ホーム > 吉野 龍ノ介/ Yoshino, Ryunosuke

吉野 龍ノ介

Yoshino, Ryunosuke

医学医療系 , 助教
Institute of Medicine , Assistant Professor

オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
  1. 1. Effects of chemosynthetic choline plasmalogens on gonadotropin secretion from bovine gonadotrophs Kadokawa, Hiroya; Niyonzima; Yvan Bienvenu; Hirokawa, TakatsuguYoshino, Ryunosuke
      The Journal of reproduction and development 71: 201 (2025)
  2. 2. CrypToth: Cryptic Pocket Detection through Mixed-Solvent Molecular Dynamics Simulations-Based Topological Data Analysis Koseki, Jun; Motono, Chie; Yanagisawa, Keisuke; Kudo, Genki (+2 著者) Imai, Kenichiro
      JOURNAL OF CHEMICAL INFORMATION AND MODELING (2025)
  3. 3. Prediction of the binding mechanism of a selective DNA methyltransferase 3A inhibitor by molecular simulation. Genki Kudo; Takumi Hirao; Ryuhei Harada; Takatsugu Hirokawa (+1 著者) Ryunosuke Yoshino
      Scientific reports 14: 13508 (2024) Semantic Scholar
  4. 4. Site Identification and Next Choice Protocol for Hit-to-Lead Optimization Kudo, Genki; Hirao, Takumi; Yoshino, Ryunosuke; Shigeta, Yasuteru (+1 著者) Takatsugu
      JOURNAL OF CHEMICAL INFORMATION AND MODELING 64: 4475 (2024) Semantic Scholar
  5. 5. AAp-MSMD: Amino Acid Preference Mapping on Protein-Protein Interaction Surfaces Using Mixed-Solvent Molecular Dynamics Kudo, Genki; Yanagisawa, Keisuke; Yoshino, Ryunosuke; HirokawaTakatsugu
      JOURNAL OF CHEMICAL INFORMATION AND MODELING 63: 7768 (2023) Semantic Scholar
  6. 6. Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro, and X-ray Crystallography Ryunosuke Yoshino; Nobuaki Yasuo; Yohsuke Hagiwara; Takashi Ishida (+9 著者) Masakazu Sekijima
      ACS Omega (2023) Semantic Scholar
  7. 7. Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity Saito, Kenji; Sekiya, Motohiro; Kainoh, Kenta; Yoshino, Ryunosuke (+21 著者) Shimano, Hitoshi
      J Biol Chem 299: 104890 (2023) Semantic Scholar
  8. 8. Pocket to concavity: a tool for the refinement of protein-ligand binding site shape from alpha spheres Kudo, Genki; Hirao, Takumi; Yoshino, Ryunosuke; Shigeta, Yasuteru (+1 著者) Takatsugu
      BIOINFORMATICS 39: (2023) Semantic Scholar
  9. 9. Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis. Junya Tabata; Takashi Nakaoku; Mitsugu Araki; Ryunosuke Yoshino (+13 著者) Takashi Kohno
      Cancer research 82: 3751 (2022) Semantic Scholar
  10. 10. A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin. Miho Watanabe-Takahashi; Miki Senda; Ryunosuke Yoshino; Masahiro Hibino (+4 著者) Kiyotaka Nishikawa
