著者) Naoya Yahagi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 493: 40 (2017) Semantic Scholar
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112.
Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry
Sawada, Yoshikazu; Izumida, Yoshihiko; Takeuchi, Yoshinori; Aita, Yuichi (+20 著者) Yahagi, Naoya
Biochemical and biophysical research communications 493: 40 (2017) Semantic Scholar
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113.
Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity.
Zhao H; Matsuzaka T; Nakano Y; Motomura K (+14 著者) Shimano H
DIABETES 66: 1833 (2017) Semantic Scholar
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114.
Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice.
Takei K; Han SI; Murayama Y; Satoh A (+11 著者) Shimano H
Journal of diabetes investigation 8: 446 (2017) Semantic Scholar
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115.
Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity
Zhao, Hui; Matsuzaka, Takashi; Nakano, Yuta; Motomura, Kaori (+14 著者) Shimano, Hitoshi
Diabetes 66: 1833 (2017)
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116.
Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice
Kenta Takei; Song-iee Han; Yuki Murayama; Aoi Satoh (+11 著者) Hitoshi Shimano
JOURNAL OF DIABETES INVESTIGATION 8: 446 (2017) Semantic Scholar
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117.
Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice.
Takei K; Nakagawa Y; Wang Y; Han SI (+3 著者) Shimano H
JOURNAL OF PHARMACOLOGICAL SCIENCES 133: 214 (2017) Semantic Scholar
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118.
Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice
Takei, Kenta; Nakagawa, Yoshimi; Wang, Yunong; Han, Song-Iee (+3 著者) Shimano, Hitoshi
Journal of pharmacological sciences 133: 214 (2017) Semantic Scholar
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119.
A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.
Nishi-Tatsumi M; Yahagi N; Takeuchi Y; Toya N (+17 著者) Shimano H
FEBS letters 591: 965 (2017) Semantic Scholar
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120.
Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression
Kikuchi Takuya; Orihara Kana; Oikawa Fusaka; Han Song-iee (+15 著者) Shimano Hitoshi
Molecular Metabolism 5: 1092 (2016) Semantic Scholar
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