ホーム > 高橋 智/ Takahashi, Satoru
高橋 智
Takahashi, Satoru
医学医療系 , 系長 Institute of Medicine , Provost
http://www.md.tsukuba.ac.jp/public/basic-med/anatomy/embryology/index.html
-
筋肉の形成を始める幹細胞のスイッチ分子を解明
2024-07-12
藤田 諒 高橋 智
-
食道扁平上皮がんにおいて生体防御遺伝子が高頻度に変異する原因を解明
2024-04-19
高橋 智
-
肝臓の中で胆管ができる仕組みを解明
2023-12-25
高橋 智
-
筋肉は重力低下で変化する人類の宇宙進出の課題解決へ
2023-06-12
高橋 智 工藤 崇 藤田 諒
-
筋肉を速筋タイプにする転写因子を同定〜加齢や病気で低下した筋機能の改善方法開発に期待〜
2023-03-24
高橋 智 藤田 諒
-
転写因子c-Mafの発現時期の制御により糖尿病や慢性腎臓病が治療できる可能性を発見
2023-02-28
高橋 智
-
なぜ胆管は門脈の隣にだけあるのか?~特異な細胞と組織内の均一性のせめぎあい~
2021-09-14
高橋 智
-
酸化ストレスに対抗するタンパク質が微小重力下での筋線維タイプの変化を抑制する
2021-09-07
高橋 智
-
日本実験動物学会 安東・田嶋賞
2020-06-29
高橋 智
-
肝臓のインスリン感受性を制御する脂質を発見
2019-12-31
島野 仁 松坂 賢 高橋 智
-
Resource competition drives stem cell fate
2019-08-28
杉山 文博 高橋 智 小林 悟
-
ノックアウトマウス作製デザインが全自動でできるウェブツール”KOnezumi”の開発
2019-06-25
久野 朗広 水野 聖哉 高橋 智
-
からだの死細胞を取り除く仕組みの解明
2018-02-06
濱田 理人 高橋 智
-
脳梗塞の炎症が収束するメカニズムを解明 ~白血病治療薬による脳梗塞の悪化阻止を確認~
2017-07-25
高橋 智
-
動脈硬化の進行を促進するたんぱく質を発見
2016-02-16
濱田 理人 高橋 智
オープンアクセス版の論文は「つくばリポジトリ」で読むことができます。
-
1.
4-Hydroxy-2-nonenal causes nuclear accumulation of p62 by inhibiting Xpo1 and promoting the proteolytic pathway in the nucleus
Kayama, Emi; Baoshuo, Ning; Tatsuno, Rinna; Nishi, Kanako (+5 著者) Warabi, Eiji
PloS one 20: (2025)
-
2.
Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation
Park, Sujin; Yoon, Kwiyeom; Hong, Eunji; Kim, Min Woo (+18 著者) Kim, Seong-Jin
BONE RESEARCH 13: (2025)
-
3.
Exocyst complex component 1 (Exoc1) loss in dormant oocyte disrupts c-KIT and growth differentiation factor (GDF9) subcellular localization and causes female infertility in mice
Nguyen, Chi Lieu Kim; Kuba, Yumeno; Le, Hoai Thu; Shawki (+20 著者) Mizuno, Seiya
Cell death discovery 11: 17 (2025)
-
4.
Legius syndrome mutations in the Ras-regulator SPRED1 abolish its membrane localization and potentially cause neurodegeneration
Hirata, Yasuko; Brems, Hilde; van der Auweraer; Seppe (+8 著者) Yoshimura, Akihiko
JOURNAL OF BIOLOGICAL CHEMISTRY 300: (2024)
-
5.
Partial activation of SIK3 delays the onset of wakefulness and alleviates hypersomnia due to the lack of protein kinase A-phosphorylation site
Nakata, Shinya; Fujiyama, Tomoyuki; Asano, Fuyuki; Komiya, Haruna (+9 著者) Yanagisawa, Masashi
Sleep (2024)
-
6.
Artificial Gravity Attenuates the Transcriptomic Response to Spaceflight in the Optic Nerve and Retina
Kremsky, Isaac; Pergerson, Reyna; Justinen, Stephen; Stanbouly, Seta (+6 著者) Mao, Xiaowen
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 25: (2024)
-
7.
Impact of microgravity and lunar gravity on murine skeletal and immune systems during space travel
Okamura, Yui; Gochi, Kei; Ishikawa, Tatsuya; Hayashi, Takuto (+21 著者) Takahashi, Satoru
Scientific reports 14: (2024) Semantic Scholar
-
8.
Simulation of murine retinal hemodynamics in response to tail suspension
Caddy, Harrison T.; Fujino, Mitsunori; Vahabli, Ebrahim; Voigt, Valentina (+5 著者) Doyle, Barry J.
Computers in biology and medicine 182: (2024) Semantic Scholar
-
9.
Novel integrated multiomics analysis reveals a key role for integrin beta-like 1 in wound scarring
Kim, Sang-Eun; Noda, Ryota; Liu, Yu-Chen; Nakajima, Yukari (+14 著者) Mori, Ryoichi
EMBO REPORTS Epub: (2024)
-
10.