      Scientific reports 12: 11443 (2022) Semantic Scholar
  11. 11. Chemosynthetic ethanolamine plasmalogen stimulates gonadotropin secretion from bovine gonadotrophs by acting as a potential GPR61 agonist. Hiroya Kadokawa; Ryunosuke Yoshino; Risa Saito; Takatsugu Hirokawa
      Animal reproduction science 241: 106992 (2022) Semantic Scholar
  12. 12. Inverse Mixed-Solvent Molecular Dynamics for Visualization of the Residue Interaction Profile of Molecular Probes. Keisuke Yanagisawa; Ryunosuke Yoshino; Genki Kudo; Takatsugu Hirokawa
      International journal of molecular sciences 23: (2022) Semantic Scholar
  13. 13. Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti. Kazue Inaba; Kana Ebihara; Miki Senda; Ryunosuke Yoshino (+20 著者) Ryusuke Niwa
      BMC biology 20: 43 (2022) Semantic Scholar
  14. 14. The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis. Motohiro Sekiya; Kenta Kainoh; Takehito Sugasawa; Ryunosuke Yoshino (+8 著者) Hitoshi Shimano
      Nature communications 12: 6315 (2021) Semantic Scholar
  15. 15. Integrate in silico studies on the role of nicotinamide adenine dinucleotide (NADH) binding in activating C-terminal binding protein 2 (CtBP2) Tsukasa, Aoyagi; Yoshino, Ryunosuke; Yuki, Mitsuta; Rikuri, Morita (+1 著者) Yasuteru, Shigeta
      Chemistry Letters 51: 1 (2021) Semantic Scholar
  16. 16. Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S-transferase Noppera-bo. Kotaro Koiwai; Kana Morohashi; Kazue Inaba; Kana Ebihara (+9 著者) Ryusuke Niwa
      Journal of pesticide science 46: 75 (2021) Semantic Scholar
  17. 17. Identification of key interactions between SARS-CoV-2 main protease and inhibitor drug candidates. Ryunosuke Yoshino; Nobuaki Yasuo; Masakazu Sekijima
      Scientific reports 10: 12493 (2020) Semantic Scholar
  18. 18. An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. Kotaro Koiwai; Kazue Inaba; Kana Morohashi; Sora Enya (+13 著者) Ryusuke Niwa
      The Journal of biological chemistry 295: 7154 (2020) Semantic Scholar
  19. 19. A prospective compound screening contest identified broader inhibitors for Sirtuin 1. Shuntaro Chiba; Masahito Ohue; Anastasiia Gryniukova; Petro Borysko (+48 著者) Masakazu Sekijima
      Scientific reports 9: 19585 (2019) Semantic Scholar
  20. 20. Molecular Dynamics Simulation reveals the mechanism by which the Influenza Cap-dependent Endonuclease acquires resistance against Baloxavir marboxil. Ryunosuke Yoshino; Nobuaki Yasuo; Masakazu Sekijima
      Scientific reports 9: 17464 (2019) Semantic Scholar
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書籍等出版物情報はまだありません。

