ホーム > 関谷 元博/ Sekiya, Motohiro
関谷 元博
Sekiya, Motohiro
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肥満がインスリン分泌細胞の機能を低下させる仕組みを解明
2023-08-09
島野 仁 関谷 元博
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Protein keeps liver metabolism in check
2022-05-31
関谷 元博 島野 仁
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メタボリックシンドロームを制御する代謝産物センサー分子を発見
2021-11-30
関谷 元博 島野 仁
オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
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101.
Plasma cholesterol-lowering and transient liver dysfunction in mice lacking squalene synthase in the liver
Nagashima,Shuichi; Yagyu,Hiroaki; Tozawa,Ryuichi; Tazoe,Fumiko (+8 著者) Ishibashi,Shun
JOURNAL OF LIPID RESEARCH 56: 998 (2015)
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102.
Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophages.
Sekiya M; Yamamuro D; Ohshiro T; Honda A (+9 著者) Ishibashi S
Journal of lipid research 55: 2082 (2014)
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103.
Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages
Kent Sakai; Masaki Igarashi; Daisuke Yamamuro; Taichi Ohshiro (+6 著者) Shun Ishibashi
JOURNAL OF LIPID RESEARCH 55: 2033 (2014)
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104.
Adipocyte lipid chaperone aP2 Is a secreted adipokine regulating hepatic glucose production
Haiming Cao; Motohiro Sekiya; Meric Erikci Ertunc; M. Furkan Burak (+7 著者) Gökhan S. Hotamisligil
Cell Metabolism 17: 768 (2013)
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105.
Apolipoprotein C-II deficiency with no rare variant in the APOC2 gene.
Takase S; Osuga J; Fujita H; Hara K (+21 著者) Okazaki H
Journal of atherosclerosis and thrombosis 20: 481 (2013)
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106.
Liver-specific deletion of 3-hydroxy-3-methylglutaryl coenzyme A reductase causes hepatic steatosis and death.
Nagashima S; Yagyu H; Ohashi K; Tazoe F (+6 著者) Ishibashi S
Arteriosclerosis, Trombosis, and Vascular Biology 32: 1824 (2012)
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107.
Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.
Saito R; Matsuzaka T; Karasawa T; Sekiya M (+13 著者) Shimano H
Arteriosclerosis, thrombosis, and vascular biology 31: 1973 (2011)
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108.
Sterol regulatory element-binding protein-1 determines plasma remnant lipoproteins and accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice.
Karasawa T; Takahashi A; Saito R; Sekiya M (+14 著者) Shimano H
Arteriosclerosis, thrombosis, and vascular biology 31: 1788 (2011)
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109.
Abrogation of neutral cholesterol ester hydrolytic activity causes adrenal enlargement.
Ohta K; Sekiya M; Uozaki H; Igarashi M (+15 著者) Osuga J
Biochemical and biophysical research communications 404: 254 (2011)
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110.
The Critical Role of Neutral Cholesterol Ester Hydrolase 1 in Cholesterol Removal From Human Macrophages
Masaki Igarashi; Jun-ichi Osuga; Hiroshi Uozaki; Motohiro Sekiya (+16 著者) Shun Ishibashi
CIRCULATION RESEARCH 107: 1387 (2010)
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111.
Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.
Takeuchi Y; Yahagi N; Izumida Y; Nishi M (+16 著者) Shimano H
The Journal of biological chemistry 285: 11681 (2010)
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112.
Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N-terminal sequence.
Masaki Igarashi; Jun-Ichi Osuga; Masashi Isshiki; Motohiro Sekiya (+9 著者) Shun Ishibashi
Journal of lipid research 51: 274 (2010)
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113.
Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.
Sekiya M; Osuga J; Nagashima S; Ohshiro T (+16 著者) Ishibashi S
Cell metabolism 10: 219 (2009)
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114.
Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.
Sekiya M; Yahagi N; Tamura Y; Okazaki H (+18 著者) Osuga J
Biochemical and biophysical research communications 387: 511 (2009)
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115.
Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages.
Okazaki H; Igarashi M; Nishi M; Sekiya M (+13 著者) Ishibashi S
The Journal of biological chemistry 283: 33357 (2008)
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116.
Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis
Motohiro Sekiya; Jun-ichi Osuga; Naoya Yahagi; Hiroaki Okazaki (+14 著者) Shun Ishibashi
JOURNAL OF LIPID RESEARCH 49: 1829 (2008)
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117.
In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression
Yoshinori Takeuchi; Naoya Yahagi; Yoshimi Nakagawa; Takashi Matsuzaka (+10 著者) Hitoshi Shimano
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 363: 329 (2007) Semantic Scholar
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118.
Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance
Takashi Matsuzaka; Hitoshi Shimano; Naoya Yahagi; Toyonori Kato (+21 著者) Nobuhiro Yamada
NATURE MEDICINE 13: 1193 (2007) Semantic Scholar
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119.
SREBP-1-independent regulation of lipogenic gene expression in adipocytes
Motohiro Sekiya; Naoya Yahagi; Takashi Matsuzaka; Yoshinori Takeuchi (+12 著者) Hitoshi Shimano
JOURNAL OF LIPID RESEARCH 48: 1581 (2007) Semantic Scholar
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120.
Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver
Hiroaki Okazaki; Fumiko Tazoe; Sachiko Okazaki; Naoyuki Isoo (+16 著者) Shun Ishibashi
JOURNAL OF LIPID RESEARCH 47: 1950 (2006) Semantic Scholar
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