Systemic Skeletal Bone Loss and Local Periarticular Bone Resorption in a Mouse Model of Multicentric Carpo-Tarsal Osteolysis (MCTO)
Jing, Xingzhi; Raval, Dhairya; Hu, Dorothy; Berry, Shawn (+4 著者) Baron, Roland
JOURNAL OF BONE AND MINERAL RESEARCH 39: 267 (2024)
-
11.
Dual-specificity phosphatases 13 and 27 as key switches in muscle stem cell transition from proliferation to differentiation
Takuto, Hayashi; Shunya, Sadaki; Ryosuke, Tsuji; Risa, Okada (+11 著者) 藤田, 諒
Stem Cells 42: 830 (2024)
-
12.
MAFB in Macrophages Regulates Prostaglandin E2–Mediated Lipid Mediator Class Switch through ALOX15 in Ischemic Acute Kidney Injury
Kanai, Maho; Nishino, Teppei; Daassi, Dhouha; Kimura, Akari (+8 著者) Hamada, Michito
The Journal of Immunology 213: (2024)
-
13.
B Cells of Early-life Origin Defined fi ned by RAG2-based Lymphoid Cell Tracking under Native Hematopoietic Conditions
Fujisaki, Keiko; Okazaki, Shogo; Ogawa, Shuhei; Takeda, Miyama (+4 著者) Goitsuka, Ryo
JOURNAL OF IMMUNOLOGY 213: (2024)
-
14.
Impaired Glycosylation of Gastric Mucins Drives Gastric Tumorigenesis and Serves as a Novel Therapeutic Target
Arai, Junya; Hayakawa, Yoku; Tateno, Hiroaki; Murakami, Keita (+31 著者) Fujishiro, Mitsuhiro
Gastroenterology 167: 505-521.e19 (2024) Semantic Scholar
-
15.
PCPE-1, a brown adipose tissue-derived cytokine, promotes obesity-induced liver fibrosis
Hsiao, Yung Ting; Yoshida, Yohko; Okuda, Shujiro; Abe, Manabu (+13 著者) Shimizu, Ippei
EMBO JOURNAL Epub: (2024) Semantic Scholar
-
16.
Reconstruction of Sjögren's syndrome-like sialadenitis by a defined disease specific gut-reactive single TCR and an autoantibody
Iizuka-Koga, Mana; Ito, Minako; Yumoto, Noriko; Mise-Omata, Setsuko (+6 著者) Yoshimura, Akihiko
Clinical immunology (Orlando, Fla.) 264: (2024) Semantic Scholar
-
17.
MAST4 regulates stem cell maintenance with DLX3 for epithelial development and amelogenesis
Lee, Dong-Joon; Kim, Pyunggang; Kim, Hyun-Yi; Park, Jinah (+8 著者) Kim, Seong-Jin
EXPERIMENTAL AND MOLECULAR MEDICINE 56: 1606 (2024) Semantic Scholar
-
18.
Vaccine Therapy for Heart Failure Targeting the Inflammatory Cytokine Igfbp7
Katoh, Manami; Nomura, Seitaro; Yamada, Shintaro; Ito, Masamichi (+29 著者) Komuro, Issei
CIRCULATION 150: 374 (2024) Semantic Scholar
-
19.
Deletion of Exoc7, but not Exoc3, in male germ cells causes severe spermatogenesis failure with spermatocyte aggregation in mice
Mikami, Natsuki; Nguyen, Chi Lieu Kim; Osawa, Yuki; Kato, Kanako (+8 著者) Mizuno, Seiya
Experimental animals 73: 286 (2024) Semantic Scholar
-
20.
Release of CD36-associated cell-free mitochondrial DNA and RNA as a hallmark of space environment response
Husna, Nailil; Aiba, Tatsuya; Fujita, Shin-Ichiro; Saito, Yoshika (+4 著者) Muratani, Masafumi
Nature communications 15: 4814 (2024) Semantic Scholar
-
1.
実験医学増刊 Vol.43 No.5 骨格筋の老化によるサルコペニア その理解と戦略〜筋生物学を超えた総合知で、運動・栄養・創薬による介入をめざす
藤田, 諒; 高橋智
羊土社 2025年3月 (ISBN: 4758104255)
-
2.
生化学
高橋, 智
2022年12月
-
3.
LABIO21
工藤, 崇; 岡田, 理沙; 篠原, 正治; 浅原, 弘嗣; 芝, 大; 白川, 正輝; 高橋, 智
(担当:分担執筆, 範囲:マウスを用いた宇宙環境応答の網羅的解析)
日本実験動物協会 2018年4月
-
4.
実験医学別冊 マウス表現型解析スタンダード
工藤, 崇; 高橋, 智
(担当:分担執筆, 範囲:マウスを用いた日本発の宇宙実験)
羊土社 2016年11月 (ISBN: 9784758101981)
-
5.
セラピューティック・リサーチ
濱田, 理人; 高橋智; 中村恵弥
(担当:分担執筆, 範囲:動脈硬化病変形成におけるMafBの機能)
2014年9月
-
6.