  1. 1. DNAメチル基転移酵素阻害剤のアイソフォーム選択性の解明 工藤, 玄己; 重田, 育照; 原田, 隆平; 広川, 貴次; 吉野, 龍ノ介
    日本コンピュータ化学会2021年 秋季年会 2021年11月2日
  2. 2. Prediction of binding mechanism for DNA methyltransferase 3A selective inhibitor using molecular simulation approach Kudo, Genki; Shigeta, Yasuteru; Harada, Ryuhei; Hirokawa, Takatsugu; Yoshino, Ryunosuke
    CBI学会2021年大会 2021年10月26日
  3. 3. 分子シミュレーション技術を用いたタンパク質－リガンド間の分子認識メカニズムの解析 吉野,龍ノ介
    第43回日本分子生物学会年会 2020年12月2日
  4. 4. 環状ペプチドにおける、溶媒の違いによる構造変化と自由エネルギー安定性の評価 柳, 昂輝; 重田, 育照; 西澤, 宏晃; 原田, 隆平; 吉野, 龍ノ介; 満田, 祐樹
    日本コンピュータ化学会2019秋季年会 2019年10月24日 日本コンピュータ化学会
  5. 5. 環状ジペプチドの安定構造における系統的な傾向と特徴 栁, 昂輝; 西澤, 宏晃; 吉野, 龍ノ介; 原田, 隆平; 重田, 育照
    第57回日本生物物理学会年会 2019年9月24日
  6. 6. Discovery of a novel inhibitor of spermidine synthase for Chagas' disease by molecular dynamics and docking simulation Yoshino,Ryunosuke
    Asia Hub for e-Drug Discovery Symposium 2018年9月26日 招待有り
  7. 7. Compound Property Enhancer by Virtual Compound Synthesis Naoki Arai; Shunsuke Yoshikawa; Nobuaki Yasuo; Yoshino, Ryunosuke; Sekijima, Masakazu
    The 28th International Conference on Genome Informatics GIW/BIOINFO 2017 2017年10月31日
  8. 8. タンパク質立体構造情報を利用した化合物生成AIによるHit-to-Lead 工藤, 玄己; 中島, 翔太; 市川, 裕大; 平尾, 巧; 吉野, 龍ノ介; 上島, 仁; 広川, 貴次
    第24回日本蛋白質科学会年会 日本蛋白質科学会
  9. 9. PROTAC-mediated ternary complex structure distribution profiles using enhanced sampling methods Kudo, Genki; Hirao, Takumi; Hirokawa, Takatsugu; Yoshino, Ryunosuke; HIROKAWA, Takatsugu
    IUPAB2024 IUPAB
  10. 10. Automated Hit-to-Lead Optimization using the SINCHO protocol and ChemTS 工藤玄己; 中島, 翔太; 市川, 裕大; 平尾, 巧; 吉野, 龍ノ介; 上島, 仁; 広川, 貴次
    CBI学会2024年大会 CBI学会
  11. 11. Structure-based Drug DesignにおけるAIを活用したリード化合物生成 工藤, 玄己; 中島, 翔太; 市川, 裕大; 平尾, 巧; 吉野, 龍ノ介; 上島, 仁; 広川, 貴次
    第41回メディシナルケミストリーシンポジウム 日本薬学会
  12. 12. Development of Structure- and AI-driven Lead Compound Generation System Kudo, Genki; Nakajima, Shota; Ichikawa, Yudai; Hirao, Takumi; Yoshino, Ryunosuke; Kamijima, Hitoshi; Shigeta, Yasuteru; HIROKAWA, Takatsugu
    ACS Spring 2025 米国化学会
  13. 13. Development of the Cryptic Site searching method with Mixed-solvent molecular dynamics and Topological data analyses methods Koseki, J.; Motono, C.; Yanagisawa, K.; Kudo, G.; Yoshino, R.; 広川, 貴次; Imai, K.
    1st Asia & Pacific Bioinformatics Joint Conference
  14. 14. Cryptic site detection using machine learning based on mixed-solvent molecular dynamics simulations results C, Motono; J, Koseki; K, Yanagisawa; G, Kudo; R, Yoshino; HIROKAWA, Takatsugu; K., Imai
    1st Asia & Pacific Bioinformatics Joint Conference
  15. 15. Development of a molecular simulation method for evaluating PROTAC linkers via ternary complex prediction 吉野, 龍ノ介; 工藤, 玄己; 平尾, 巧; 広川, 貴次
    日本薬学会第145年会 日本薬学会
  16. 16. Development of the Cryptic Site searching method with Mixed-solvent molecular dynamics and Topological data analyses methods Koseki, J.; Motono, C.; Yanagisawa, K.; Kudo, G.; Yoshino, R.; 広川, 貴次; Imai, K.
    CBI学会2024年大会 CBI学会
  17. 17. AIと立体構造情報を活用したリード化合物提案システムの開発と適用 工藤玄己; 中島, 翔太; 市川, 裕大; 平尾, 巧; 吉野, 龍ノ介; 上島, 仁; 広川, 貴次
    日本薬学会第145年会 日本薬学会
  18. 18. Hit-to-Lead最適化を目的とした立体構造に基づくリガンド伸長サイト予測 工藤玄己; 平尾巧; 吉野龍ノ介; 重田育照; 広川, 貴次
    第23回日本蛋白質科学会年会
  19. 19. Application of Parallel Cascade Selection Molecular Dynamics for Generating Virtual Screening Models 平尾巧; 工藤玄己; 吉野龍ノ介; 広川, 貴次
    CBI学会2023年大会
  20. 20. Comprehensive Structural Analysis of PROTAC Mediated Ternary Complexes using Enhanced Conformational Sampling Methods 工藤玄己; 平尾巧; 広川, 貴次; 吉野龍ノ介
    CBI学会2023年大会
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