ホーム > 吉野 龍ノ介/ Yoshino, Ryunosuke
吉野 龍ノ介
Yoshino, Ryunosuke
医学医療系 , 助教 Institute of Medicine , Assistant Professor
オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
-
1.
Prediction of the binding mechanism of a selective DNA methyltransferase 3A inhibitor by molecular simulation.
Genki Kudo; Takumi Hirao; Ryuhei Harada; Takatsugu Hirokawa (+1 著者) Ryunosuke Yoshino
Scientific reports 14: 13508 (2024) Semantic Scholar
-
2.
Site Identification and Next Choice Protocol for Hit-to-Lead Optimization
Kudo, Genki; Hirao, Takumi; Yoshino, Ryunosuke; Shigeta, Yasuteru (+1 著者) Takatsugu
JOURNAL OF CHEMICAL INFORMATION AND MODELING 64: 4475 (2024) Semantic Scholar
-
3.
AAp-MSMD: Amino Acid Preference Mapping on Protein-Protein Interaction Surfaces Using Mixed-Solvent Molecular Dynamics
Kudo, Genki; Yanagisawa, Keisuke; Yoshino, Ryunosuke; HirokawaTakatsugu
JOURNAL OF CHEMICAL INFORMATION AND MODELING 63: 7768 (2023) Semantic Scholar
-
4.
Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro, and X-ray Crystallography
Ryunosuke Yoshino; Nobuaki Yasuo; Yohsuke Hagiwara; Takashi Ishida (+9 著者) Masakazu Sekijima
ACS Omega (2023) Semantic Scholar
-
5.
Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity
Saito, Kenji; Sekiya, Motohiro; Kainoh, Kenta; Yoshino, Ryunosuke (+21 著者) Shimano, Hitoshi
J Biol Chem 299: 104890 (2023) Semantic Scholar
-
6.
Pocket to concavity: a tool for the refinement of protein-ligand binding site shape from alpha spheres
Kudo, Genki; Hirao, Takumi; Yoshino, Ryunosuke; Shigeta, Yasuteru (+1 著者) Takatsugu
BIOINFORMATICS 39: (2023) Semantic Scholar
-
7.
Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis.
Junya Tabata; Takashi Nakaoku; Mitsugu Araki; Ryunosuke Yoshino (+13 著者) Takashi Kohno
Cancer research 82: 3751 (2022) Semantic Scholar
-
8.
A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin.
Miho Watanabe-Takahashi; Miki Senda; Ryunosuke Yoshino; Masahiro Hibino (+4 著者) Kiyotaka Nishikawa
Scientific reports 12: 11443 (2022) Semantic Scholar
-
9.
Chemosynthetic ethanolamine plasmalogen stimulates gonadotropin secretion from bovine gonadotrophs by acting as a potential GPR61 agonist.
Hiroya Kadokawa; Ryunosuke Yoshino; Risa Saito; Takatsugu Hirokawa
Animal reproduction science 241: 106992 (2022) Semantic Scholar
-
10.
Inverse Mixed-Solvent Molecular Dynamics for Visualization of the Residue Interaction Profile of Molecular Probes.
Keisuke Yanagisawa; Ryunosuke Yoshino; Genki Kudo; Takatsugu Hirokawa
International journal of molecular sciences 23: (2022) Semantic Scholar
-
11.
Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
Kazue Inaba; Kana Ebihara; Miki Senda; Ryunosuke Yoshino (+20 著者) Ryusuke Niwa
BMC biology 20: 43 (2022) Semantic Scholar
-
12.
The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis.
Motohiro Sekiya; Kenta Kainoh; Takehito Sugasawa; Ryunosuke Yoshino (+8 著者) Hitoshi Shimano
Nature communications 12: 6315 (2021) Semantic Scholar
-
13.
Integrate in silico studies on the role of nicotinamide adenine dinucleotide (NADH) binding in activating C-terminal binding protein 2 (CtBP2)
Tsukasa, Aoyagi; Yoshino, Ryunosuke; Yuki, Mitsuta; Rikuri, Morita (+1 著者) Yasuteru, Shigeta
Chemistry Letters 51: 1 (2021) Semantic Scholar
-
14.
Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S-transferase Noppera-bo.
Kotaro Koiwai; Kana Morohashi; Kazue Inaba; Kana Ebihara (+9 著者) Ryusuke Niwa
Journal of pesticide science 46: 75 (2021) Semantic Scholar
-
15.
Identification of key interactions between SARS-CoV-2 main protease and inhibitor drug candidates.
Ryunosuke Yoshino; Nobuaki Yasuo; Masakazu Sekijima
Scientific reports 10: 12493 (2020) Semantic Scholar
-
16.
An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo.
Kotaro Koiwai; Kazue Inaba; Kana Morohashi; Sora Enya (+13 著者) Ryusuke Niwa
The Journal of biological chemistry 295: 7154 (2020) Semantic Scholar
-
17.
A prospective compound screening contest identified broader inhibitors for Sirtuin 1.
Shuntaro Chiba; Masahito Ohue; Anastasiia Gryniukova; Petro Borysko (+48 著者) Masakazu Sekijima
Scientific reports 9: 19585 (2019) Semantic Scholar
-
18.