BIOLOGY OF KRUPPEL-LIKE FACTORS
Ema, Masatsugu; Takahashi, Satoru; Fujii-Kuriyama, Yoshiaki
(担当:分担執筆, 範囲:Kruppel-like Factors in Stem Cell Biology)
SPRINGER-VERLAG TOKYO 2009年1月
-
7.
ヒトの生物学
永田恭介他; 高橋, 智
(担当:単訳)
丸善株式会社 2007年12月
-
141.
サルコペニア克服に向けた骨格筋線維タイプ制御機構の解明
藤田, 諒; 定木, 駿弥; 林, 卓杜; 辻, 諒介; 工藤, 崇; 高橋, 智
第10回 日本サルコペニア・フレイル学会大会 一般社団法人日本サルコペニア・フレイル学会 招待有り
-
142.
Hevin/Sparcl1の変異によるASD病態形成への新たな洞察
武富巧; 保田拓範; 森田陸離; 原田隆平; 重田育照; 水野聖哉; 高橋智; 鶴田文憲
第46回日本神経科学大会
-
143.
Cytokine balance modulation in psychiatric disorders
Tetsuya, Saasaki; Sara, Kamiya; Satoru, Takahashi; Yosuke, Takei
The 11th Developmental Origins of Health and Disease Research The Japan Society of Developmental Origins of Health and Disease
-
144.
Effectiveness of Imatinib Formcto Nephropathy
Usui, Toshiaki; Morito, Naoki; Ishibashi, Shun; Gogoleva, Natalia; Kanai, Maho; Inoue, Yuri; Fuseya, Sayaka; Kuno, Akihiro; Mizuno, Seiya; Hamada, Michito; Takahashi, Satoru; Yamagata, Kunihiro
60th ERA Congress
-
145.
ポドサイト特異的MafB活性化物質のハイスループットスクリーニングの確立
臼井, 俊明; 森戸, 直記; 石橋, 駿; 金井, 真帆; 竹村, めぐみ; 全, 孝静; 濱田, 理人; 高橋, 智; 山縣, 邦弘
第66回日本腎臓学会学術総会
-
146.
Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination
Fujita, Ryo; Sadaki, Shunya; Takahashi, Satoru
1st Symposium on "Skeletal muscle cells in Growth and Disease" Philippos Mourikis 招待有り
-
147.
Tyrosinase mutations, a novel predisposing genetic factor for enhanced non-alcoholic steatohepatitis susceptibility
Kulathunga, Kaushalya; Wakimoto, Arata; Hamada, Michito; Takahashi, Satoru
International Liver Congress
-
148.
ASD-associated SPARCL1 mutant accumulates in the endoplasmic reticulum: implication for a novel mechanism underlying ASD pathogenesis
Taketomi, Takumi; Yasuda, Takunori; Morita, Rikuri; Shigeta, Yasuteru; Mizuno, Seiya; Takahashi, Satoru; Harada, Ryuhei; Tsuruta, Fuminori
36th International mammalian Genome society
-
149.
Molecular characterization of space environment responses in internal tissues by cell-free DNA and RNA analysis of plasma samples collected from six astronauts.
Rutter, Lindsay; Husna, Nailil; Fujita, Shin-ichiro; Saito, Yoshika; Kudo, Takashi; Takahashi, Satoru; Muratani, Masafumi
American Society for Gravity and Space Research (ASGSR) Annual Conference 2022
-
150.
腎内におけるNotch1シグナルの可視化
吉原, 雅大; 杉浦涼介; 高橋智
日本解剖学会第110回関東支部学術集会
-
151.
Notch1シグナル可視化マウス系の樹立
三瓶直人; 吉原, 雅大; 高橋智
日本解剖学会第110回関東支部学術集会
-
152.
Effects of T cell-specific retinoic acid orphan receptor factor-related nuclear receptor overexpression on poly(I:C)-induced abortion rate and central nervous system
Yosuke, Takei; Haruka, Kanamaru; Suguru, Iwata; Yoshitoku, Watabe; Yohei, Soga; Satoru, Takahashi; Tetsuya, Sasaki
The 128th Annual Meeting of The Japanese Association of Anatomists Japanese Association of Anatomists
-
153.
Loss of the Gata1 Gene IE Exon Leads to Variant Transcript Expression and the Production of GATA1 Protein Lacking the N-Terminal Domain
Kobayashi, Eri; Shimizu, Ritsuko; Kikuchi, Yuko; Takahashi, Satoru; Yamamoto, Masayuki
51st Annual Meeting of the American-Society-of-Hematology
-
154.
Kruppel-like Factors in Stem Cell Biology
Ema, Masatsugu; Takahashi, Satoru; Fujii-Kuriyama, Yoshiaki
1st International Symposium on Biology of Kruppel-Like Foctors
-
1. : Keap1遺伝子改変による異物代謝系第2相強化非ヒト動物の作出方法
高橋, 智 -
2. PCT/JP2018/042635: 非ヒト動物及びその製造方法
濱田, 理人; 高橋智; 全孝静 -
3. 得願2017-222215: 非ヒト動物及びその製造方法
濱田, 理人; 高橋智; 全孝静
5,430 total views