Molecular Dynamics Simulation reveals the mechanism by which the Influenza Cap-dependent Endonuclease acquires resistance against Baloxavir marboxil.
Ryunosuke Yoshino; Nobuaki Yasuo; Masakazu Sekijima
Scientific reports 9: 17464 (2019) Semantic Scholar
-
19.
Parallel cascade selection molecular dynamics to screen for protein complexes generated by rigid docking.
Ryuhei Harada; Ryunosuke Yoshino; Hiroaki Nishizawa; Yasuteru Shigeta
Journal of molecular graphics & modelling 92: 94 (2019) Semantic Scholar
-
20.
Temperature-pressure shuffling outlier flooding method enhances the conformational sampling of proteins.
Ryuhei Harada; Ryunosuke Yoshino; Hiroaki Nishizawa; Yasuteru Shigeta
Journal of computational chemistry 40: 1530 (2019) Semantic Scholar
書籍等出版物情報はまだありません。
-
1.
DNAメチル基転移酵素阻害剤のアイソフォーム選択性の解明
工藤, 玄己; 重田, 育照; 原田, 隆平; 広川, 貴次; 吉野, 龍ノ介
日本コンピュータ化学会2021年 秋季年会 2021年11月2日
-
2.
Prediction of binding mechanism for DNA methyltransferase 3A selective inhibitor using molecular simulation approach
Kudo, Genki; Shigeta, Yasuteru; Harada, Ryuhei; Hirokawa, Takatsugu; Yoshino, Ryunosuke
CBI学会2021年大会 2021年10月26日
-
3.
分子シミュレーション技術を用いたタンパク質-リガンド間の分子認識メカニズムの解析
吉野,龍ノ介
第43回日本分子生物学会年会 2020年12月2日
-
4.
環状ペプチドにおける、溶媒の違いによる構造変化と自由エネルギー安定性の評価
柳, 昂輝; 重田, 育照; 西澤, 宏晃; 原田, 隆平; 吉野, 龍ノ介; 満田, 祐樹
日本コンピュータ化学会2019秋季年会 2019年10月24日 日本コンピュータ化学会
-
5.
環状ジペプチドの安定構造における系統的な傾向と特徴
栁, 昂輝; 西澤, 宏晃; 吉野, 龍ノ介; 原田, 隆平; 重田, 育照
第57回日本生物物理学会年会 2019年9月24日
-
6.
Discovery of a novel inhibitor of spermidine synthase for Chagas' disease by molecular dynamics and docking simulation
Yoshino,Ryunosuke
Asia Hub for e-Drug Discovery Symposium 2018年9月26日 招待有り
-
7.
Compound Property Enhancer by Virtual Compound Synthesis
Naoki Arai; Shunsuke Yoshikawa; Nobuaki Yasuo; Yoshino, Ryunosuke; Sekijima, Masakazu
The 28th International Conference on Genome Informatics GIW/BIOINFO 2017 2017年10月31日
-
8.
Hit-to-Lead最適化を目的とした立体構造に基づくリガンド伸長サイト予測
工藤玄己; 平尾巧; 吉野龍ノ介; 重田育照; 広川, 貴次
第23回日本蛋白質科学会年会
-
9.
Application of Parallel Cascade Selection Molecular Dynamics for Generating Virtual Screening Models
平尾巧; 工藤玄己; 吉野龍ノ介; 広川, 貴次
CBI学会2023年大会
-
10.
Comprehensive Structural Analysis of PROTAC Mediated Ternary Complexes using Enhanced Conformational Sampling Methods
工藤玄己; 平尾巧; 広川, 貴次; 吉野龍ノ介
CBI学会2023年大会
-
11.
Conformation Search of Ternary Complexes for Rational PROTAC Linker Design Using Enhanced Sampling Method
吉野龍ノ介; 工藤玄己; 平尾巧; 広川, 貴次
CBI学会2023年大会
-
12.
Hit-to-Leadを指向した官能基修飾始点と伸長サイトの予測手法開発
工藤玄己; 平尾巧; 吉野龍ノ介; 重田育照; 広川, 貴次
第 51 回構造活性相関シンポジウム
-
13.
拡張アンサンブル法を用いたPROTACリンカー設計のための三元複合体構造探索
吉野龍ノ介; 工藤玄己; 平尾巧; 広川, 貴次
第51回構造活性相関シンポジウム
-
14.
バーチャルスクリーニングモデル作成のためのParallel Cascade Selection Molecular Dynamicsの応用
平尾巧; 工藤玄己; 吉野龍ノ介; 広川, 貴次
第51回構造活性相関シンポジウム
-
15.
Amino acid preference mapping on protein-protein interaction surface using mixed-solvent molecular dynamics
Hirokawa, Takatsugu; G, Kudo; K, Yanagisawa; R, Yoshino
CBI学会2022年大会
-
16.
Molecular Dynamics for Visualization of Amino Acid Residue Interaction Profile of Molecular Probes
Hirokawa; Takatsugu; K, Yanagisawa; R, Yoshino; G, Kudo
日本生物物理学会第60回年会
知財情報はまだありません。
345 total views